2026 Luke A. Gilbert: Molecular Biology Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Molecular Biology	44	2881	2617	1372	1232	87	31584

Overview

Luke A. Gilbert is affiliated with the University of California, San Francisco in the United States. Their research spans broadly within the domains of Biochemistry, Genetics, and Molecular Biology, with significant focus also on Medicine. The scientist's work addresses specific subfields including Molecular Biology, Genetics, Cancer Research, Pulmonary and Respiratory Medicine, and Oncology.

Luke A. Gilbert's research topics include:

CRISPR and Genetic Engineering
RNA and protein synthesis mechanisms
Prostate Cancer Treatment and Research
Glioma Diagnosis and Treatment
Single-cell and spatial transcriptomics
Advanced biosensing and bioanalysis techniques
RNA Research and Splicing

Their recent papers illustrate the scope and progression of their research interests:

"Genome-wide programmable transcriptional memory by CRISPR-based epigenome editing," 2021, Cell
"The DNA methylation landscape of advanced prostate cancer," 2020, Nature Genetics
"A new era in functional genomics screens," 2021, Nature Reviews Genetics
"Improving prime editing with an endogenous small RNA-binding protein," 2024, Nature
"Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression," 2021, Cell

Frequent publication venues for Luke A. Gilbert include:

bioRxiv (Cold Spring Harbor Laboratory)
Cancer Research
Neuro-Oncology
Zenodo (CERN European Organization for Nuclear Research)
Nature Communications

Collaboration is evident through frequent co-authors, who appear repeatedly alongside Gilbert's contributions, and include:

Hani Goodarzi
Felix Y. Feng
David A. Quigley
David R. Raleigh
Lisa N. Chesner

Best Publications

Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression.

Lei S. Qi;Matthew H. Larson;Luke A. Gilbert;Jennifer A. Doudna

5826
Citations
CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes

Luke A. Gilbert;Matthew H. Larson;Leonardo Morsut;Zairan Liu

3985
Citations
Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation

Luke A. Gilbert;Max A. Horlbeck;Britt Adamson;Jacqueline E. Villalta

2981
Citations
Dynamic Imaging of Genomic Loci in Living Human Cells by an Optimized CRISPR/Cas System

Baohui Chen;Luke A. Gilbert;Beth A. Cimini;Joerg Schnitzbauer

2143
Citations
A Protein-Tagging System for Signal Amplification in Gene Expression and Fluorescence Imaging

Marvin E. Tanenbaum;Luke A. Gilbert;Lei S. Qi;Jonathan S. Weissman

1570
Citations
CRISPR interference (CRISPRi) for sequence-specific control of gene expression

Matthew H Larson;Luke A Gilbert;Luke A Gilbert;Xiaowo Wang;Wendell A Lim

1319
Citations
A Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response.

Britt Adamson;Thomas M. Norman;Marco Jost;Min Y. Cho

1237
Citations
Engineering Complex Synthetic Transcriptional Programs with CRISPR RNA Scaffolds

Jesse G. Zalatan;Michael E. Lee;Ricardo Almeida;Luke A. Gilbert;Luke A. Gilbert

1008
Citations
Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation

Max A. Horlbeck;Luke A. Gilbert;Jacqueline E. Villalta;Brittany Susan Adamson

783
Citations
CRISPRi-based genome-scale identification of functional long noncoding RNA loci in human cells

S. John Liu;Max A. Horlbeck;Seung Woo Cho;Harjus S. Birk

724
Citations
Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer.

David A. Quigley;Ha X. Dang;Shuang G. Zhao;Paul Lloyd

651
Citations
CRISPR Interference Efficiently Induces Specific and Reversible Gene Silencing in Human iPSCs

Mohammad A. Mandegar;Nathaniel Huebsch;Ekaterina B. Frolov;Edward Shin

497
Citations
DNA damage-mediated induction of a chemoresistant niche.

Luke A. Gilbert;Michael T. Hemann

489
Citations
Genome-wide programmable transcriptional memory by CRISPR-based epigenome editing.

James K. Nuñez;Jin Chen;Greg C. Pommier;J. Zachery Cogan

473
Citations
Versatile protein tagging in cells with split fluorescent protein.

Daichi Kamiyama;Sayaka Sekine;Benjamin Barsi-Rhyne;Jeffrey Hu

440
Citations
Nucleosomes impede Cas9 access to DNA in vivo and in vitro

Max A Horlbeck;Lea B Witkowsky;Benjamin Guglielmi;Joseph M Replogle

423
Citations
Mapping the Genetic Landscape of Human Cells

Max A. Horlbeck;Albert Xu;Min Wang;Neal K. Bennett

269
Citations
The DNA methylation landscape of advanced prostate cancer

Shuang G. Zhao;Shuang G. Zhao;William S. Chen;William S. Chen;Haolong Li;Adam Foye

265
Citations
Combined CRISPRi/a-Based Chemical Genetic Screens Reveal that Rigosertib Is a Microtubule-Destabilizing Agent.

Marco Jost;Yuwen Chen;Luke A. Gilbert;Max A. Horlbeck

227
Citations
A Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response

Britt Adamson;Thomas M. Norman;Marco Jost;Min Y. Cho

0
Citations

Frequent Co-Authors

Jonathan S. Weissman MIT

Martin Kampmann University of California, San Francisco

Lei S. Qi Stanford University

Michael T. Hemann MIT

Housheng Hansen He University of Toronto

Alan Ashworth University of California, San Francisco

Michael C. Bassik Stanford University

Bruce R. Conklin University of California, San Francisco

Michel O. Steinmetz Paul Scherrer Institute

Wendell A. Lim University of California, San Francisco

External Links

Personal website of Luke A. Gilbert

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