World's Best Scientists 2026 revealed!
Jonathan S. Weissman

Jonathan S. Weissman

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Molecular Biology
USA
2026
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Genetics
USA
2024

D-Index & Metrics

Molecular Biology

D-Index
164
Citations
136637
World Ranking
53
National Ranking
36

Research.com Recognitions

  • 2026 - Research.com Molecular Biology in United States Leader Award
  • 2025 - Research.com Molecular Biology in United States Leader Award
  • 2024 - Research.com Genetics in United States Leader Award
  • 2023 - Research.com Genetics in United States Leader Award

Overview

Jonathan S. Weissman is affiliated with MIT in the United States and has made contributions primarily in the field of Biochemistry, Genetics and Molecular Biology. Their research spans several subfields, including Molecular Biology, Cancer Research, Oncology, Biophysics, and Immunology.

The scientist's work covers a range of topics such as CRISPR and Genetic Engineering, Single-cell and spatial transcriptomics, RNA and protein synthesis mechanisms, Cancer Genomics and Diagnostics, RNA Research and Splicing, RNA modifications and cancer, and Cell Image Analysis Techniques.

Recent publications by Jonathan S. Weissman include:

  • Enhanced prime editing systems by manipulating cellular determinants of editing outcomes, 2021, Cell
  • Genome-wide programmable transcriptional memory by CRISPR-based epigenome editing, 2021, Cell
  • Therapy-Induced Evolution of Human Lung Cancer Revealed by Single-Cell RNA Sequencing, 2020, Cell
  • Pervasive functional translation of noncanonical human open reading frames, 2020, Science
  • OpenCell: Endogenous tagging for the cartography of human cellular organization, 2022, Science

Frequent co-authors collaborating with Weissman include:

  • Joseph M. Replogle
  • Marco Jost
  • Jeffrey A. Hussmann
  • Dian Yang
  • Nir Yosef

Jonathan S. Weissman has published extensively across venues such as bioRxiv (Cold Spring Harbor Laboratory), Cell, Nature Biotechnology, Science, and Zenodo (CERN European Organization for Nuclear Research). The distribution of publications includes 43 papers in bioRxiv, 13 in Cell, 10 in Nature Biotechnology, 7 in Science, and 7 in Zenodo.

Best Publications

  • Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression.

    Lei S. Qi;Matthew H. Larson;Luke A. Gilbert;Jennifer A. Doudna

  • Global analysis of protein localization in budding yeast

    Won-Ki Huh;James V. Falvo;Luke C. Gerke;Adam S. Carroll

  • Global analysis of protein expression in yeast

    Sina Ghaemmaghami;Won-Ki Huh;Kiowa Bower;Russell W. Howson

  • Mammalian microRNAs predominantly act to decrease target mRNA levels

    Huili Guo;Nicholas T. Ingolia;Nicholas T. Ingolia;Jonathan S. Weissman;Jonathan S. Weissman;David P. Bartel

  • Genome-Wide Analysis in Vivo of Translation with Nucleotide Resolution Using Ribosome Profiling

    Nicholas T. Ingolia;Sina Ghaemmaghami;John R. S. Newman;Jonathan S. Weissman

  • CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes

    Luke A. Gilbert;Matthew H. Larson;Leonardo Morsut;Zairan Liu

  • Global landscape of protein complexes in the yeast Saccharomyces cerevisiae

    Nevan J. Krogan;Gerard Cagney;Gerard Cagney;Haiyuan Yu;Gouqing Zhong

  • Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation

    Luke A. Gilbert;Max A. Horlbeck;Britt Adamson;Jacqueline E. Villalta

  • Ribosome Profiling of Mouse Embryonic Stem Cells Reveals the Complexity and Dynamics of Mammalian Proteomes

    Nicholas T. Ingolia;Liana F. Lareau;Jonathan S. Weissman

  • Functional and Genomic Analyses Reveal an Essential Coordination between the Unfolded Protein Response and ER-Associated Degradation

    Kevin J Travers;Christopher K Patil;Lisa Wodicka;David J Lockhart

  • Dynamic Imaging of Genomic Loci in Living Human Cells by an Optimized CRISPR/Cas System

    Baohui Chen;Luke A. Gilbert;Beth A. Cimini;Joerg Schnitzbauer

  • Molecular Chaperones and Protein Quality Control

    Bernd Bukau;Jonathan Weissman;Arthur Horwich;Arthur Horwich

  • Perturb-Seq: Dissecting Molecular Circuits with Scalable Single-Cell RNA Profiling of Pooled Genetic Screens

    Atray Dixit;Atray Dixit;Oren Parnas;Biyu Li;Jenny Chen;Jenny Chen

  • Single-cell proteomic analysis of S. cerevisiae reveals the architecture of biological noise

    John R. S. Newman;Sina Ghaemmaghami;Sina Ghaemmaghami;Jan Ihmels;David K. Breslow

  • A Protein-Tagging System for Signal Amplification in Gene Expression and Fluorescence Imaging

    Marvin E. Tanenbaum;Luke A. Gilbert;Lei S. Qi;Jonathan S. Weissman

  • The Human Cell Atlas

    Aviv Regev;Aviv Regev;Aviv Regev;Sarah A Teichmann;Sarah A Teichmann;Sarah A Teichmann;Eric S Lander;Eric S Lander;Eric S Lander;Ido Amit

  • Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response.

    Julie Hollien;Jonathan S. Weissman

  • Quantifying Absolute Protein Synthesis Rates Reveals Principles Underlying Allocation of Cellular Resources

    Gene Wei Li;David Burkhardt;Carol Gross;Jonathan S. Weissman

  • The translational landscape of mTOR signalling steers cancer initiation and metastasis

    Andrew C. Hsieh;Yi Liu;Merritt P. Edlind;Nicholas T. Ingolia

  • An ER-Mitochondria Tethering Complex Revealed by a Synthetic Biology Screen

    Benoît Kornmann;Erin Currie;Sean R. Collins;Maya Schuldiner

Frequent Co-Authors

Martin Kampmann
Martin Kampmann University of California, San Francisco
Luke A. Gilbert
Luke A. Gilbert University of California, San Francisco
Nevan J. Krogan
Nevan J. Krogan University of California, San Francisco
Peter Walter
Peter Walter University of California, San Francisco
Aviv Regev
Aviv Regev Genentech
Nicholas T. Ingolia
Nicholas T. Ingolia University of California, Berkeley
Michael C. Bassik
Michael C. Bassik Stanford University
Eric S. Lander
Eric S. Lander Broad Institute
Lei S. Qi
Lei S. Qi Stanford University
Carol A. Gross
Carol A. Gross University of California, San Francisco

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