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Genetics
Canada
2024

D-Index & Metrics

Genetics

D-Index
116
Citations
56191
World Ranking
442
National Ranking
15

Research.com Recognitions

  • 2024 - Research.com Genetics in Canada Leader Award
  • 2023 - Research.com Genetics in Canada Leader Award
  • 2010 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 2005 - Fellow of the Royal Society of Canada Academy of Science

Overview

Charles Boone is affiliated with the University of Toronto in Canada and has contributed extensively to the field of Biochemistry, Genetics, and Molecular Biology, particularly focusing on molecular biology within this broad category. Their research encompasses multiple subfields, including molecular biology, epidemiology, infectious diseases, biophysics, and plant science.

The scientist's work covers diverse topics related to fungal and yeast genetics research, bioinformatics and genomic networks, RNA and protein synthesis mechanisms, CRISPR and genetic engineering, RNA modifications and cancer, single-cell and spatial transcriptomics, and RNA research and splicing.

Charles Boone has published a number of notable papers, including:

  • Threats Posed by the Fungal Kingdom to Humans, Wildlife, and Agriculture, 2020, mBio
  • Retention of duplicated genes in evolution, 2021, Trends in Genetics
  • Exploring whole-genome duplicate gene retention with complex genetic interaction analysis, 2020, Science
  • Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism, 2020, Nature Metabolism
  • Context-dependent regulation of ferroptosis sensitivity, 2022, Cell Chemical Biology

The scientist frequently publishes in venues such as bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, Molecular Systems Biology, G3 Genes Genomes Genetics, and UNC Libraries.

Collaborations form a significant aspect of Charles Boone's research activity. Frequent coauthors include Brenda Andrews, Chad L. Myers, Michael Costanzo, Yoko Yashiroda, and Jason Moffat.

Throughout their career, Charles Boone has been recognized with awards including the Fellow of the Royal Society of Canada, under the Academy of Science, awarded in 2005, and the Fellow of the American Association for the Advancement of Science (AAAS) in 2010.

Best Publications

  • The genetic landscape of a cell.

    Michael Costanzo;Anastasia Baryshnikova;Jeremy Bellay;Yungil Kim

  • Global Mapping of the Yeast Genetic Interaction Network

    Amy Hin Yan Tong;Guillaume Lesage;Gary D. Bader;Huiming Ding

  • Systematic Genetic Analysis with Ordered Arrays of Yeast Deletion Mutants

    Amy Hin Yan Tong;Marie Evangelista;Ainslie B. Parsons;Hong Xu

  • High-Quality Binary Protein Interaction Map of the Yeast Interactome Network

    Haiyuan Yu;Pascal Braun;Muhammed A Yildirim;Irma Lemmens

  • A global genetic interaction network maps a wiring diagram of cellular function

    Michael Costanzo;Benjamin VanderSluis;Elizabeth N. Koch;Anastasia Baryshnikova

  • Signaling and Circuitry of Multiple MAPK Pathways Revealed by a Matrix of Global Gene Expression Profiles

    Christopher J. Roberts;Bryce Nelson;Matthew J. Marton;Roland Stoughton

  • Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map

    Sean R. Collins;Kyle M. Miller;Nancy L. Maas;Assen Roguev

  • An empirical framework for binary interactome mapping

    Kavitha Venkatesan;Kavitha Venkatesan;Jean François Rual;Alexei Vazquez;Alexei Vazquez;Ulrich Stelzl

  • Exploration of the Function and Organization of the Yeast Early Secretory Pathway through an Epistatic Miniarray Profile

    Maya Schuldiner;Sean R. Collins;Natalie J. Thompson;Vladimir Denic

  • Cotranscriptional set2 methylation of histone H3 lysine 36 recruits a repressive Rpd3 complex.

    Michael Christopher Keogh;Siavash K. Kurdistani;Stephanie A. Morris;Seong Hoon Ahn

  • Role of Formins in Actin Assembly: Nucleation and Barbed-End Association

    David Pruyne;Marie Evangelista;Changsong Yang;Erfei Bi

  • Navigating the Chaperone Network: An Integrative Map of Physical and Genetic Interactions Mediated by the Hsp90 Chaperone

    Rongmin Zhao;Mike Davey;Ya-Chieh Hsu;Pia Kaplanek

  • A Combined Experimental and Computational Strategy to Define Protein Interaction Networks for Peptide Recognition Modules

    Amy Hin Yan Tong;Becky Drees;Giuliano Nardelli;Gary D. Bader

  • Methylation of histone H3 by Set2 in Saccharomyces cerevisiae is linked to transcriptional elongation by RNA polymerase II.

    Nevan J. Krogan;Minkyu Kim;Amy Tong;Ashkan Golshani

  • Bni1p, a Yeast Formin Linking Cdc42p and the Actin Cytoskeleton During Polarized Morphogenesis

    Marie Evangelista;Kelly Blundell;Mark S. Longtine;Clinton J. Chow

  • Mapping Pathways and Phenotypes by Systematic Gene Overexpression

    Richelle Sopko;Dongqing Huang;Nicolle Preston;Gordon Chua

  • Integration of chemical-genetic and genetic interaction data links bioactive compounds to cellular target pathways

    Ainslie B Parsons;Renée L Brost;Huiming Ding;Zhijian Li

  • Exploring genetic interactions and networks with yeast

    Charles Boone;Howard Bussey;Brenda J. Andrews

  • Exploration of essential gene functions via titratable promoter alleles

    Sanie Mnaimneh;Armaity P Davierwala;Jennifer Haynes;Jason Moffat

  • Global Mapping of the Yeast Genetic Interaction Network: Discovering Gene and Drug Function

    Amy Tong;Guillaume Lesage;Ainslie Parsons;Brenda Andrews

Frequent Co-Authors

Brenda J. Andrews
Brenda J. Andrews University of Toronto
Michael Costanzo
Michael Costanzo University of Toronto
Chad L. Myers
Chad L. Myers University of Minnesota
Amy Hin Yan Tong
Amy Hin Yan Tong University of Toronto
Grant W. Brown
Grant W. Brown University of Toronto
Gary D. Bader
Gary D. Bader University of Toronto
Corey Nislow
Corey Nislow University of British Columbia
Minoru Yoshida
Minoru Yoshida University of Tokyo
Frederick P. Roth
Frederick P. Roth Lunenfeld-Tanenbaum Research Institute
Yoshikazu Ohya
Yoshikazu Ohya University of Tokyo

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