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D-Index & Metrics

Biology and Biochemistry

D-Index
84
Citations
30134
World Ranking
3273
National Ranking
1658

Overview

Bruce R. Conklin is affiliated with the University of California, San Francisco in the United States. Their research spans mainly across Biochemistry, Genetics and Molecular Biology, as well as Medicine. The subfields of their expertise include Molecular Biology, Biomedical Engineering, Genetics, Cardiology and Cardiovascular Medicine, and Cellular and Molecular Neuroscience.

The scholar's work covers several main topics related to biomedical and genetic research. These include:

  • CRISPR and Genetic Engineering
  • Pluripotent Stem Cells Research
  • 3D Printing in Biomedical Research
  • Congenital Heart Defects Research
  • Retinal Development and Disorders
  • Congenital Heart Disease Studies
  • Hemoglobinopathies and Related Disorders

Bruce R. Conklin has published numerous papers in a number of prominent scientific venues. Frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Stem Cell Research
  • UNC Libraries
  • Cell Reports

Notable recent publications include:

  • "SARS-CoV-2 infection of human iPSC-derived cardiac cells reflects cytopathic features in hearts of patients with COVID-19" (2021), published in Science Translational Medicine
  • "A reference human induced pluripotent stem cell line for large-scale collaborative studies" (2022), published in Cell Stem Cell
  • "Timed inhibition of CDC7 increases CRISPR-Cas9 mediated templated repair" (2020), published in Nature Communications
  • "SARS-CoV-2 infection of human iPSC-derived cardiac cells predicts novel cytopathic features in hearts of COVID-19 patients" (2020), published in bioRxiv (Cold Spring Harbor Laboratory)
  • "CRISPR off-target detection with DISCOVER-seq" (2020), published in Nature Protocols

Their frequent coauthors include:

  • Luke M. Judge
  • Juan A. Pérez-Bermejo
  • Hannah L. Watry
  • Gokul N. Ramadoss
  • Nevan J. Krogan

Best Publications

  • Integration of biological networks and gene expression data using Cytoscape

    Melissa S Cline;Michael Smoot;Ethan Cerami;Allan Kuchinsky

  • GenMAPP, a new tool for viewing and analyzing microarray data on biological pathways.

    Kam D. Dahlquist;Nathan Salomonis;Karen Vranizan;Steven C. Lawlor

  • MAPPFinder: using Gene Ontology and GenMAPP to create a global gene-expression profile from microarray data

    Scott W Doniger;Nathan Salomonis;Kam D Dahlquist;Karen Vranizan;Karen Vranizan

  • Substitution of three amino acids switches receptor specificity of Gq alpha to that of Gi alpha

    Bruce R. Conklin;Zvi Farfel;Kevin D. Lustig;David Julius

  • Hormonal stimulation of adenylyl cyclase through Gi-protein beta gamma subunits.

    Alex D. Federman;Bruce R. Conklin;Karen A. Schrader;Randall R. Reed

  • WikiPathways: Pathway Editing for the People

    Alexander R Pico;Thomas Kelder;Martijn P van Iersel;Kristina Hanspers

  • MicroRNA regulation of cell lineages in mouse and human embryonic stem cells.

    Kathryn N. Ivey;Alecia Muth;Joshua Arnold;Frank W. King

  • CRISPRi-based genome-scale identification of functional long noncoding RNA loci in human cells

    S. John Liu;Max A. Horlbeck;Seung Woo Cho;Harjus S. Birk

  • Engineered human pluripotent-stem-cell-derived intestinal tissues with a functional enteric nervous system

    Michael J. Workman;Maxime M. Mahe;Stephen Trisno;Holly M. Poling

  • Structural elements of Gα subunits that interact with Gβγ, receptors, and effectors

    Bruce R. Conklin;Henry R. Bourne

  • WikiPathways: building research communities on biological pathways

    Thomas Kelder;Martijn P. van Iersel;Kristina Hanspers;Martina Kutmon

  • Interfacing silicon nanowires with mammalian cells

    Woong Kim;Jennifer K. Ng;Miki E. Kunitake;Bruce R. Conklin

  • Human iPSC-based cardiac microphysiological system for drug screening applications.

    Anurag Mathur;Peter Loskill;Kaifeng Shao;Nathaniel Huebsch

  • CRISPR Interference Efficiently Induces Specific and Reversible Gene Silencing in Human iPSCs

    Mohammad A. Mandegar;Nathaniel Huebsch;Ekaterina B. Frolov;Edward Shin

  • Presenting and exploring biological pathways with PathVisio

    Martijn P. van Iersel;Thomas Kelder;Alexander R. Pico;Kristina Hanspers

  • Unbiased detection of CRISPR off-targets in vivo using DISCOVER-Seq.

    Beeke Wienert;Beeke Wienert;Stacia K. Wyman;Christopher D. Richardson;Charles D. Yeh

  • AltAnalyze and DomainGraph: analyzing and visualizing exon expression data

    Dorothea Emig;Nathan Salomonis;Jan Baumbach;Thomas Lengauer

  • Canonical Wnt signaling is a positive regulator of mammalian cardiac progenitors.

    Chulan Kwon;Joshua Arnold;Edward C. Hsiao;Makoto M. Taketo

  • Model for long QT syndrome type 2 using human iPS cells demonstrates arrhythmogenic characteristics in cell culture.

    Anna L. Lahti;Ville J. Kujala;Hugh Chapman;Ari-Pekka Koivisto

  • Chimeric G Proteins Allow a High-Throughput Signaling Assay of Gi-Coupled Receptors

    P. Coward;S. D. H. Chan;H. G. Wada;G. M. Humphries

Frequent Co-Authors

Nathan Salomonis
Nathan Salomonis Cincinnati Children's Hospital Medical Center
Kevin E. Healy
Kevin E. Healy University of California, Berkeley
Henry R. Bourne
Henry R. Bourne University of California, San Francisco
Deepak Srivastava
Deepak Srivastava King's College London
Shinya Yamanaka
Shinya Yamanaka Kyoto University
Alexander R. Pico
Alexander R. Pico Gladstone Institutes
Todd C. McDevitt
Todd C. McDevitt University of California, San Francisco
Katherine S. Pollard
Katherine S. Pollard University of California, San Francisco
Nevan J. Krogan
Nevan J. Krogan University of California, San Francisco

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