Derrick J. Rossi

Overview

Best Publications

• Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA

  Luigi Warren;Philip D. Manos;Philip D. Manos;Tim Ahfeldt;Tim Ahfeldt;Yuin-Han Loh

  3238
  Citations

• Somatic coding mutations in human induced pluripotent stem cells

  Athurva Gore;Zhe Li;Ho Lim Fung;Jessica E. Young

  1451
  Citations

• Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age

  Derrick J Rossi;David Bryder;David Bryder;Jun Seita;Andre Nussenzweig

  1254
  Citations

• Cell intrinsic alterations underlie hematopoietic stem cell aging

  Derrick J. Rossi;David Bryder;Jacob M. Zahn;Henrik Ahlenius

  1198
  Citations

• Stems cells and the pathways to aging and cancer.

  Derrick J. Rossi;Catriona H.M. Jamieson;Irving L. Weissman

  1064
  Citations

• Hematopoietic stem cells: the paradigmatic tissue-specific stem cell

  David Bryder;Derrick J. Rossi;Irving L. Weissman

  1056
  Citations

• Human bone marrow hematopoietic stem cells are increased in frequency and myeloid-biased with age

  Wendy W. Pang;Elizabeth A. Price;Debashis Sahoo;Isabel Beerman

  941
  Citations

• Human iPSC-Based Modeling of Late-Onset Disease via Progerin-Induced Aging

  Justine D. Miller;Yosif M. Ganat;Sarah Kishinevsky;Robert L. Bowman

  812
  Citations

• Comprehensive methylome map of lineage commitment from haematopoietic progenitors.

  Hong Ji;Lauren Ilyse richie Ehrlich;Jun Seita;Peter Murakami

  737
  Citations

• Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion

  Isabel Beerman;Deepta Bhattacharya;Sasan Zandi;Mikael Sigvardsson

  719
  Citations

• Modified mRNA directs the fate of heart progenitor cells and induces vascular regeneration after myocardial infarction.

  Lior Zangi;Kathy O Lui;Kathy O Lui;Alexander von Gise;Alexander von Gise;Qing Ma;Qing Ma

  717
  Citations

• Elucidation of the phenotypic, functional, and molecular topography of a myeloerythroid progenitor cell hierarchy.

  Cornelis J.H. Pronk;Derrick J. Rossi;Robert Månsson;Joanne L. Attema

  710
  Citations

• Incomplete DNA methylation underlies a transcriptional memory of somatic cells in human iPS cells

  Yuki Ohi;Han Qin;Chibo Hong;Laure Blouin

  667
  Citations

• Efficient ablation of genes in human hematopoietic stem and effector cells using CRISPR/Cas9

  Pankaj Kumar Mandal;Pankaj Kumar Mandal;Leonardo Manuel Ramos Ferreira;Ryan Collins;Torsten B Meissner

  573
  Citations

• Abnormal mesoderm patterning in mouse embryos mutant for the SH2 tyrosine phosphatase Shp‐2

  Tracy M. Saxton;Mark J Henkemeyer;Mark J Henkemeyer;Stéphan Gasca;Stéphan Gasca;Randy Shen

  570
  Citations

• Bone marrow-derived circulating endothelial precursors do not contribute to vascular endothelium and are not needed for tumor growth

  Susanna Purhonen;Jarmo Palm;Derrick Rossi;Nina Kaskenpää

  552
  Citations

• Proliferation-Dependent Alterations of the DNA Methylation Landscape Underlie Hematopoietic Stem Cell Aging

  Isabel Eleanor Beerman;Christoph Bock;Christoph Bock;Brian Scott Garrison;Brian Scott Garrison;Zachary D. Smith;Zachary D. Smith

  489
  Citations

• Quiescent hematopoietic stem cells accumulate DNA damage during aging that is repaired upon entry into cell cycle.

  Isabel Beerman;Jun Seita;Matthew A. Inlay;Matthew A. Inlay;Irving L. Weissman

  452
  Citations

• Vascular system defects and neuronal apoptosis in mice lacking Ras GTPase-activating protein

  Mark Henkemeyer;Derrick J. Rossi;Douglas P. Holmyard;Mira C. Puri

  438
  Citations

• DNA methylation dynamics during in vivo differentiation of blood and skin stem cells.

  Christoph Bock;Isabel Beerman;Isabel Beerman;Wen-Hui Lien;Zachary D. Smith;Zachary D. Smith

  399
  Citations