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D-Index & Metrics

Biology and Biochemistry

D-Index
105
Citations
64124
World Ranking
1173
National Ranking
29

Overview

Mike Tyers is affiliated with the University of Montreal in Canada and works primarily in the fields of Biochemistry, Genetics, and Molecular Biology. Their research output includes 114 publications concentrated mainly in molecular biology, genetics, infectious diseases, cell biology, and oncology.

The scientist's recent papers include the following:

  • The BioGRID database: A comprehensive biomedical resource of curated protein, genetic, and chemical interactions (2020), published in Protein Science
  • PRMT5 inhibition disrupts splicing and stemness in glioblastoma (2021), published in Nature Communications
  • Metabolic Regulation of the Epigenome Drives Lethal Infantile Ependymoma (2020), published in Cell
  • Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response (2020), published in Nature Communications
  • UM171 Preserves Epigenetic Marks that Are Reduced in Ex Vivo Culture of Human HSCs via Potentiation of the CLR3-KBTBD4 Complex (2021), published in Cell stem cell

Mike Tyers collaborates frequently with several coauthors, including:

  • Jasmin Coulombe-Huntington
  • Sylvain Tollis
  • Thierry Bertomeu
  • Catherine A. Royer
  • Almer M. van der Sloot

The scientist publishes work mainly in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Biophysical Journal
  • arXiv (Cornell University)
  • Nature Communications
  • The Journal of Cell Biology

Their research topics span several areas, including:

  • Fungal and yeast genetics research
  • Ubiquitin and proteasome pathways
  • Protein Degradation and Inhibitors
  • CRISPR and Genetic Engineering
  • RNA Research and Splicing
  • Genomics and Chromatin Dynamics
  • Cancer-related gene regulation

Best Publications

  • Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry

    Yuen Ho;Albrecht Gruhler;Adrian Heilbut;Gary D Bader;Gary D Bader

  • BioGRID: a general repository for interaction datasets

    Chris Stark;Bobby-Joe Breitkreutz;Teresa Reguly;Lorrie Boucher

  • Systematic Genetic Analysis with Ordered Arrays of Yeast Deletion Mutants

    Amy Hin Yan Tong;Marie Evangelista;Ainslie B. Parsons;Hong Xu

  • The BioGRID interaction database: 2015 update

    Andrew Chatr-aryamontri;Bobby-Joe Breitkreutz;Rose Oughtred;Lorrie Boucher

  • The BioGRID interaction database: 2017 update

    Andrew Chatr-aryamontri;Rose Oughtred;Lorrie Boucher;Jennifer M. Rust

  • The BioGRID database: A comprehensive biomedical resource of curated protein, genetic, and chemical interactions.

    Rose Oughtred;Jennifer Rust;Christie Chang;Bobby-Joe Breitkreutz

  • From genomics to proteomics

    Mike Tyers;Matthias Mann

  • F-Box Proteins Are Receptors that Recruit Phosphorylated Substrates to the SCF Ubiquitin-Ligase Complex

    Dorota Skowyra;Karen L Craig;Mike Tyers;Stephen J Elledge

  • The BioGRID interaction database: 2019 update

    Rose Oughtred;Chris Stark;Bobby-Joe Breitkreutz;Jennifer M. Rust

  • Global Analysis of Protein Phosphorylation in Yeast

    Jason Ptacek;Geeta Devgan;Gregory Michaud;Heng Zhu

  • The Chemical Genomic Portrait of Yeast: Uncovering a Phenotype for All Genes

    Maureen E. Hillenmeyer;Eula Fung;Jan Wildenhain;Sarah E. Pierce

  • Signaling and Circuitry of Multiple MAPK Pathways Revealed by a Matrix of Global Gene Expression Profiles

    Christopher J. Roberts;Bryce Nelson;Matthew J. Marton;Roland Stoughton

  • The BioGRID Interaction Database: 2011 update

    Chris Stark;Bobby-Joe Breitkreutz;Andrew Chatr-aryamontri;Lorrie Boucher

  • The BioGRID interaction database: 2013 update

    Andrew Chatr-aryamontri;Bobby-Joe Breitkreutz;Sven Heinicke;Lorrie Boucher

  • Systematic identification of pathways that couple cell growth and division in yeast.

    Paul Jorgensen;Joy L. Nishikawa;Joy L. Nishikawa;Bobby-Joe Breitkreutz;Mike Tyers;Mike Tyers

  • Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replication

    Piers Nash;Xiaojing Tang;Stephen Orlicky;Qinghua Chen

  • The BioGRID Interaction Database: 2008 update

    Bobby-Joe Breitkreutz;Chris Stark;Teresa Reguly;Lorrie Boucher

  • SAINT: probabilistic scoring of affinity purification-mass spectrometry data

    Hyungwon Choi;Brett Larsen;Zhen Yuan Lin;Ashton Breitkreutz

  • BoxPlotR: a web tool for generation of box plots

    Michaela Spitzer;Jan Wildenhain;Juri Rappsilber;Mike Tyers

  • A global protein kinase and phosphatase interaction network in yeast.

    Ashton Breitkreutz;Hyungwon Choi;Jeffrey R. Sharom;Lorrie Boucher

Frequent Co-Authors

Frank Sicheri
Frank Sicheri Lunenfeld-Tanenbaum Research Institute
Andrew Chatr-aryamontri
Andrew Chatr-aryamontri University of Montreal
Anne-Claude Gingras
Anne-Claude Gingras Lunenfeld-Tanenbaum Research Institute
Kara Dolinski
Kara Dolinski Princeton University
Gary D. Bader
Gary D. Bader University of Toronto
Tony Pawson
Tony Pawson University of Toronto
Daniel Durocher
Daniel Durocher Lunenfeld-Tanenbaum Research Institute
Cheryl H. Arrowsmith
Cheryl H. Arrowsmith Structural Genomics Consortium
Catherine A. Royer
Catherine A. Royer Rensselaer Polytechnic Institute
Peter B. Dirks
Peter B. Dirks University of Toronto

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