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Shinji Shimoda

Shinji Shimoda

D-Index & Metrics

Immunology

D-Index
59
Citations
9976
World Ranking
3453
National Ranking
139

Overview

Shinji Shimoda is affiliated with Kyushu University in Japan and has a research focus primarily within the field of Medicine. Their work spans several subfields including Hepatology, Epidemiology, Oncology, Surgery, and Orthodontics.

The scientist's research covers a range of topics, notably:

  • Liver Disease Diagnosis and Treatment
  • Hepatitis C virus research
  • Liver Diseases and Immunity
  • Hepatitis B Virus Studies
  • Pediatric Hepatobiliary Diseases and Treatments
  • Dental Erosion and Treatment
  • Dental materials and restorations

Recent significant publications by Shinji Shimoda include:

  • "Tenofovir alafenamide after switching from entecavir or nucleos(t)ide combination therapy for patients with chronic hepatitis B" (2020) published in Liver International
  • "Switching to tenofovir alafenamide for nucleos(t)ide analogue-experienced patients with chronic hepatitis B: week 144 results from a real-world, multi-centre cohort study" (2022) published in Alimentary Pharmacology & Therapeutics
  • "Safety, tolerability, and anti-fibrotic efficacy of the CBP/β-catenin inhibitor PRI-724 in patients with hepatitis C and B virus-induced liver cirrhosis: An investigator-initiated, open-label, non-randomised, multicentre, phase 1/2a study" (2022) published in EBioMedicine
  • "Integrated GWAS and mRNA Microarray Analysis Identified IFNG and CD40L as the Central Upstream Regulators in Primary Biliary Cholangitis" (2020) published in Hepatology Communications
  • "Ursodeoxycholic acid impairs liver-infiltrating T-cell chemotaxis through IFN-γ and CX3CL1 production in primary biliary cholangitis" (2021) published in European Journal of Immunology

The scientist has frequently published in journals such as:

  • Journal of Hepatology
  • Kanzo
  • Influenza and Other Respiratory Viruses
  • Journal of Gastroenterology and Hepatology
  • Journal of Hard Tissue Biology

Frequent collaborators in their research include:

  • Kazufumi Dohmen
  • Eiichi Ogawa
  • Makoto Nakamuta
  • Norihiro Furusyo
  • Toshimasa Koyanagi

Best Publications

  • HLA DRB4 0101-restricted immunodominant T cell autoepitope of pyruvate dehydrogenase complex in primary biliary cirrhosis: evidence of molecular mimicry in human autoimmune diseases.

    Shinji Shimoda;Minoru Nakamura;Hiromi Ishibashi;Kazuhiro Hayashida

  • Graft-versus-host disease disrupts intestinal microbial ecology by inhibiting Paneth cell production of α-defensins.

    Yoshihiro Eriguchi;Shuichiro Takashima;Hideyo Oka;Sonoko Shimoji

  • Liver‐targeted and peripheral blood alterations of regulatory T cells in primary biliary cirrhosis

    Ruth Y. Lan;Chunmei Cheng;Zhe Xiong Lian;Koichi Tsuneyama

  • Genome-wide association study identifies TNFSF15 and POU2AF1 as susceptibility loci for primary biliary cirrhosis in the Japanese population.

    Minoru Nakamura;Nao Nishida;Minae Kawashima;Yoshihiro Aiba

  • Identification and precursor frequency analysis of a common T cell epitope motif in mitochondrial autoantigens in primary biliary cirrhosis.

    Shinji Shimoda;Shinji Shimoda;Judith A Van de Water;Aftab Ansari;Minoru Nakamura

  • Periductal interleukin‐17 production in association with biliary innate immunity contributes to the pathogenesis of cholangiopathy in primary biliary cirrhosis

    K. Harada;Shinji Shimoda;Y. Sato;K. Isse

  • Liver architecture, cell function, and disease.

