D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 85 Citations 21,688 319 World Ranking 2051 National Ranking 1144

Research.com Recognitions

Awards & Achievements

2008 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • Enzyme
  • DNA

Lorraine J. Gudas mainly focuses on Retinoic acid, Molecular biology, Cellular differentiation, Biochemistry and Cell biology. Her Retinoic acid study which covers Gene expression that intersects with Pathology. Her Molecular biology research integrates issues from Homeobox, cDNA library, Messenger RNA and Mutant.

Her Cellular differentiation study incorporates themes from Homeobox protein Nkx-2.5, EMX2, CDX2, Retinol and Regulation of gene expression. Within one scientific family, Lorraine J. Gudas focuses on topics pertaining to Embryonic stem cell under Cell biology, and may sometimes address concerns connected to Blastocyst, Spermatogenesis and Germ cell. Her work carried out in the field of Retinoid brings together such families of science as Cell signaling, Signal transduction, Cancer research, Transcription factor and Receptor.

Her most cited work include:

  • Differential expression of genes encoding α, β and γ retinoic acid receptors and CRABP in the developing limbs of the mouse (402 citations)
  • Retinoids, Retinoic Acid Receptors, and Cancer (370 citations)
  • Regulation of Stem Cell Pluripotency and Differentiation Involves a Mutual Regulatory Circuit of the Nanog, OCT4, and SOX2 Pluripotency Transcription Factors With Polycomb Repressive Complexes and Stem Cell microRNAs (329 citations)

What are the main themes of her work throughout her whole career to date?

The scientist’s investigation covers issues in Molecular biology, Retinoic acid, Cellular differentiation, Cancer research and Biochemistry. She has included themes like Cell culture, Gene expression, Wild type, Mutant and Stem cell in her Molecular biology study. Her research integrates issues of Regulation of gene expression and Cell biology in her study of Retinoic acid.

Her studies in Cellular differentiation integrate themes in fields like Acute promyelocytic leukemia, Embryonic stem cell and Receptor. Her work in Cancer research addresses subjects such as Pathology, which are connected to disciplines such as Kidney. Her work carried out in the field of Retinoid brings together such families of science as Endocrinology, Internal medicine and Retinol.

She most often published in these fields:

  • Molecular biology (44.30%)
  • Retinoic acid (42.72%)
  • Cellular differentiation (21.84%)

What were the highlights of her more recent work (between 2011-2021)?

  • Cancer research (20.89%)
  • Retinoic acid (42.72%)
  • Internal medicine (15.51%)

In recent papers she was focusing on the following fields of study:

Her scientific interests lie mostly in Cancer research, Retinoic acid, Internal medicine, Cellular differentiation and Cell biology. Her Cancer research research incorporates themes from Cell, Retinoid, Carcinogenesis, Cancer and Transcription factor. Lorraine J. Gudas does research in Retinoic acid, focusing on Retinoic acid receptor specifically.

Her Internal medicine study integrates concerns from other disciplines, such as Endocrinology and Oncology. Her Cellular differentiation study combines topics in areas such as Acute promyelocytic leukemia, Differentiation therapy, Molecular biology and Myeloid leukemia. The various areas that Lorraine J. Gudas examines in her Cell biology study include Embryonic stem cell, Epigenetic regulation of neurogenesis, Biochemistry and Genetics.

Between 2011 and 2021, her most popular works were:

  • Emerging roles for retinoids in regeneration and differentiation in normal and disease states. (109 citations)
  • Expression of VEGF and its receptors VEGFR1/VEGFR2 is Associated with Invasiveness of Bladder Cancer (79 citations)
  • The lysine specific demethylase-1 (LSD1/KDM1A) regulates VEGF-A expression in prostate cancer. (62 citations)

In her most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • DNA

Her primary areas of investigation include Cancer research, Cellular differentiation, Retinoic acid, Molecular biology and Cell biology. Her research integrates issues of EZH2, Histone methyltransferase activity, Prostate cancer, LNCaP and 4-Nitroquinoline 1-oxide in her study of Cancer research. Her research in Cellular differentiation intersects with topics in Acute promyelocytic leukemia, Transcription factor, Wnt signaling pathway and Autophagy.

Lorraine J. Gudas specializes in Retinoic acid, namely Retinoic acid receptor. Lorraine J. Gudas has researched Molecular biology in several fields, including Histone and DNA methylation. Lorraine J. Gudas interconnects Spleen, Embryonic stem cell, Epigenetic regulation of neurogenesis and Genetics in the investigation of issues within Cell biology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Differential expression of genes encoding alpha, beta and gamma retinoic acid receptors and CRABP in the developing limbs of the mouse.

Pascal Dollé;Esther Ruberte;Philippe Kastner;Martin Petkovich.
Nature (1989)

646 Citations

Retinoids, Retinoic Acid Receptors, and Cancer

Xiao-Han Tang;Lorraine J. Gudas.
Annual Review of Pathology-mechanisms of Disease (2011)

566 Citations

Regulation of Stem Cell Pluripotency and Differentiation Involves a Mutual Regulatory Circuit of the Nanog, OCT4, and SOX2 Pluripotency Transcription Factors With Polycomb Repressive Complexes and Stem Cell microRNAs

Vasundhra Kashyap;Naira C. Rezende;Kymora B. Scotland;Sebastian M. Shaffer.
Stem Cells and Development (2009)

502 Citations

Overexpression of the cellular retinoic acid binding protein-I (CRABP-I) results in a reduction in differentiation-specific gene expression in F9 teratocarcinoma cells.

J F Boylan;L J Gudas.
Journal of Cell Biology (1991)

448 Citations

Retinoids and vertebrate development.

L J Gudas.
Journal of Biological Chemistry (1994)

435 Citations

RETINOIDS REGULATE STEM CELL DIFFERENTIATION

Lorraine J. Gudas;John A. Wagner.
Journal of Cellular Physiology (2011)

434 Citations

Rex-1, a Gene Encoding a Transcription Factor Expressed in the Early Embryo, Is Regulated via Oct-3/4 and Oct-6 Binding to an Octamer Site and a Novel Protein, Rox-1, Binding to an Adjacent Site

Etti Ben-Shushan;James R. Thompson;Lorraine J. Gudas;Yehudit Bergman.
Molecular and Cellular Biology (1998)

396 Citations

The Roles of Retinoids in Vertebrate Development

Anna L. Means;Lorraine J. Gudas.
Annual Review of Biochemistry (1995)

392 Citations

A retinoic acid-responsive element is present in the 5' flanking region of the laminin B1 gene

George W. Vasios;Joseph D. Gold;Martin Petkovich;Pierre Chambon.
Proceedings of the National Academy of Sciences of the United States of America (1989)

373 Citations

Identification of a retinoic acid responsive enhancer 3′ of the murine homeobox gene Hox-1.6

Alexander W. Langston;Lorraine J. Gudas.
Mechanisms of Development (1992)

359 Citations

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