What is he best known for?
The fields of study he is best known for:
His scientific interests lie mostly in Retinoic acid, Cell biology, Molecular biology, Nuclear receptor and Retinoid X receptor.
His Retinoic acid research integrates issues from Receptor and Endocrinology.
He works mostly in the field of Endocrinology, limiting it down to topics relating to Homeotic gene and, in certain cases, Internal medicine, as a part of the same area of interest.
His Cell biology study incorporates themes from Genetics, Gene expression profiling, Cellular differentiation and Human genetics.
Philippe Kastner interconnects Promoter and Gene isoform in the investigation of issues within Molecular biology.
Philippe Kastner has researched Retinoid X receptor in several fields, including Retinoid X receptor gamma and Retinoic acid receptor alpha.
His most cited work include:
- The nuclear receptor superfamily: the second decade. (6118 citations)
- Two distinct estrogen‐regulated promoters generate transcripts encoding the two functionally different human progesterone receptor forms A and B. (1312 citations)
- Purification, cloning, and RXR identity of the HeLa cell factor with which RAR or TR heterodimerizes to bind target sequences efficiently (1003 citations)
What are the main themes of his work throughout his whole career to date?
Philippe Kastner focuses on Cell biology, Molecular biology, Retinoic acid, Immunology and Retinoid X receptor.
His Cell biology research incorporates themes from Genetics, Ikaros Transcription Factor and Cellular differentiation.
His Molecular biology research incorporates elements of Gene expression, Complementary DNA, Gene, Exon and Gene isoform.
His work deals with themes such as Receptor and Human skin, which intersect with Retinoic acid.
In Receptor, Philippe Kastner works on issues like Retinoid, which are connected to Mutant.
His Retinoid X receptor study is concerned with the field of Biochemistry as a whole.
He most often published in these fields:
- Cell biology (52.80%)
- Molecular biology (40.80%)
- Retinoic acid (35.20%)
What were the highlights of his more recent work (between 2013-2021)?
- Cell biology (52.80%)
- Ikaros Transcription Factor (18.40%)
- B cell (10.40%)
In recent papers he was focusing on the following fields of study:
His primary areas of study are Cell biology, Ikaros Transcription Factor, B cell, Transcription factor and Immunology.
His work on STAT5 as part of general Cell biology research is frequently linked to Zinc Finger Protein Helios, bridging the gap between disciplines.
His Ikaros Transcription Factor study combines topics from a wide range of disciplines, such as Cell, Protein kinase B, B-cell receptor and Cellular differentiation.
The concepts of his B cell study are interwoven with issues in Haploinsufficiency, Lymphoblastic leukaemia, MAPK/ERK pathway and Cancer research.
His Transcription factor study integrates concerns from other disciplines, such as Molecular biology and Effector.
His work blends Molecular biology and Lysine studies together.
Between 2013 and 2021, his most popular works were:
- Stable inhibitory activity of regulatory T cells requires the transcription factor Helios (189 citations)
- Fold change rank ordering statistics: a new method for detecting differentially expressed genes (79 citations)
- The Tumor Suppressor Ikaros Shapes the Repertoire of Notch Target Genes in T Cells (53 citations)
In his most recent research, the most cited papers focused on:
Cell biology, Regulation of gene expression, Transcription factor, Ikaros Transcription Factor and Immunology are his primary areas of study.
In most of his Cell biology studies, his work intersects topics such as FOXP3.
His Regulation of gene expression research includes elements of Chromatin, T cell, Cell type and Notch signaling pathway.
His studies in Transcription factor integrate themes in fields like Molecular biology, Cellular differentiation, Transgene and Ectopic expression.
His work deals with themes such as Cyclin-dependent kinase 8, Gene silencing and Notch proteins, which intersect with Ikaros Transcription Factor.
Philippe Kastner regularly ties together related areas like STAT5 in his Immunology studies.
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