What is he best known for?
The fields of study he is best known for:
The scientist’s investigation covers issues in Cell biology, Receptor, Embryonic stem cell, Induced pluripotent stem cell and Genetics.
His Cell biology study frequently draws parallels with other fields, such as G alpha subunit.
To a larger extent, Bruce R. Conklin studies Biochemistry with the aim of understanding Receptor.
His studies deal with areas such as Cellular differentiation, Enteric nervous system and Neural stem cell as well as Embryonic stem cell.
His Induced pluripotent stem cell research incorporates themes from Potassium channel, Biological system, Pharmacology and Neural crest.
His G protein-coupled receptor research also works with subjects such as
- Agonist which is related to area like 5-HT5A receptor and Energy homeostasis,
- Plasma protein binding which intersects with area such as Computational biology.
His most cited work include:
- Integration of biological networks and gene expression data using Cytoscape. (1844 citations)
- GenMAPP, a new tool for viewing and analyzing microarray data on biological pathways. (896 citations)
- MAPPFinder: using Gene Ontology and GenMAPP to create a global gene-expression profile from microarray data (841 citations)
What are the main themes of his work throughout his whole career to date?
Bruce R. Conklin spends much of his time researching Cell biology, Induced pluripotent stem cell, Computational biology, Receptor and Internal medicine.
Bruce R. Conklin studies Progenitor cell which is a part of Cell biology.
His Induced pluripotent stem cell study contributes to a more complete understanding of Embryonic stem cell.
His Computational biology research includes themes of Human genome, Microarray analysis techniques, Gene, Nuclease and Genome editing.
His Receptor study often links to related topics such as Signal transduction.
His Internal medicine research focuses on Endocrinology and how it relates to Osteoblast and Transgene.
He most often published in these fields:
- Cell biology (35.51%)
- Induced pluripotent stem cell (30.84%)
- Computational biology (28.04%)
What were the highlights of his more recent work (between 2017-2021)?
- Computational biology (28.04%)
- CRISPR (19.16%)
- Genome editing (18.69%)
In recent papers he was focusing on the following fields of study:
Bruce R. Conklin mostly deals with Computational biology, CRISPR, Genome editing, Induced pluripotent stem cell and Cell biology.
His research in Computational biology intersects with topics in Epigenetics, Digital polymerase chain reaction, Disease and Proband.
His CRISPR research integrates issues from Enhancer and Promoter.
Bruce R. Conklin has researched Genome editing in several fields, including Reference genome and DNA, DNA repair.
Bruce R. Conklin has included themes like Cell, Microphthalmia-associated transcription factor, Transcription factor, Morphogenesis and Retinitis pigmentosa in his Induced pluripotent stem cell study.
His biological study spans a wide range of topics, including In vitro, CRISPR interference and Cell type.
Between 2017 and 2021, his most popular works were:
- Unbiased detection of CRISPR off-targets in vivo using DISCOVER-Seq. (131 citations)
- Unbiased detection of CRISPR off-targets in vivo using DISCOVER-Seq. (131 citations)
- Mapping cis-regulatory chromatin contacts in neural cells links neuropsychiatric disorder risk variants to target genes (54 citations)
In his most recent research, the most cited papers focused on:
Bruce R. Conklin mainly investigates Computational biology, Induced pluripotent stem cell, CRISPR, Genome editing and Cell biology.
His work carried out in the field of Computational biology brings together such families of science as Genomics, Transcription activator-like effector nuclease, Endogeny, Digital polymerase chain reaction and Allele.
His Induced pluripotent stem cell research is multidisciplinary, incorporating perspectives in Cell, Bioinformatics, Morphogenesis, Stem cell and Genetic testing.
The concepts of his CRISPR study are interwoven with issues in Enhancer, Promoter and DNA.
His work in Genome editing addresses subjects such as DNA repair, which are connected to disciplines such as Guide RNA, Chromatin immunoprecipitation and DNA damage.
His Sarcomere study, which is part of a larger body of work in Cell biology, is frequently linked to Tissue Model, bridging the gap between disciplines.
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