World's Best Scientists 2026 revealed!
Koichi Akashi

Koichi Akashi

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Biology and Biochemistry
Japan
2026
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Medicine
Japan
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
109
Citations
52994
World Ranking
991
National Ranking
50

Medicine

D-Index
109
Citations
53370
World Ranking
5703
National Ranking
127

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in Japan Leader Award
  • 2025 - Research.com Biology and Biochemistry in Japan Leader Award
  • 2023 - Research.com Biology and Biochemistry in Japan Leader Award
  • 2023 - Research.com Medicine in Japan Leader Award

Overview

Koichi Akashi is affiliated with Kyushu University in Japan and has contributed extensively to the field of medicine, with a research focus encompassing hematology, oncology, immunology, molecular biology, and genetics.

The scientist's work is associated with several main topics including:

  • Acute Myeloid Leukemia Research
  • Lymphoma Diagnosis and Treatment
  • CAR-T cell therapy research
  • Hematopoietic Stem Cell Transplantation
  • Chronic Myeloid Leukemia Treatments
  • SARS-CoV-2 and COVID-19 Research
  • T-cell and B-cell Immunology

Frequent publication venues where Koichi Akashi has contributed include:

  • Blood
  • International Journal of Hematology
  • Cancer Science
  • Leukemia
  • Research Square (Research Square)

Notable coauthors in collaboration with Akashi are:

  • Toshihiro Miyamoto
  • Koji Kato
  • Hiroaki Niiro
  • Eishi Baba
  • Takahiko Horiuchi

Recent papers by Koichi Akashi include:

  • RNA N6-methyladenosine demethylase FTO regulates PD-L1 expression in colon cancer cells, 2020, Biochemical and Biophysical Research Communications
  • OX40 and LAG3 are associated with better prognosis in advanced gastric cancer patients treated with anti-programmed death-1 antibody, 2020, British Journal of Cancer
  • Helper T cell-dominant tertiary lymphoid structures are associated with disease relapse of advanced colorectal cancer, 2020, OncoImmunology
  • Bone marrow-derived macrophages converted into cancer-associated fibroblast-like cells promote pancreatic cancer progression, 2021, Cancer Letters
  • Generation of functional oocytes from male mice in vitro, 2023, Nature

Best Publications

  • A clonogenic common myeloid progenitor that gives rise to all myeloid lineages

    Koichi Akashi;Koichi Akashi;David Traver;Toshihiro Miyamoto;Irving L. Weissman

  • Identification of Clonogenic Common Lymphoid Progenitors in Mouse Bone Marrow

    Motonari Kondo;Irving L. Weissman;Koichi Akashi

  • The aging of hematopoietic stem cells

    Sean J. Morrison;Antoni M. Wandycz;Koichi Akashi;Amiela Globerson

  • Chemotherapy-resistant human AML stem cells home to and engraft within the bone-marrow endosteal region.

    Fumihiko Ishikawa;Shuro Yoshida;Yoriko Saito;Atsushi Hijikata

  • Development of functional human blood and immune systems in NOD/SCID/IL2 receptor γ chainnull mice

    Fumihiko Ishikawa;Masaki Yasukawa;Bonnie Lyons;Shuro Yoshida

  • Bcl-2 Rescues T Lymphopoiesis in Interleukin-7 Receptor–Deficient Mice

    Koichi Akashi;Motonari Kondo;Ursula von Freeden-Jeffry;Richard Murray

  • MOZ-TIF2, but not BCR-ABL, confers properties of leukemic stem cells to committed murine hematopoietic progenitors

    Brian J.P. Huntly;Hirokazu Shigematsu;Kenji Deguchi;Benjamin H. Lee

  • Mouse development and cell proliferation in the absence of D-cyclins.

    Katarzyna Kozar;Maria A. Ciemerych;Vivienne I. Rebel;Hirokazu Shigematsu

  • Prospective isolation of human clonogenic common myeloid progenitors

    Markus G. Manz;Toshihiro Miyamoto;Koichi Akashi;Irving L. Weissman

  • Obligate role of anti-apoptotic MCL-1 in the survival of hematopoietic stem cells.

    Joseph T. Opferman;Hiromi Iwasaki;Christy C. Ong;Christy C. Ong;Heikyung Suh;Heikyung Suh

  • AML1/ETO-expressing nonleukemic stem cells in acute myelogenous leukemia with 8;21 chromosomal translocation

    Toshihiro Miyamoto;Irving L. Weissman;Koichi Akashi;Koichi Akashi

  • Enhancement of Hematopoietic Stem Cell Repopulating Capacity and Self-Renewal in the Absence of the Transcription Factor C/EBPα

    Pu Zhang;Junko Iwasaki-Arai;Hiromi Iwasaki;Maris L. Fenyus

  • Acute myeloid leukemia induced by graded reduction of a lineage-specific transcription factor, PU.1.

    Frank Rosenbauer;Katharina Wagner;Jeffery L Kutok;Hiromi Iwasaki

  • Expression of DNA methyltransferases DNMT1, 3A, and 3B in normal hematopoiesis and in acute and chronic myelogenous leukemia.

    Shin Ichi Mizuno;Takahito Chijiwa;Takashi Okamura;Koichi Akashi

  • Dendritic cell potentials of early lymphoid and myeloid progenitors.

    Markus G. Manz;David Traver;David Traver;Toshihiro Miyamoto;Toshihiro Miyamoto;Irving L. Weissman;Irving L. Weissman

  • Development of CD8α-Positive Dendritic Cells from a Common Myeloid Progenitor

    David Traver;Koichi Akashi;Markus Manz;Miriam Merad

  • Cell-fate conversion of lymphoid-committed progenitors by instructive actions of cytokines

    Motonari Kondo;David C. Scherer;Toshihiro Miyamoto;Angela G. King

  • Myeloid or Lymphoid Promiscuity as a Critical Step in Hematopoietic Lineage Commitment

    Toshihiro Miyamoto;Hiromi Iwasaki;Boris Reizis;Min Ye

  • Distinctive and indispensable roles of PU.1 in maintenance of hematopoietic stem cells and their differentiation.

    Hiromi Iwasaki;Chamorro Somoza;Hirokazu Shigematsu;Estelle A. Duprez

  • MOZ-TIF2, but Not BCR-ABL, Confers Properties of Leukemic Stem Cells to Committed Murine Hematopoietic Progenitors.

    Brian J.P. Huntly;Hirokazu Shigematzu;Kenji Deguchi;Benjamin Lee

Frequent Co-Authors

Toshihiro Miyamoto
Toshihiro Miyamoto Kyushu University
Takanori Teshima
Takanori Teshima Hokkaido University
Mine Harada
Mine Harada Kyushu University
Hiroaki Niiro
Hiroaki Niiro Kyushu University
Yoshiyuki Niho
Yoshiyuki Niho Kyushu University
Irving L. Weissman
Irving L. Weissman Stanford University
Daniel G. Tenen
Daniel G. Tenen National University of Singapore
Kazuya Shimoda
Kazuya Shimoda University of Miyazaki
Shinji Shimoda
Shinji Shimoda Kyushu University
Koichi Ohshima
Koichi Ohshima Kurume University

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