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Eisuke Mekada

Eisuke Mekada

Osaka University
Japan

D-Index & Metrics

Biology and Biochemistry

D-Index
61
Citations
14153
World Ranking
11293
National Ranking
775

Eisuke Mekada publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Eisuke Mekada sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 413 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 848 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 949 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 840 scientists 207–216 publications: 733 scientists 217–226 publications: 708 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 417 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 196 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 59 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 143 publications — 23rd percentile

23% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Eisuke Mekada D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Eisuke Mekada sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 316 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 899 scientists 52–53 D-Index: 1,025 scientists 54–55 D-Index: 1,149 scientists 56–57 D-Index: 1,235 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,162 scientists 62–63 D-Index: 1,130 scientists 64–65 D-Index: 1,031 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 714 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 71 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 61 D-Index — 44th percentile

44% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Eisuke Mekada is affiliated with Osaka University in Japan and focuses their research primarily in the field of Medicine, with significant contributions to Infectious Diseases and Immunology, along with work related to Surgery, Cardiology and Cardiovascular Medicine, and Hepatology.

The scientist's work addresses a range of topics including viral gastroenteritis research and epidemiology, IL-33, ST2, and innate lymphoid cell (ILC) pathways, eosinophilic esophagitis, immune cell function and interaction, viral infections and immunology research, hepatitis viruses studies and epidemiology, and animal virus infections studies.

Recent publications illustrate a concentration on immune responses and viral transmission mechanisms. These include:

  • Group 3 innate lymphoid cells produce the growth factor HB-EGF to protect the intestine from TNF-mediated inflammation (2022, Nature Immunology)
  • Norovirus transmission mediated by asymptomatic family members in households (2020, PLoS ONE)
  • Spread of genetically similar noroviruses in Bangkok, Thailand, through symptomatic and asymptomatic individuals (2021, Heliyon)
  • Identification of GII.14[P7] norovirus and its genomic mutations from a case of long-term infection in a post-symptomatic individual (2020, Infection Genetics and Evolution)

Frequent co-authors collaborating closely with Eisuke Mekada include Benjarat Phattanawiboon, Nutthawan Nonthabenjawan, Patcharaporn Boonyos, Worakarn Towayunanta, and Kobkool Chuntrakool.

Publications have appeared in journals such as Nature Immunology, PLoS ONE, Heliyon, and Infection Genetics and Evolution, each featured as frequent venues for their research dissemination.

Best Publications

  • One molecule of diphtheria toxin fragment A introduced into a cell can kill the cell.

    Masaru Yamaizumi;Eisuke Mekada;Tsuyoshi Uchida;Yoshio Okada

  • Requirement of CD9 on the egg plasma membrane for fertilization.

    Kenji Miyado;Gen Yamada;Shuichi Yamada;Hidetoshi Hasuwa

  • A metalloprotease-disintegrin, MDC9/meltrin-gamma/ADAM9 and PKCdelta are involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor.

    Yasushi Izumi;Michinari Hirata;Hidetoshi Hasuwa;Ryo Iwamoto;Ryo Iwamoto

  • Diphtheria toxin receptor-mediated conditional and targeted cell ablation in transgenic mice

    Michiko Saito;Takao Iwawaki;Choji Taya;Hiromichi Yonekawa

  • Diphtheria Toxin Binds to the Epidermal Growth Factor (EGF)-like Domain of Human Heparin-binding EGF-like Growth Factor/Diphtheria Toxin Receptor and Inhibits Specifically Its Mitogenic Activity

    Toshihide Mitamura;Shigeki Higashiyama;Naoyuki Taniguchi;Michael Klagsbrun

  • Heparin-binding EGF-like growth factor and ErbB signaling is essential for heart function

    Ryo Iwamoto;Satoru Yamazaki;Masanori Asakura;Seiji Takashima

  • Heparin-binding EGF-like growth factor accelerates keratinocyte migration and skin wound healing

    Yuji Shirakata;Rina Kimura;Daisuke Nanba;Ryo Iwamoto

  • Heparin-binding EGF-like growth factor, which acts as the diphtheria toxin receptor, forms a complex with membrane protein DRAP27/CD9, which up-regulates functional receptors and diphtheria toxin sensitivity

    R. Iwamoto;S. Higashiyama;T. Mitamura;N. Taniguchi

  • The membrane protein CD9/DRAP 27 potentiates the juxtacrine growth factor activity of the membrane-anchored heparin-binding EGF-like growth factor.

    S Higashiyama;R Iwamoto;K Goishi;G Raab

  • Membrane-anchored heparin-binding EGF-like growth factor (HB-EGF) and diphtheria toxin receptor-associated protein (DRAP27)/CD9 form a complex with integrin alpha 3 beta 1 at cell-cell contact sites.

