World's Best Scientists 2026 revealed!

D-Index & Metrics

Molecular Biology

D-Index
68
Citations
12071
World Ranking
1540
National Ranking
780

Overview

Buddy Ullman is affiliated with Oregon Health & Science University in the United States. Their research spans key areas within biochemistry, genetics, and molecular biology, as well as medicine.

The main fields of study associated with their work include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Within these fields, their research further focuses on subfields such as:

  • Molecular Biology
  • Oncology
  • Cancer Research

Ullman's scientific contributions concentrate on several topics, notably:

  • Ubiquitin and proteasome pathways
  • Peptidase Inhibition and Analysis
  • Signaling Pathways in Disease
  • Protease and Inhibitor Mechanisms

They have recently published multiple papers, primarily addressing proteasome regulation and inhibition mechanisms. Notable examples include:

  • Rapaprotin is Activated by an Endopeptidase to Disassemble 26S Proteasome, 2025, bioRxiv (Cold Spring Harbor Laboratory)
  • Rapaprotin, an Endopeptidase-Activated Proteasome Inhibitor that Induces 26S Disassembly, 2025, Angewandte Chemie
  • Rapaprotin, an Endopeptidase-Activated Proteasome Inhibitor that Induces 26S Disassembly, 2025, Angewandte Chemie International Edition

The venues frequently publishing Ullman's work include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Angewandte Chemie
  • Angewandte Chemie International Edition

Collaboration is a notable aspect of their career. Ullman has worked repeatedly with several coauthors, including:

  • Hanjing Peng
  • Zufeng Guo
  • Wei Li Wang
  • Deyao Yin
  • Shitao Zou

Best Publications

  • Insertional tagging, cloning, and expression of the Toxoplasma gondii hypoxanthine-xanthine-guanine phosphoribosyltransferase gene. Use as a selectable marker for stable transformation.

    Robert G.K. Donald;Darrick Carter;Buddy Ullman;David S. Roos

  • Deoxycytidine kinase-mediated toxicity of deoxyadenosine analogs toward malignant human lymphoblasts in vitro and toward murine L1210 leukemia in vivo

    Dennis A. Carson;Donald B. Wasson;Jonathan Kaye;Buddy Ullman

  • Deoxyadenosine metabolism and cytotoxicity in cultured mouse T lymphoma cells: a model for immunodeficiency disease

    Buddy Ullman;Lorraine J. Gudas;Amos Cohen;David W. Martin

  • Mutator phenotypes in mammalian cell mutants with distinct biochemical defects and abnormal deoxyribonucleoside triphosphate pools.

    Guy Weinberg;Buddy Ullman;David W. Martin

  • Cytotoxicity of 5-fluoro-2'-deoxyuridine: requirement for reduced folate cofactors and antagonism by methotrexate

    Buddy Ullman;Melinda Lee;David W. Martin;Daniel V. Santi

  • Arginase Plays a Pivotal Role in Polyamine Precursor Metabolism in Leishmania CHARACTERIZATION OF GENE DELETION MUTANTS

    Sigrid C. Roberts;Michael J. Tancer;Michelle R. Polinsky;K. Michael Gibson

  • High efficiency plating method for Leishmania promastigotes in semidefined or completely-defined medium.

    David M. Iovannisci;Buddy Ullman

  • Isolation and characterization of purine-nucleoside phosphorylase-deficient T-lymphoma cells and secondary mutants with altered ribonucleotide reductase: Genetic model for immunodeficiency disease

    Buddy Ullman;Lorraine J. Gudas;Shirley M. Clift;David W. Martin

  • Characterization of a cell culture model for the study of adenosine deaminase- and purine nucleoside phosphorylase-deficient immunologic disease

    B. Ullman;A. Cohen;D.W. Martin

  • Multidrug resistance in Leishmania donovani is conferred by amplification of a gene homologous to the mammalian mdr1 gene.

    D M Henderson;C D Sifri;M Rodgers;D F Wirth

  • Deoxyguanosine toxicity in a mouse T lymphoma: Relationship to purine nucleoside phosphorylase-associated immune dysfunction

    Lorraine J. Gudas;Buddy Ullman;Amos Cohen;David W. Martin

  • Characterization of a mutant mouse lymphoma cell with deficient transport of purine and pyrimidine nucleosides.

    A Cohen;B Ullman;D W Martin

  • Effects of mutational loss of adenosine kinase and deoxycytidine kinase on deoxyATP accumulation and deoxyadenosine toxicity in cultured CEM human T-lymphoblastoid cells

    M S Hershfield;J E Fetter;W C Small;A S Bagnara

  • Two high affinity nucleoside transporters in Leishmania donovani.

    Bruce Aronow;Kiran J Kaur;Kathleen McCartan;Buddy Ullman

  • Isolation and functional characterization of the PfNT1 nucleoside transporter gene from Plasmodium falciparum.

    Nicola S. Carter;Choukri Ben Mamoun;Wei Liu;Edilene O. Silva;Edilene O. Silva

  • Crystal structures of Toxoplasma gondii adenosine kinase reveal a novel catalytic mechanism and prodrug binding.

    Maria A Schumacher;Daniel M Scott;Iripam I Mathews;Steven E Ealick

  • Nucleoside and Nucleobase Transporters in Parasitic Protozoa

    Scott M. Landfear;Buddy Ullman;Nicola S. Carter;Marco A. Sanchez

  • Cloning of Leishmania nucleoside transporter genes by rescue of a transport-deficient mutant.

    Gayatri Vasudevan;Nicola S. Carter;Mark E. Drew;Mark E. Drew;Stephen M. Beverley

  • Purine salvage pathways in the Apicomplexan parasite Toxoplasma gondii

    Kshitiz Chaudhary;John A. Darling;Leah M. Fohl;William J. Sullivan

  • Identification and characterization of a polyamine permease from the protozoan parasite Leishmania major

    Marie Pierre Hasne;Buddy Ullman

Frequent Co-Authors

David W. Martin
David W. Martin University of Toronto
Lorraine J. Gudas
Lorraine J. Gudas Cornell University
David S. Roos
David S. Roos University of Pennsylvania
Richard G. Brennan
Richard G. Brennan Duke University
Mary E. Wilson
Mary E. Wilson University of California, San Francisco
Maria A. Schumacher
Maria A. Schumacher Duke University
David W. Christianson
David W. Christianson University of Pennsylvania
Bruce J. Aronow
Bruce J. Aronow Cincinnati Children's Hospital Medical Center
Choukri Ben Mamoun
Choukri Ben Mamoun Yale University
Dyann F. Wirth
Dyann F. Wirth Harvard University

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