Michael C. Bassik

Overview

Best Publications

• Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation

  Luke A. Gilbert;Max A. Horlbeck;Britt Adamson;Jacqueline E. Villalta

  2981
  Citations

• The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis.

  Kirill Bersuker;Joseph M. Hendricks;Zhipeng Li;Leslie Magtanong

  2481
  Citations

• Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics.

  Anthony Letai;Michael C. Bassik;Loren D. Walensky;Mia D. Sorcinelli

  2098
  Citations

• JNK1-Mediated Phosphorylation of Bcl-2 Regulates Starvation-Induced Autophagy

  Yongjie Wei;Sophie Pattingre;Sangita Sinha;Michael Bassik;Michael Bassik

  1529
  Citations

• Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis

  Congcong He;Michael C. Bassik;Michael C. Bassik;Viviana Moresi;Kai Sun;Kai Sun

  1301
  Citations

• Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain

  Julia Marschallinger;Julia Marschallinger;Tal Iram;Macy Zardeneta;Song E. Lee

  1255
  Citations

• CMTM6 maintains the expression of PD-L1 and regulates anti-tumour immunity

  Marian L Burr;Marian L Burr;Marian L Burr;Christina E Sparbier;Yih-Chih Chan;James C Williamson

  930
  Citations

• Proapoptotic BAX and BAK Modulate the Unfolded Protein Response by a Direct Interaction with IRE1α

  Claudio Hetz;Paula Bernasconi;Jill Fisher;Ann-Hwee Lee

  800
  Citations

• Proapoptotic BAX and BAK regulate the type 1 inositol trisphosphate receptor and calcium leak from the endoplasmic reticulum

  Scott A. Oakes;Luca Scorrano;Joseph T. Opferman;Michael C. Bassik

  531
  Citations

• Discovery of common and rare genetic risk variants for colorectal cancer

  Jeroen R. Huyghe;Stephanie A. Bien;Tabitha A. Harrison;Hyun Min Kang

  486
  Citations

• Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions

  Kyuho Han;Edwin E Jeng;Gaelen T Hess;David W Morgens

  485
  Citations

• Directed evolution using dCas9-targeted somatic hypermutation in mammalian cells

  Gaelen T Hess;Laure Frésard;Kyuho Han;Cameron H Lee

  467
  Citations

• A Systematic Mammalian Genetic Interaction Map Reveals Pathways Underlying Ricin Susceptibility

  Michael C. Bassik;Martin Kampmann;Robert Jan Lebbink;Shuyi Wang

  416
  Citations

• Systematic comparison of CRISPR/Cas9 and RNAi screens for essential genes

  David W Morgens;Richard M Deans;Amy Li;Michael C Bassik

  412
  Citations

• DNA vector chemistry: The covalent attachment of signal peptides to plasmid DNA

  Magdolna G. Sebestyén;James J. Ludtke;Michael C. Bassik;Guofeng Zhang

  363
  Citations

• Phosphorylation of BCL-2 regulates ER Ca2+ homeostasis and apoptosis

  Michael C Bassik;Luca Scorrano;Scott A Oakes;Tullio Pozzan

  352
  Citations

• Genome-scale measurement of off-target activity using Cas9 toxicity in high-throughput screens

  David W. Morgens;Michael Wainberg;Evan A. Boyle;Oana Ursu

  343
  Citations

• CD22 blockade restores homeostatic microglial phagocytosis in ageing brains

  John V. Pluvinage;Michael S. Haney;Benjamin A. H. Smith;Jerry Sun

  337
  Citations

• Lipid droplet accumulating microglia represent a dysfunctional and pro-inflammatory state in the aging brain

  Julia Marschallinger;Julia Marschallinger;Tal Iram;Macy Zardeneta;Song E. Lee

  11
  Citations

• Discovery of common and rare genetic risk variants for colorectal cancer

  Jeroen R. Huyghe;Stephanie A. Bien;Tabitha A. Harrison;Hyun Min Kang

  0
  Citations