His primary areas of study are Immunology, Primary biliary cirrhosis, Molecular biology, T cell and Epitope. His Immunology study frequently draws connections to other fields, such as Cytotoxic T cell. The various areas that Shinji Shimoda examines in his Primary biliary cirrhosis study include Biliary tract, Antigen, Pathology, Chemokine and Peripheral blood mononuclear cell.
His studies deal with areas such as Autoantibody and Cell division as well as Peripheral blood mononuclear cell. His Molecular biology research is multidisciplinary, relying on both Progenitor cell, In situ hybridization and Cord blood. The Epitope study combines topics in areas such as Molecular mimicry and Biochemistry, Peptide.
Shinji Shimoda mainly focuses on Internal medicine, Immunology, Gastroenterology, Primary biliary cirrhosis and Ribavirin. Shinji Shimoda combines subjects such as Chronic hepatitis, Telaprevir and Hepatitis C virus with his study of Internal medicine. His Immunology study frequently draws connections to adjacent fields such as Cytotoxic T cell.
His research investigates the link between Gastroenterology and topics such as Hepatocellular carcinoma that cross with problems in Incidence and Hazard ratio. His research in Primary biliary cirrhosis intersects with topics in Biliary tract, Pathology, Peripheral blood mononuclear cell and Epitope, Antibody. The study incorporates disciplines such as Molecular biology and Peptide in addition to T cell.
Shinji Shimoda focuses on Internal medicine, Gastroenterology, Cirrhosis, Sofosbuvir and Immunology. The Internal medicine study which covers Oncology that intersects with Chemotherapy. The Gastroenterology study combines topics in areas such as Genotype and Hepatitis C virus.
Shinji Shimoda studied Cirrhosis and Pathology that intersect with Molecular biology. His Clinical significance research extends to the thematically linked field of Immunology. His work often combines Primary biliary cirrhosis and In patient studies.
Internal medicine, Cirrhosis, Gastroenterology, Immunology and Adverse effect are his primary areas of study. His study in the fields of Odds ratio under the domain of Internal medicine overlaps with other disciplines such as Coagulase. Shinji Shimoda has researched Cirrhosis in several fields, including Cholestasis, Ursodeoxycholic acid, Secretion and Disease, Pathology.
He interconnects Bile duct, Hepatology and Primary biliary cirrhosis in the investigation of issues within Cholestasis. The concepts of his Gastroenterology study are interwoven with issues in Cohort study, Cohort and Hepatitis C virus. Shinji Shimoda regularly links together related areas like Hematopoietic stem cell transplantation in his Immunology studies.
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HLA DRB4 0101-restricted immunodominant T cell autoepitope of pyruvate dehydrogenase complex in primary biliary cirrhosis: evidence of molecular mimicry in human autoimmune diseases.
Shinji Shimoda;Minoru Nakamura;Hiromi Ishibashi;Kazuhiro Hayashida.
Journal of Experimental Medicine (1995)
Liver‐targeted and peripheral blood alterations of regulatory T cells in primary biliary cirrhosis
Ruth Y. Lan;Chunmei Cheng;Zhe Xiong Lian;Koichi Tsuneyama.
Hepatology (2006)
Graft-versus-host disease disrupts intestinal microbial ecology by inhibiting Paneth cell production of α-defensins.
Yoshihiro Eriguchi;Shuichiro Takashima;Hideyo Oka;Sonoko Shimoji.
Blood (2012)
Identification and precursor frequency analysis of a common T cell epitope motif in mitochondrial autoantigens in primary biliary cirrhosis.
Shinji Shimoda;Shinji Shimoda;Judith A Van de Water;Aftab Ansari;Minoru Nakamura.
Journal of Clinical Investigation (1998)
Genome-wide association study identifies TNFSF15 and POU2AF1 as susceptibility loci for primary biliary cirrhosis in the Japanese population.
Minoru Nakamura;Nao Nishida;Minae Kawashima;Yoshihiro Aiba.
American Journal of Human Genetics (2012)
Altered monocyte responses to defined TLR ligands in patients with primary biliary cirrhosis
Tin K Mao;Zhe-Xiong Lian;Carlo Selmi;Carlo Selmi;Yasunori Ichiki.
Hepatology (2005)
Periductal interleukin‐17 production in association with biliary innate immunity contributes to the pathogenesis of cholangiopathy in primary biliary cirrhosis
K. Harada;Shinji Shimoda;Y. Sato;K. Isse.
Clinical and Experimental Immunology (2009)
Fractalkine and CX3CR1 are involved in the recruitment of intraepithelial lymphocytes of intrahepatic bile ducts
Kumiko Isse;Kenichi Harada;Yoh Zen;Takashi Kamihira.
Hepatology (2005)
Human intrahepatic biliary epithelial cells function in innate immunity by producing IL-6 and IL-8 via the TLR4-NF-kappaB and -MAPK signaling pathways.
Terufumi Yokoyama;Atsumasa Komori;Minoru Nakamura;Yasushi Takii.
Liver International (2006)
Mimicry peptides of human PDC-E2 163-176 peptide, the immunodominant T-cell epitope of primary biliary cirrhosis
Shinji Shimoda;Minoru Nakamura;Hirohisa Shigematsu;Hironori Tanimoto.
Hepatology (2000)
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