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Genetics

D-Index
95
Citations
32922
World Ranking
900
National Ranking
126

Research.com Recognitions

  • 2015 - Fellow of the Royal Society, United Kingdom

Overview

Laurence D. Hurst is affiliated with the University of Bath in the United Kingdom. Their research primarily focuses on biochemistry, genetics, and molecular biology, with a substantial number of publications in molecular biology, genetics, and plant science. Their work extends into infectious diseases as well as sociology and political science.

Their research covers a variety of topics including:

  • RNA and protein synthesis mechanisms
  • Genomics and phylogenetic studies
  • RNA modifications and cancer
  • Chromosomal and genetic variations
  • RNA research and splicing
  • CRISPR and genetic engineering
  • Evolution and genetic dynamics

Some of their recent papers include:

  • "Active and repressed biosynthetic gene clusters have spatially distinct chromosome states", 2020, Proceedings of the National Academy of Sciences
  • "Codon Usage and Splicing Jointly Influence mRNA Localization", 2020, Cell Systems
  • "Evidence for Strong Mutation Bias toward, and Selection against, U Content in SARS-CoV-2: Implications for Vaccine Design", 2020, Molecular Biology and Evolution
  • "Dynamic reprogramming of H3K9me3 at hominoid-specific retrotransposons during human preimplantation development", 2022, Cell stem cell
  • "Causes and Consequences of Purifying Selection on SARS-CoV-2", 2021, Genome Biology and Evolution

Frequent co-authors who have collaborated extensively with Laurence D. Hurst are:

  • Alexander T Ho (11 co-authored works)
  • Grzegorz Kudla (8 co-authored works)
  • Zsuzsanna Izsvák (8 co-authored works)
  • Christine Mordstein (7 co-authored works)
  • Atahualpa Castillo-Morales (6 co-authored works)

Their publications often appear in venues such as:

  • Molecular Biology and Evolution (6 publications)
  • PLoS Biology (6 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (6 publications)
  • Genome Biology and Evolution (5 publications)
  • Zenodo (CERN European Organization for Nuclear Research) (4 publications)

Laurence D. Hurst has also contributed to academic literature through book publication. A forthcoming book titled The Evolution of Imperfection is expected in 2025, published by Princeton University Press.

Among distinctions, they were recognized as a Fellow of the Royal Society in the United Kingdom in 2015.

Best Publications

  • Complete genomes of two clinical Staphylococcus aureus strains: Evidence for the rapid evolution of virulence and drug resistance

    Matthew T. G. Holden;Edward J. Feil;Jodi A. Lindsay;Sharon J. Peacock

  • The Ka/Ks ratio: diagnosing the form of sequence evolution.

    Laurence D Hurst

  • Dosage sensitivity and the evolution of gene families in yeast

    Balázs Papp;Csaba Pál;Csaba Pál;Laurence D. Hurst

  • Hearing silence: non-neutral evolution at synonymous sites in mammals

    J. V. Chamary;Joanna L. Parmley;Laurence D. Hurst

  • The evolutionary dynamics of eukaryotic gene order

    Laurence D. Hurst;Csaba Pál;Csaba Pál;Martin J. Lercher

  • Highly expressed genes in yeast evolve slowly

    Csaba Pál;Balázs Papp;Laurence D. Hurst

  • Clustering of housekeeping genes provides a unified model of gene order in the human genome.

    Martin J. Lercher;Araxi O. Urrutia;Laurence D. Hurst

  • The Genetic Code Is One in a Million

    Stephen J. Freeland;Laurence D. Hurst

  • The evolution of isochores.

    Adam Eyre-Walker;Laurence D. Hurst

  • Comparisons of dN/dS are time dependent for closely related bacterial genomes.

    Eduardo P.C. Rocha;John Maynard Smith;Laurence D. Hurst;Matthew T.G. Holden

  • Primate-specific endogenous retrovirus-driven transcription defines naive-like stem cells

    Jichang Wang;Gangcai Xie;Manvendra Singh;Avazeh Tashakkori Ghanbarian

  • Causes of Sex Ratio Bias May Account for Unisexual Sterility in Hybrids: - a New Explanation of Haldane's Rule and Related Phenomena

    Laurence D. Hurst;Andrew Pomiankowski

  • Recent advances in understanding of the evolution and maintenance of sex.

    Laurence D. Hurst;Joel R. Peck

  • Human SNP variability and mutation rate are higher in regions of high recombination

    Martin J Lercher;Laurence D Hurst

  • Metabolic network analysis of the causes and evolution of enzyme dispensability in yeast.

    Balázs Papp;Csaba Pál;Csaba Pál;Laurence D. Hurst

  • Positively charged residues are the major determinants of ribosomal velocity.

    Catherine A. Charneski;Laurence D. Hurst

  • A quantitative measure of error minimization in the genetic code.

    David Haig;Laurence D. Hurst

  • Do essential genes evolve slowly

    Laurence D. Hurst;Nick G.C. Smith

  • Evidence for selection on synonymous mutations affecting stability of mRNA secondary structure in mammals

    JV Chamary;Laurence D Hurst

  • Mitochondria and Male Disease

    S A Frank;L D Hurst

Frequent Co-Authors

Csaba Pál
Csaba Pál Institute of Plant Biology
Martin J. Lercher
Martin J. Lercher Heinrich Heine University Düsseldorf
Zsuzsanna Izsvák
Zsuzsanna Izsvák Max Delbrück Center for Molecular Medicine
Balázs Papp
Balázs Papp Biological Research Centre
Xiangyin Kong
Xiangyin Kong Chinese Academy of Sciences
Andrew Pomiankowski
Andrew Pomiankowski University College London
Robert N. Kelsh
Robert N. Kelsh University of Bath
Gregory D. D. Hurst
Gregory D. D. Hurst University of Liverpool
Edward J. Feil
Edward J. Feil University of Bath
Mike Tyers
Mike Tyers University of Montreal

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