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David Bryder

David Bryder

D-Index & Metrics

Biology and Biochemistry

D-Index
56
Citations
17579
World Ranking
14178
National Ranking
212

Overview

David Bryder is affiliated with Lund University in Sweden and has an extensive research portfolio primarily focused on hematology, immunology, and molecular biology. Their work spans medicine and biochemistry, genetics, and molecular biology, with over 49 publications in medicine, 37 in biochemistry, genetics, and molecular biology, and 30 in immunology and microbiology.

The scientist's research covers various subfields, notably hematology, immunology, and molecular biology. Additional areas include cancer research and genetics. Their investigative topics have addressed hematopoietic stem cell transplantation, acute myeloid leukemia research, and advanced techniques such as single-cell and spatial transcriptomics. Other key themes involve T-cell and B-cell immunology, immune cell function and interaction, epigenetics and DNA methylation, and immunotherapy and immune responses.

Their published papers include:

  • A self-sustaining layer of early-life-origin B cells drives steady-state IgA responses in the adult gut, 2022, Immunity
  • Temporal multimodal single-cell profiling of native hematopoiesis illuminates altered differentiation trajectories with age, 2023, Cell Reports
  • Continuous mitotic activity of primitive hematopoietic stem cells in adult mice, 2020, The Journal of Experimental Medicine
  • Reconciling Flux Experiments for Quantitative Modeling of Normal and Malignant Hematopoietic Stem/Progenitor Dynamics, 2021, Stem Cell Reports
  • Stem Cells, Hematopoiesis and Lineage Tracing: Transplantation-Centric Views and Beyond, 2022, Frontiers in Cell and Developmental Biology

Frequent coauthors collaborating with David Bryder include:

  • Anna Konturek-Cieśla
  • Ouyang Yuan
  • Qinyu Zhang
  • Mohamed Eldeeb
  • Charlotta Böiers

The scientist's work has appeared repeatedly in prominent venues such as:

  • Experimental Hematology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell Reports
  • Leukemia
  • Stem Cell Reports

Best Publications

  • Identification of Flt3(+) lympho-myeloid stem cells lacking erythro-megakaryocytic potential: A revised road map for adult blood lineage commitment

    Jörgen Adolfsson;Robert Månsson;Natalija Buza-Vidas;Anne Hultquist

  • Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age

    Derrick J Rossi;David Bryder;David Bryder;Jun Seita;Andre Nussenzweig

  • Cell intrinsic alterations underlie hematopoietic stem cell aging

    Derrick J. Rossi;David Bryder;Jacob M. Zahn;Henrik Ahlenius

  • Hematopoietic stem cells: the paradigmatic tissue-specific stem cell

    David Bryder;Derrick J. Rossi;Irving L. Weissman

  • Upregulation of Flt3 Expression within the Bone Marrow Lin−Sca1+c-kit+ Stem Cell Compartment Is Accompanied by Loss of Self-Renewal Capacity

    Jörgen Adolfsson;Ole Johan Borge;David Bryder;Kim Theilgaard-Mönch

  • Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion

    Isabel Beerman;Deepta Bhattacharya;Sasan Zandi;Mikael Sigvardsson

  • Elucidation of the phenotypic, functional, and molecular topography of a myeloerythroid progenitor cell hierarchy.

    Cornelis J.H. Pronk;Derrick J. Rossi;Robert Månsson;Joanne L. Attema

  • Transcription factor profiling in individual hematopoietic progenitors by digital RT-PCR

    Luigi Warren;David Bryder;Irving L. Weissman;Stephen R. Quake

  • Identification of Lin – Sca1 + kit + CD34 + Flt3 – short-term hematopoietic stem cells capable of rapidly reconstituting and rescuing myeloablated transplant recipients

    Liping Yang;David Bryder;Jörgen Adolfsson;Jens Martin Nygren

  • Efficient ablation of genes in human hematopoietic stem and effector cells using CRISPR/Cas9

    Pankaj Kumar Mandal;Pankaj Kumar Mandal;Leonardo Manuel Ramos Ferreira;Ryan Collins;Torsten B Meissner

  • Key Role of flt3 Ligand in Regulation of the Common Lymphoid Progenitor but Not in Maintenance of the Hematopoietic Stem Cell Pool.

    Ewa Sitnicka;David Bryder;Kim Theilgaard-Mönch;Natalija Buza-Vidas

  • NMD is essential for hematopoietic stem and progenitor cells and for eliminating by-products of programmed DNA rearrangements

    Joachim Weischenfeldt;Inge Damgaard;David Bryder;Kim Theilgaard-Mönch

  • Kit Regulates Maintenance of Quiescent Hematopoietic Stem Cells

    Lina A. Thorén;Karina Liuba;David Bryder;Jens Martin Nygren

  • Accumulating mitochondrial DNA mutations drive premature hematopoietic aging phenotypes distinct from physiological stem cell aging.

    Gudmundur L. Norddahl;Cornelis J. Pronk;Martin Wahlestedt;Gerd Sten

  • Complementary signaling through flt3 and interleukin-7 receptor alpha is indispensable for fetal and adult B cell genesis.

    Ewa Sitnicka;Cord Brakebusch;Inga-Lill Martensson;Marcus Svensson

  • Tumor necrosis factor restricts hematopoietic stem cell activity in mice: involvement of two distinct receptors

    Cornelis J.H. Pronk;Ole Petter Veiby;David Bryder;Sten Eirik W. Jacobsen;Sten Eirik W. Jacobsen

  • Hematopoietic stem cell quiescence attenuates DNA damage response and permits DNA damage accumulation during aging.

    Derrick J. Rossi;Jun Seita;Agnieszka Czechowicz;Deepta Bhattacharya

  • Gain-of-function SAMD9L mutations cause a syndrome of cytopenia, immunodeficiency, MDS and neurological symptoms

    Bianca Tesi;Josef Davidsson;Matthias Voss;Elisa Rahikkala;Elisa Rahikkala

  • Involvement and functional impairment of the CD34(+)CD38(-)Thy-1(+) hematopoietic stem cell pool in myelodysplastic syndromes with trisomy 8.

    Lars Nilsson;Ingbritt Åstrand-Grundström;Kristina Anderson;Ingrid Arvidsson

  • Tumor necrosis factor (TNF)-mediated activation of the p55 TNF receptor negatively regulates maintenance of cycling reconstituting human hematopoietic stem cells.

    Ingunn Dybedal;David Bryder;Anna Fossum;Leiv S. Rusten

Frequent Co-Authors

Mikael Sigvardsson
Mikael Sigvardsson Lund University
Derrick J. Rossi
Derrick J. Rossi Harvard University
Sten Eirik W. Jacobsen
Sten Eirik W. Jacobsen University of Oxford
Irving L. Weissman
Irving L. Weissman Stanford University
Stefan Karlsson
Stefan Karlsson Lund University
Lennart Nilsson
Lennart Nilsson Karolinska Institute
Thoas Fioretos
Thoas Fioretos Lund University
Yenan T. Bryceson
Yenan T. Bryceson Karolinska Institute
Jacques J. Peschon
Jacques J. Peschon Amgen (United States)
Zaal Kokaia
Zaal Kokaia Lund University

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