D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 76 Citations 22,862 298 World Ranking 13879 National Ranking 490
Genetics D-index 73 Citations 21,258 268 World Ranking 1347 National Ranking 22

Research.com Recognitions

Awards & Achievements

2004 - Fellow of the American Academy of Arts and Sciences

Member of the Association of American Physicians

Member of the European Molecular Biology Organization (EMBO)

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • DNA

His main research concerns Immunology, Paroxysmal nocturnal hemoglobinuria, Molecular biology, Internal medicine and Gene. His Immunology research incorporates elements of Stem cell and Cell biology. His Paroxysmal nocturnal hemoglobinuria study combines topics from a wide range of disciplines, such as Hemoglobinuria, Bone marrow failure, Phenotype, CD59 and Clone.

His research in Molecular biology intersects with topics in Cell culture, Transfection, Mutation, Transcription factor and Conserved sequence. His Internal medicine research incorporates themes from Gastroenterology and Endocrinology. His Gene research is classified as research in Genetics.

His most cited work include:

  • The Complement Inhibitor Eculizumab in Paroxysmal Nocturnal Hemoglobinuria (845 citations)
  • Natural history of paroxysmal nocturnal hemoglobinuria. (648 citations)
  • Diagnosis and management of paroxysmal nocturnal hemoglobinuria. (555 citations)

What are the main themes of his work throughout his whole career to date?

Lucio Luzzatto mainly focuses on Immunology, Molecular biology, Genetics, Paroxysmal nocturnal hemoglobinuria and Gene. The concepts of his Immunology study are interwoven with issues in Haematopoiesis, Bone marrow failure, Stem cell and Clone. Lucio Luzzatto has included themes like T cell, T-cell receptor, Biochemistry, Coding region and Antibody in his Molecular biology study.

His study ties his expertise on Glucose-6-phosphate dehydrogenase together with the subject of Genetics. His study looks at the intersection of Paroxysmal nocturnal hemoglobinuria and topics like Eculizumab with Complement inhibitor. The study incorporates disciplines such as Gastroenterology and Endocrinology in addition to Internal medicine.

He most often published in these fields:

  • Immunology (27.94%)
  • Molecular biology (25.71%)
  • Genetics (20.95%)

What were the highlights of his more recent work (between 2010-2021)?

  • Immunology (27.94%)
  • Malaria (8.89%)
  • Paroxysmal nocturnal hemoglobinuria (20.00%)

In recent papers he was focusing on the following fields of study:

The scientist’s investigation covers issues in Immunology, Malaria, Paroxysmal nocturnal hemoglobinuria, Internal medicine and Eculizumab. His Immunology research is multidisciplinary, incorporating elements of Clone, Haematopoiesis, Stem cell and Germline mutation. His work in Malaria covers topics such as Pediatrics which are related to areas like Anemia.

His Paroxysmal nocturnal hemoglobinuria research integrates issues from Alternative complement pathway, Hemoglobinuria, Thrombosis, Surgery and Idiopathic aplastic anemia. His Internal medicine research includes themes of Endocrinology and Glucose-6-phosphate dehydrogenase. In his study, Genotype is inextricably linked to Complement receptor 1, which falls within the broad field of Eculizumab.

Between 2010 and 2021, his most popular works were:

  • Glucose-6-Phosphate Dehydrogenase Deficiency (182 citations)
  • G6PD deficiency: a classic example of pharmacogenetics with on-going clinical implications (114 citations)
  • Rationale for recommending a lower dose of primaquine as a Plasmodium falciparum gametocytocide in populations where G6PD deficiency is common (92 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • DNA

His primary areas of study are Immunology, Internal medicine, Endocrinology, Malaria and Primaquine. His Immunology research is multidisciplinary, relying on both Haematopoiesis, Bone marrow failure and Pharmacogenetics. His study focuses on the intersection of Haematopoiesis and fields such as Clone with connections in the field of Germline mutation.

As a member of one scientific family, he mostly works in the field of Internal medicine, focusing on Glucose-6-phosphate dehydrogenase and, on occasion, Hemoglobin. The Endocrinology study combines topics in areas such as Paroxysmal nocturnal hemoglobinuria, Hemolysis, Molecular biology and Alternative complement pathway. As a part of the same scientific study, Lucio Luzzatto usually deals with the Malaria, concentrating on Haemolysis and frequently concerns with Drug.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

The complement inhibitor eculizumab in paroxysmal nocturnal hemoglobinuria.

Peter Hillmen;Neal S. Young;Jörg Schubert;Robert A. Brodsky.
The New England Journal of Medicine (2006)

1258 Citations

Natural history of paroxysmal nocturnal hemoglobinuria.

Peter Hillmen;S.M. Lewis;Monica Bessler;Lucio Luzzatto.
The New England Journal of Medicine (1995)

1017 Citations

Diagnosis and management of paroxysmal nocturnal hemoglobinuria.

Charles Parker;Mitsuhiro Omine;Stephen Richards;Jun-Ichi Nishimura.
Blood (2005)

979 Citations

Targeted disruption of the housekeeping gene encoding glucose 6-phosphate dehydrogenase (G6PD): G6PD is dispensable for pentose synthesis but essential for defense against oxidative stress

P.P. Pandolfi;F. Sonati;R. Rivi;P. Mason.
The EMBO Journal (1995)

750 Citations

Therapeutic haemoglobin synthesis in β-thalassaemic mice expressing lentivirus-encoded human β-globin

Chad May;Stefano Rivella;John Callegari;Glenn Heller.
Nature (2000)

693 Citations

Effect of the complement inhibitor eculizumab on thromboembolism in patients with paroxysmal nocturnal hemoglobinuria.

Peter Hillmen;Petra Muus;Ulrich Dührsen;Antonio M. Risitano.
Blood (2007)

628 Citations

Ex vivo enrichment of mesenchymal cell progenitors by fibroblast growth factor 2.

Giordano Bianchi;Andrea Banfi;Maddalena Mastrogiacomo;Rosario Notaro.
Experimental Cell Research (2003)

519 Citations

Glucose-6-phosphate dehydrogenase deficiency

Mark Layton;Manoj Ramachandran;Denise O'Shaughnessy;Lucio Luzzatto.
Current Paediatrics (1995)

473 Citations

Clonal populations of hematopoietic cells with paroxysmal nocturnal hemoglobinuria genotype and phenotype are present in normal individuals.

David J. Araten;Khedoudja Nafa;Kriangsak Pakdeesuwan;Lucio Luzzatto.
Proceedings of the National Academy of Sciences of the United States of America (1999)

449 Citations

Paroxysmal nocturnal haemoglobinuria (PNH) is caused by somatic mutations in the PIG-A gene.

M Bessler;P J Mason;P Hillmen;T Miyata.
The EMBO Journal (1994)

429 Citations

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