    Hiromi Ishibashi;Minoru Nakamura;Atsumasa Komori;Kiyoshi Migita

  • Altered monocyte responses to defined TLR ligands in patients with primary biliary cirrhosis

    Tin K Mao;Zhe-Xiong Lian;Carlo Selmi;Carlo Selmi;Yasunori Ichiki

  • Fractalkine and CX3CR1 are involved in the recruitment of intraepithelial lymphocytes of intrahepatic bile ducts

    Kumiko Isse;Kenichi Harada;Yoh Zen;Takashi Kamihira

  • Human intrahepatic biliary epithelial cells function in innate immunity by producing IL-6 and IL-8 via the TLR4-NF-kappaB and -MAPK signaling pathways.

    Terufumi Yokoyama;Atsumasa Komori;Minoru Nakamura;Yasushi Takii

  • Efficacy of pegylated interferon alpha-2b and ribavirin treatment on the risk of hepatocellular carcinoma in patients with chronic hepatitis C: A prospective, multicenter study

    Eiichi Ogawa;Norihiro Furusyo;Eiji Kajiwara;Kazuhiro Takahashi

  • Lymphocyte recruitment and homing to the liver in primary biliary cirrhosis and primary sclerosing cholangitis

    Andrea T. Borchers;Shinji Shimoda;Christopher Bowlus;Carl L. Keen

  • Interaction between Toll-like receptors and natural killer cells in the destruction of bile ducts in primary biliary cirrhosis

    Shinji Shimoda;Kenichi Harada;Hiroaki Niiro;Ken Shirabe

  • Antibody titer to gp210-C terminal peptide as a clinical parameter for monitoring primary biliary cirrhosis

    Minoru Nakamura;Yuki Shimizu-Yoshida;Yasushi Takii;Atsumasa Komori

  • Mimicry peptides of human PDC-E2 163-176 peptide, the immunodominant T-cell epitope of primary biliary cirrhosis

    Shinji Shimoda;Minoru Nakamura;Hirohisa Shigematsu;Hironori Tanimoto

  • Molecular mimicry of mitochondrial and nuclear autoantigens in primary biliary cirrhosis.

    Shinji Shimoda;Minoru Nakamura;Hiromi Ishibashi;Akira Kawano

  • CX3CL1 (fractalkine): A signpost for biliary inflammation in primary biliary cirrhosis

    Shinji Shimoda;Kenichi Harada;Hiroaki Niiro;Akinobu Taketomi

  • Short-term risk of hepatocellular carcinoma after hepatitis C virus eradication following direct-acting anti-viral treatment.

    E. Ogawa;N. Furusyo;H. Nomura;K. Dohmen

  • T cell immunity in autoimmune hepatitis.

    Yasunori Ichiki;Christopher A. Aoki;Christopher L. Bowlus;Shinji Shimoda

  • Safety, Tolerability, and Preliminary Efficacy of the Anti-Fibrotic Small Molecule PRI-724, a CBP/β-Catenin Inhibitor, in Patients with Hepatitis C Virus-related Cirrhosis: A Single-Center, Open-Label, Dose Escalation Phase 1 Trial

    Kiminori Kimura;Akemi Ikoma;Maki Shibakawa;Shinji Shimoda

  • Biliary epithelial cells and primary biliary cirrhosis: the role of liver-infiltrating mononuclear cells.

    Shinji Shimoda;Kenichi Harada;Hiroaki Niiro;Tomoharu Yoshizumi

Frequent Co-Authors

Hiromi Ishibashi
Hiromi Ishibashi Nagasaki University
Jun Hayashi
Jun Hayashi Haradoi Hospital
Minoru Nakamura
Minoru Nakamura Nagasaki University
Kazuhiro Takahashi
Kazuhiro Takahashi Tohoku University
M. Eric Gershwin
M. Eric Gershwin University of California, Davis
Koichi Akashi
Koichi Akashi Kyushu University
Yoshihiko Maehara
Yoshihiko Maehara Kyushu University
Yasuni Nakanuma
Yasuni Nakanuma Kanazawa University
Kiyoshi Migita
Kiyoshi Migita Fukushima Medical University
Mine Harada
Mine Harada Kyushu University

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