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Philip Coffino

D-Index & Metrics

Biology and Biochemistry

D-Index
63
Citations
11563
World Ranking
10418
National Ranking
4522

Philip Coffino publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Philip Coffino sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 147 publications — 25th percentile

25% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Philip Coffino D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Philip Coffino sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 63 D-Index — 49th percentile

49% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Philip Coffino is affiliated with Rockefeller University in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, with a significant focus on Medicine. The scientist's work extensively covers molecular biology and cell biology, including specialized subfields such as cancer research, radiology, nuclear medicine and imaging, and epidemiology.

The main research topics explored by Philip Coffino include:

  • Ubiquitin and proteasome pathways
  • Protein degradation and inhibitors
  • Endoplasmic reticulum stress and disease
  • Cancer, hypoxia, and metabolism
  • Autophagy in disease and therapy
  • Multiple myeloma research and treatments
  • Mitochondrial function and pathology

Philip Coffino has contributed to several notable scientific papers, including:

  • Identification of Novel Therapeutic Targets for Fibrolamellar Carcinoma Using Patient-Derived Xenografts and Direct-from-Patient Screening, 2021, Cancer Discovery
  • Allosteric coupling between α-rings of the 20S proteasome, 2020, Nature Communications
  • Targeting BCL-XL in fibrolamellar hepatocellular carcinoma, 2022, JCI Insight
  • Disruption of proteome by an oncogenic fusion kinase alters metabolism in fibrolamellar hepatocellular carcinoma, 2023, Science Advances
  • Single molecule microscopy reveals diverse actions of substrate sequences that impair ClpX AAA+ ATPase function, 2022, Journal of Biological Chemistry

The scientist frequently publishes in venues such as Cancer Research, Nature Communications, Cancer Discovery, JCI Insight, and Science Advances. Cancer Research is the most prominent among these, with multiple publications in this journal.

Philip Coffino regularly collaborates with several colleagues, including Sanford M. Simon, Barbara A. Lyons, Mahsa Shirani, Denise Ng, and Bassem Shebl.

Best Publications

  • Regulation of cellular polyamines by antizyme.

    Philip Coffino

  • Selection of a variant lymphoma cell deficient in adenylate cyclase

    Henry R. Bourne;P. Coffino;G. M. Tomkins

  • Cloning of mouse myeloma cells and detection of rare variants.

    Philip Coffino;Reuben Baumal;Reuven Laskov;Matthew D. Scharff

  • Prevention of rapid intracellular degradation of ODC by a carboxyl-terminal truncation.

    L Ghoda;T van Daalen Wetters;M Macrae;D Ascherman

  • Mutations causing charge alterations in regulatory subunits of the cAMP-dependent protein kinase of cultured S49 lymphoma cells

    Robert A. Steinberg;Patrick H. O'Farrell;Ursula Friedrich;Philip Coffino

  • Determinants of proteasome recognition of ornithine decarboxylase, a ubiquitin-independent substrate

    Mingsheng Zhang;Cecile M. Pickart;Philip Coffino

  • Agonist-specific refractoriness induced by isoproterenol. Studies with mutant cells.

    M Shear;P A Insel;K L Melmon;P Coffino

  • Ubiquitin-independent proteasomal degradation

    Jenny Erales;Philip Coffino

  • High-risk human papillomavirus E6 protein has two distinct binding sites within p53, of which only one determines degradation.

    X Li;P Coffino

  • Molecular cloning and expression of the mouse ornithine decarboxylase gene

    Lisa McConlogue;Madhu Gupta;Lily Wu;Philip Coffino

  • Rate of Somatic Mutation in Immunoglobulin Production by Mouse Myeloma Cells

    Philip Coffino;Matthew D. Scharff

  • Ubistatins Inhibit Proteasome-Dependent Degradation by Binding the Ubiquitin Chain

    Rati Verma;Noel R. Peters;Mariapina D'Onofrio;Gregory P. Tochtrop

  • Cloning and sequencing of the ornithine decarboxylase gene from Trypanosoma brucei. Implications for enzyme turnover and selective difluoromethylornithine inhibition.

    M A Phillips;M A Phillips;P Coffino;C C Wang

  • Sequestered end products and enzyme regulation: the case of ornithine decarboxylase.

    Rowland H. Davis;David R. Morris;Philip Coffino

  • Degradation of ornithine decarboxylase: exposure of the C-terminal target by a polyamine-inducible inhibitory protein.

    Xianqiang Li;P. Coffino

  • The cytoplasmic Hsp70 chaperone machinery subjects misfolded and endoplasmic reticulum import-incompetent proteins to degradation via the ubiquitin-proteasome system.

    Sae-Hun Park;Natalia Bolender;Frederik Eisele;Zlatka Kostova

  • Cyclic AMP-dependent protein kinase: pivotal role in regulation of enzyme induction and growth.

    Paul A. Insel;Henry R. Bourne;Philip Coffino;Gordon M. Tomkins

  • Regulated degradation of ornithine decarboxylase requires interaction with the polyamine-inducible protein antizyme

    X Li;P Coffino

  • Structure of mammalian ornithine decarboxylase at 1.6 Å resolution: stereochemical implications of PLP-dependent amino acid decarboxylases

    Andrew D Kern;Marcos A Oliveira;Philip Coffino;Marvin L Hackert

  • Eighth International Workshop on Human Gene Mapping

    A.C. Chandley;P. Goetz;T.B. Hargreave;A.M. Joseph

Frequent Co-Authors

Henry R. Bourne
Henry R. Bourne University of California, San Francisco
Paul A. Insel
Paul A. Insel University of California, San Diego
Gordon M. Tomkins
Gordon M. Tomkins University of California, San Francisco
Ching C. Wang
Ching C. Wang University of California, San Francisco
Dieter H. Wolf
Dieter H. Wolf University of Stuttgart
Kathleen M. Sakamoto
Kathleen M. Sakamoto Stanford University
Olli A. Jänne
Olli A. Jänne University of Helsinki
Peter D'Eustachio
Peter D'Eustachio New York University
Kay Hofmann
Kay Hofmann University of Cologne
Joe W. Gray
Joe W. Gray Oregon Health & Science University

External Links

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Best Scientists Citing Philip Coffino

Anthony E. Pegg

Anthony E. Pegg

Pennsylvania State University

Publications: 40

Andreas T Matouschek

Andreas T Matouschek

The University of Texas at Austin

Publications: 29

John F. Atkins

John F. Atkins

University College Cork

Publications: 27

Paul A. Insel

Paul A. Insel

University of California, San Diego

Publications: 27

Buddy Ullman

Buddy Ullman

Oregon Health & Science University

Publications: 20

Ivaylo Ivanov

Ivaylo Ivanov

Georgia State University

Publications: 20

Andreas Martin

Andreas Martin

University of California, Berkeley

Publications: 20

Kazuei Igarashi

Kazuei Igarashi

Chiba University

Publications: 17

Raymond F. Gesteland

Raymond F. Gesteland

University of Utah

Publications: 17

Juhani Jänne

Juhani Jänne

University of Eastern Finland

Publications: 17

Ching C. Wang

Ching C. Wang

University of California, San Francisco

Publications: 16

Lawrence Banks

Lawrence Banks

International Centre for Genetic Engineering and Biotechnology

Publications: 15

Robert A. Casero

Robert A. Casero

Johns Hopkins University School of Medicine

Publications: 15

Laurence J. Marton

Laurence J. Marton

Renovorx

Publications: 15

Janet L. Stein

Janet L. Stein

University of Vermont

Publications: 14

Daniel Finley

Daniel Finley

Harvard University

Publications: 14

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