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Genetics and Molecular Biology
UK
2024

D-Index & Metrics

Molecular Biology

D-Index
105
Citations
40526
World Ranking
446
National Ranking
32

Research.com Recognitions

  • 2024 - Research.com Genetics and Molecular Biology in United Kingdom Leader Award
  • 1987 - Fellow of the Royal Society, United Kingdom
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Member of the European Molecular Biology Organization (EMBO)
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Terence H. Rabbitts is affiliated with the John Radcliffe Hospital in the United Kingdom. Their research primarily spans the fields of Medicine as well as Biochemistry, Genetics, and Molecular Biology. Subfields of focus include Molecular Biology, Infectious Diseases, Oncology, Radiology, Nuclear Medicine and Imaging, and Immunology.

Their research topics cover a variety of areas related to molecular and cellular mechanisms, including:

  • Monoclonal and Polyclonal Antibodies Research
  • SARS-CoV-2 and COVID-19 Research
  • Protein Degradation and Inhibitors
  • Ubiquitin and Proteasome Pathways
  • Angiogenesis and VEGF in Cancer
  • CAR-T Cell Therapy Research
  • Virus-based Gene Therapy Research

Recent published papers include:

  • Defining variant-resistant epitopes targeted by SARS-CoV-2 antibodies: A global consortium study, 2021, Science
  • A potent KRAS macromolecule degrader specifically targeting tumours with mutant KRAS, 2020, Nature Communications
  • A super-potent tetramerized ACE2 protein displays enhanced neutralization of SARS-CoV-2 virus infection, 2021, Scientific Reports
  • Multimeric antibodies with increased valency surpassing functional affinity and potency thresholds using novel formats, 2020, mAbs
  • Salmonella-based platform for efficient delivery of functional binding proteins to the cytosol, 2020, Communications Biology

Frequent co-authors collaborating with this scientist include:

  • Ami Miller
  • Nicolas Béry
  • Carole J. R. Bataille
  • Adam Leach

The most common publication venues where their work has appeared are:

  • Scientific Reports
  • Research Square
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Science Advances
  • BIO-PROTOCOL

Terence H. Rabbitts has been recognized by several professional bodies, including being named a Fellow of the Royal Society, United Kingdom, in 1987. They are also a Fellow of The Academy of Medical Sciences, United Kingdom, and a Member of the European Molecular Biology Organization (EMBO).

Best Publications

  • LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1.

    S. Hacein-Bey-Abina;C. Von Kalle;C. Von Kalle;M. Schmidt;M. P. McCormack

  • Chromosomal translocations in human cancer.

    Rabbitts Th

  • Production of chimeric antibodies

    Michael Samuel Neuberger;Terence Howard Rabbitts

  • The LIM‐only protein Lmo2 is a bridging molecule assembling an erythroid, DNA‐binding complex which includes the TAL1, E47, GATA‐1 and Ldb1/NLI proteins

    Isobel A. Wadman;Hirotaka Osada;Gerald G. Grütz;Alan D. Agulnick

  • THE ONCOGENIC CYSTEINE-RICH LIM DOMAIN PROTEIN RBTN2 IS ESSENTIAL FOR ERYTHROID DEVELOPMENT

    Alan J. Warren;William H. Colledge;Mark B.L. Carlton;Martin J. Evans

  • Fusion of the dominant negative transcription regulator CHOP with a novel gene FUS by translocation t(12;16) in malignant liposarcoma.

    T H Rabbitts;A Forster;R Larson;P Nathan

  • An Mll–AF9 Fusion Gene Made by Homologous Recombination Causes Acute Leukemia in Chimeric Mice: A Method to Create Fusion Oncogenes

    Javier Corral;Isabelle Lavenir;Helen Impey;Alan J Warren

  • Arrangement of human immunoglobulin heavy chain constant region genes implies evolutionary duplication of a segment containing gamma, epsilon and alpha genes.

    J G Flanagan;T H Rabbitts

  • Two tandemly organized human genes encoding the T-cell gamma constant-region sequences show multiple rearrangement in different T-cell types.

    Marie-Paule Lefranc;T. H. Rabbitts

  • A hapten-specific chimaeric IgE antibody with human physiological effector function.

    M. S. Neuberger;G. T. Williams;E. B. Mitchell;S. S. Jouhal

  • The rhombotin family of cysteine-rich LIM-domain oncogenes: distinct members are involved in T-cell translocations to human chromosomes 11p15 and 11p13.

    T Boehm;L Foroni;Y Kaneko;M F Perutz

  • The LIM domain: a new structural motif found in zinc-finger-like proteins.

    I Sánchez-García;T H Rabbitts

  • Diversity and rearrangement of the human T cell rearranging γ genes: nine germ-line variable genes belonging to two subgroups

    M.-P. LeFranc;A. Forster;R. Baer;M.A. Stinson

  • Activation of the T-cell oncogene LMO2 after gene therapy for X-linked severe combined immunodeficiency

    Matthew P. McCormack;Terence H. Rabbitts

  • The T cell leukemia LIM protein Lmo2 is necessary for adult mouse hematopoiesis

    Yoshihiro Yamada;Alan J. Warren;Claire Dobson;Alan Forster

  • Metabolism of c-myc gene products: c-myc mRNA and protein expression in the cell cycle.

    P H Rabbitts;J V Watson;A Lamond;A Forster

  • Translocations, master genes, and differences between the origins of acute and chronic leukemias.

    Terence H. Rabbitts

  • Altered nucleotide sequences of a translocated c-myc gene in Burkitt lymphoma.

    T. H. Rabbitts;P. H. Hamlyn;R. Baer

  • A map of the human immunoglobulin VH locus completed by analysis of the telomeric region of chromosome 14q

    Graham P. Cook;Ian M. Tomlinson;Gerald Walter;Harold Riethman

  • HOX11, a homeobox-containing T-cell oncogene on human chromosome 10q24.

    M A Kennedy;R Gonzalez-Sarmiento;U R Kees;F Lampert

Frequent Co-Authors

Alan Forster
Alan Forster MRC Laboratory of Molecular Biology
Marie-Paule Lefranc
Marie-Paule Lefranc University of Montpellier
Alan J. Warren
Alan J. Warren University of Cambridge
Simon E. V. Phillips
Simon E. V. Phillips University of Oxford
David Bentley
David Bentley University of Colorado Denver
Lucio Luzzatto
Lucio Luzzatto University of Florence
Isidro Sánchez-García
Isidro Sánchez-García University of Salamanca
Andrew J.H. Smith
Andrew J.H. Smith University of Edinburgh
John G. Flanagan
John G. Flanagan University of California, Berkeley
Thomas Boehm
Thomas Boehm Max Planck Society

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