    Kuniaki Nakamura;Ryo Iwamoto;Eisuke Mekada

  • Phorbol ester induces the rapid processing of cell surface heparin-binding EGF-like growth factor: conversion from juxtacrine to paracrine growth factor activity.

    K Goishi;S Higashiyama;M Klagsbrun;N Nakano

  • Heparin-binding EGF-like growth factor: a juxtacrine growth factor.

    Ryo Iwamoto;Eisuke Mekada

  • Heparin-binding EGF-like growth factor is a promising target for ovarian cancer therapy

    Shingo Miyamoto;Michinari Hirata;Ayano Yamazaki;Takuya Kageyama

  • Ligand-independent Dimer Formation of Epidermal Growth Factor Receptor (EGFR) Is a Step Separable from Ligand-induced EGFR Signaling

    Xiaochun Yu;Kailash D. Sharma;Tsuyoshi Takahashi;Ryo Iwamoto

  • The cytotoxic action of diphtheria toxin and its degradation in intact Vero cells are inhibited by bafilomycin A1, a specific inhibitor of vacuolar-type H(+)-ATPase.

    T Umata;Y Moriyama;M Futai;E Mekada

  • Tetraspanins CD9 and CD81 function to prevent the fusion of mononuclear phagocytes

    Yoshito Takeda;Isao Tachibana;Kenji Miyado;Masatoshi Kobayashi

  • Clinical significance of heparin-binding epidermal growth factor- like growth factor and a disintegrin and metalloprotease 17 expression in human ovarian cancer

    Yoshihiro Tanaka;Shingo Miyamoto;Satoshi O. Suzuki;Eiji Oki

  • The fusing ability of sperm is bestowed by CD9-containing vesicles released from eggs in mice

    Kenji Miyado;Keiichi Yoshida;Kazuo Yamagata;Keiichi Sakakibara

  • Mice with defects in HB-EGF ectodomain shedding show severe developmental abnormalities

    Satoru Yamazaki;Ryo Iwamoto;Kazuko Saeki;Masanori Asakura

  • Heparin-binding epidermal growth factor-like growth factor as a novel targeting molecule for cancer therapy

    Shingo Miyamoto;Hiroshi Yagi;Fusanori Yotsumoto;Tatsuhiko Kawarabayashi

Frequent Co-Authors

Shigeki Higashiyama
Shigeki Higashiyama Ehime University
Yoshio Okada
Yoshio Okada Kobe Gakuin University
Michael Klagsbrun
Michael Klagsbrun Boston Children's Hospital
Masafumi Kitakaze
Masafumi Kitakaze Southern Medical University
Naoyuki Taniguchi
Naoyuki Taniguchi Osaka University
Masaru Okabe
Masaru Okabe Osaka University
Masatsugu Hori
Masatsugu Hori Osaka University
Koji Hashimoto
Koji Hashimoto Ehime University
Naoto Oku
Naoto Oku University of Shizuoka
Yoshiharu Matsuura
Yoshiharu Matsuura Osaka University

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Best Scientists Citing Eisuke Mekada

Shigeki Higashiyama

Shigeki Higashiyama

Ehime University

Publications: 88

Eric Rubinstein

Eric Rubinstein

Sorbonne University

Publications: 46

Claude Boucheix

Claude Boucheix

University of Paris-Saclay

Publications: 45

Martin E. Hemler

Martin E. Hemler

Harvard University

Publications: 41

Carl P. Blobel

Carl P. Blobel

Cornell University

Publications: 34

Kenji Kohno

Kenji Kohno

Nara Institute of Science and Technology

Publications: 31

Francisco Sánchez-Madrid

Francisco Sánchez-Madrid

Autonomous University of Madrid

Publications: 27

Raymond C. Harris

Raymond C. Harris

Vanderbilt University Medical Center

Publications: 27

Kirsten Sandvig

Kirsten Sandvig

Oslo University Hospital

Publications: 27

Ira Pastan

Ira Pastan

Center for Cancer Research

Publications: 26

María Yáñez-Mó

María Yáñez-Mó

Spanish National Research Council

Publications: 25

Peter J. Dempsey

Peter J. Dempsey

University of Colorado Denver

Publications: 23

Naoyuki Taniguchi

Naoyuki Taniguchi

Osaka University

Publications: 23

John R. Murphy

John R. Murphy

Johns Hopkins University

Publications: 22

Daniel A. Vallera

Daniel A. Vallera

University of Minnesota

Publications: 22

Masaru Okabe

Masaru Okabe

Osaka University

Publications: 21

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