Henry R. Bourne

Overview

Best Publications

• The GTPase superfamily: conserved structure and molecular mechanism

  Henry R. Bourne;David A. Sanders;Frank McCormick

  4470
  Citations

• The GTPase superfamily: a conserved switch for diverse cell functions

  Henry R. Bourne;David A. Sanders;David A. Sanders;Frank McCormick

  3112
  Citations

• GTPase inhibiting mutations activate the α chain of G s and stimulate adenylyl cyclase in human pituitary tumours

  Claudia A. Landis;Susan B. Masters;Anna Spada;Ann M. Pace

  2039
  Citations

• An evolutionary trace method defines binding surfaces common to protein families

  Olivier Lichtarge;Henry R. Bourne;Fred E. Cohen

  1504
  Citations

• Modulation of Inflammation and Immunity by Cyclic AMP

  H R Bourne;L M Lichtenstein;K L Melmon;C S Henney

  1317
  Citations

• Electrical signals control wound healing through phosphatidylinositol-3-OH kinase-γ and PTEN

  Min Zhao;Bing Song;Jin Pu;Teiji Wada

  1307
  Citations

• G Proteins: A Family of Signal Transducers

  Lubert Stryer;Henry R. Bourne

  1280
  Citations

• Two G protein oncogenes in human endocrine tumors

  John Lyons;Claudia A. Landis;Claudia A. Landis;Griffith Harsh;Lucia Vallar

  1241
  Citations

• Substitution of three amino acids switches receptor specificity of Gq alpha to that of Gi alpha

  Bruce R. Conklin;Zvi Farfel;Kevin D. Lustig;David Julius

  1082
  Citations

• Polarization of Chemoattractant Receptor Signaling During Neutrophil Chemotaxis

  Guy Servant;Orion D. Weiner;Paul Herzmark;Tamás Balla

  1075
  Citations

• Hormonal stimulation of adenylyl cyclase through Gi-protein beta gamma subunits.

  Alex D. Federman;Bruce R. Conklin;Karen A. Schrader;Randall R. Reed

  883
  Citations

• Divergent signals and cytoskeletal assemblies regulate self-organizing polarity in neutrophils.

  Jingsong Xu;Fei Wang;Alexandra Van Keymeulen;Alexandra Van Keymeulen;Paul Herzmark

  819
  Citations

• How receptors talk to trimeric G proteins.

  Henry R Bourne

  804
  Citations

• Do GTPases direct membrane traffic in secretion

  Henry R. Bourne

  698
  Citations

• cAMP and beta gamma subunits of heterotrimeric G proteins stimulate the mitogen-activated protein kinase pathway in COS-7 cells.

  M Faure;T A Voyno-Yasenetskaya;H R Bourne

  678
  Citations

• Lipid modifications of trimeric G proteins.

  Philip B. Wedegaertner;Paul T. Wilson;Henry R. Bourne

  662
  Citations

• A PtdInsP(3)- and Rho GTPase-mediated positive feedback loop regulates neutrophil polarity.

  Orion D. Weiner;Paul O. Neilsen;Glenn D. Prestwich;Marc W. Kirschner

  634
  Citations

• Structural elements of Gα subunits that interact with Gβγ, receptors, and effectors

  Bruce R. Conklin;Henry R. Bourne

  621
  Citations

• Activation of the cloned muscarinic potassium channel by G protein βγ subunits

  Eitan Reuveny;Paul A. Slesinger;James Inglese;Janine M. Morales

  602
  Citations

• Rac and Cdc42 play distinct roles in regulating PI(3,4,5)P3 and polarity during neutrophil chemotaxis.

  Supriya Srinivasan;Fei Wang;Suzana Glavas;Alexander Ott

  588
  Citations