Immunology, Primary biliary cirrhosis, Autoimmunity, IL-2 receptor and CD8 are his primary areas of study. The Immunology study combines topics in areas such as Molecular biology and Cytotoxic T cell. Zhe-Xiong Lian combines subjects such as Hepatic fibrosis, Hepatic stellate cell, Natural killer T cell, Natural killer cell and Proinflammatory cytokine with his study of Primary biliary cirrhosis.
His Autoimmunity study combines topics in areas such as Myasthenia gravis, Molecular mimicry, Rheumatoid arthritis, Regulatory T cell and Multiple sclerosis. Zhe-Xiong Lian focuses mostly in the field of IL-2 receptor, narrowing it down to matters related to Interleukin 2 and, in some cases, Interleukin 17, Interleukin 10, Spleen and Immunopathology. In CD8, Zhe-Xiong Lian works on issues like T cell, which are connected to Autoimmune hepatitis, FOXP3, Hepatitis and CTL*.
Zhe-Xiong Lian focuses on Immunology, Primary biliary cirrhosis, Molecular biology, T cell and Autoimmunity. His work in Immunology is not limited to one particular discipline; it also encompasses Cytotoxic T cell. His biological study spans a wide range of topics, including Natural killer T cell, Autoantibody, Antibody and Endocrinology.
His work deals with themes such as In vitro, CD11c, MHC class I, Major histocompatibility complex and Epitope, which intersect with Molecular biology. His work in the fields of MHC class II overlaps with other areas such as Primary sclerosing cholangitis. His Autoimmunity research also works with subjects such as
His primary areas of investigation include Immunology, Primary biliary cirrhosis, Internal medicine, Receptor and Inflammation. His Immunology research is multidisciplinary, incorporating perspectives in Donor lymphocyte infusion, Subcutaneous injection and Transplantation. His Internal medicine research incorporates themes from Gastroenterology, Cytotoxic T cell and Endocrinology.
The concepts of his Endocrinology study are interwoven with issues in Autoantibody, Antibody, Rituximab, Immunophenotyping and Hepatology. His study in Receptor is interdisciplinary in nature, drawing from both Interleukin, Interleukin 17, Cytokine and Pathogenesis. He interconnects Cancer research, Colitis, Immunopathology, Transforming growth factor and Interleukin 12 in the investigation of issues within Inflammation.
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Identification of HLA-A2-restricted CD8(+) cytotoxic T cell responses in primary biliary cirrhosis: T cell activation is augmented by immune complexes cross-presented by dendritic cells.
Hiroto Kita;Zhe-Xiong Lian;Judy Van de Water;Xiao-Song He.
Journal of Experimental Medicine (2002)
Liver‐targeted and peripheral blood alterations of regulatory T cells in primary biliary cirrhosis
Ruth Y. Lan;Chunmei Cheng;Zhe Xiong Lian;Koichi Tsuneyama.
Quantitative and functional analysis of PDC-E2–specific autoreactive cytotoxic T lymphocytes in primary biliary cirrhosis
Hiroto Kita;Shuji Matsumura;Xiaosong He;Aftab A. Ansari.
Journal of Clinical Investigation (2002)
Regulatory T cells: development, function and role in autoimmunity.
Ruth Y. Lan;Aftab A. Ansari;Zhe Xiong Lian;M. Eric Gershwin.
Autoimmunity Reviews (2005)
Anti-Mitochondrial Antibodies and Primary Biliary Cirrhosis in TGF-β Receptor II Dominant-Negative Mice
Sabine Oertelt;Zhe Xiong Lian;Chun Mei Cheng;Ya Hui Chuang.
Journal of Immunology (2006)
Hepatic IL-17 responses in human and murine primary biliary cirrhosis.
Ruth Y Z Lan;Thucydides L. Salunga;Koichi Tsuneyama;Zhe Xiong Lian.
Journal of Autoimmunity (2009)
IL‐2 receptor α−/− mice and the development of primary biliary cirrhosis
Kanji Wakabayashi;Zhe-Xiong Lian;Yuki Moritoki;Ruth Y Lan.
Altered monocyte responses to defined TLR ligands in patients with primary biliary cirrhosis
Tin K Mao;Zhe-Xiong Lian;Carlo Selmi;Carlo Selmi;Yasunori Ichiki.
Heterogeneity of dendritic cells in the mouse liver: identification and characterization of four distinct populations.
Zhe Xiong Lian;Tomoyuki Okada;Xiaosong He;Hiroto Kita.
Journal of Immunology (2003)
Diverse Roles of Invariant Natural Killer T Cells in Liver Injury and Fibrosis Induced by Carbon Tetrachloride
Ogyi Park;Won Il Jeong;Lei Wang;Hua Wang.
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