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Lorraine J. Gudas

Lorraine J. Gudas

D-Index & Metrics

Biology and Biochemistry

D-Index
88
Citations
25895
World Ranking
2719
National Ranking
1410

Research.com Recognitions

  • 2008 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Lorraine J. Gudas is affiliated with Cornell University in the United States. Their research primarily spans the fields of biochemistry, genetics, and molecular biology, with significant contributions also in medicine. Key subfields include molecular biology, epidemiology, pathology and forensic medicine, cancer research, and genetics.

The main topics of their work include:

  • Retinoids in leukemia and cellular processes
  • Liver disease diagnosis and treatment
  • Alcohol consumption and health effects
  • Renal and related cancers
  • Cancer-related molecular mechanisms research
  • Cancer-related gene regulation
  • Epigenetics and DNA methylation

They have published extensively in several journals, with frequent appearances in the Journal of Biological Chemistry, The FASEB Journal, Neoplasia, Journal of Molecular Endocrinology, and Frontiers in Pharmacology.

Recent papers authored by Lorraine J. Gudas include:

  • "Retinoid metabolism: new insights" (2022) in Journal of Molecular Endocrinology
  • "Synthetic Retinoids Beyond Cancer Therapy" (2021) in The Annual Review of Pharmacology and Toxicology

Frequent co-authors collaborating with Lorraine J. Gudas include Xiao-Han Tang, Marta Melis, Tuo Zhang, Kristian B. Laursen, and Steven E. Trasino.

In recognition of their contributions to science, Lorraine J. Gudas was named a Fellow of the American Association for the Advancement of Science (AAAS) in 2008.

Best Publications

  • Cellular Biology and Biochemistry of the Retinoids

    Anita B. Roberts;Michael B. Sporn

  • Retinoids, Retinoic Acid Receptors, and Cancer

    Xiao-Han Tang;Lorraine J. Gudas

  • Differential expression of genes encoding alpha, beta and gamma retinoic acid receptors and CRABP in the developing limbs of the mouse.

    Pascal Dollé;Esther Ruberte;Philippe Kastner;Martin Petkovich

  • Regulation of Stem Cell Pluripotency and Differentiation Involves a Mutual Regulatory Circuit of the Nanog, OCT4, and SOX2 Pluripotency Transcription Factors With Polycomb Repressive Complexes and Stem Cell microRNAs

    Vasundhra Kashyap;Naira C. Rezende;Kymora B. Scotland;Sebastian M. Shaffer

  • RETINOIDS REGULATE STEM CELL DIFFERENTIATION

    Lorraine J. Gudas;John A. Wagner

  • Overexpression of the cellular retinoic acid binding protein-I (CRABP-I) results in a reduction in differentiation-specific gene expression in F9 teratocarcinoma cells.

    J F Boylan;L J Gudas

  • Retinoids and vertebrate development.

    L J Gudas

  • Oral Cavity and Esophageal Carcinogenesis Modeled in Carcinogen-Treated Mice

    Xiao-Han Tang;Beatrice Knudsen;Debra Bemis;Satish Tickoo

  • A retinoic acid-responsive element is present in the 5' flanking region of the laminin B1 gene

    George W. Vasios;Joseph D. Gold;Martin Petkovich;Pierre Chambon

  • The Roles of Retinoids in Vertebrate Development

    Anna L. Means;Lorraine J. Gudas

  • Rex-1, a Gene Encoding a Transcription Factor Expressed in the Early Embryo, Is Regulated via Oct-3/4 and Oct-6 Binding to an Octamer Site and a Novel Protein, Rox-1, Binding to an Adjacent Site

    Etti Ben-Shushan;James R. Thompson;Lorraine J. Gudas;Yehudit Bergman

  • Identification of a retinoic acid responsive enhancer 3′ of the murine homeobox gene Hox-1.6

    Alexander W. Langston;Lorraine J. Gudas

  • Specific expression of a retinoic acid-regulated, zinc-finger gene, Rex-1, in preimplantation embryos, trophoblast and spermatocytes.

    M.B. Rogers;B.A. Hosler;L.J. Gudas

  • The level of CRABP-I expression influences the amounts and types of all-trans-retinoic acid metabolites in F9 teratocarcinoma stem cells.

    J F Boylan;L J Gudas

  • DNA synthesis inhibition and the induction of protein X in Escherichia coli.

    Lorraine J. Gudas;Arthur B. Pardee

  • Deoxyadenosine metabolism and cytotoxicity in cultured mouse T lymphoma cells: a model for immunodeficiency disease

    Buddy Ullman;Lorraine J. Gudas;Amos Cohen;David W. Martin

  • Abnormal Expression of Retinoic Acid Receptors and Keratin 19 by Human Oral and Epidermal Squamous Cell Carcinoma Cell Lines

    Lan Hu;David L. Crowe;James G. Rheinwald;Pierre Chambon

  • Model for regulation of Escherichia coli DNA repair functions

    Lorraine J. Gudas;Arthur B. Pardee

  • Deoxyguanosine Triphosphate as a Possible Toxic Metabolite in the Immunodeficiency Associated with Purine Nucleoside Phosphorylase Deficiency

    Amos Cohen;Lorraine J. Gudas;Arthur J. Ammann;Gerard E. J. Staal

  • Early retinoic acid-induced F9 teratocarcinoma stem cell gene ERA-1: alternate splicing creates transcripts for a homeobox-containing protein and one lacking the homeobox.

    G J LaRosa;L J Gudas

Frequent Co-Authors

David M. Nanus
David M. Nanus Cornell University
David W. Martin
David W. Martin University of Toronto
Buddy Ullman
Buddy Ullman Oregon Health & Science University
Douglas S. Scherr
Douglas S. Scherr Cornell University
Pierre Chambon
Pierre Chambon Institute of Genetics and Molecular and Cellular Biology
Robert R. Rando
Robert R. Rando University of Padua
Dean Bok
Dean Bok University of California, Los Angeles
Jay D. Raman
Jay D. Raman Penn State Milton S. Hershey Medical Center
Steven S. Gross
Steven S. Gross Cornell University

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