World's Best Scientists 2026 revealed!

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Molecular Biology

D-Index
97
Citations
55015
World Ranking
583
National Ranking
321

Medicine

D-Index
97
Citations
56136
World Ranking
9078
National Ranking
4682

Research.com Recognitions

  • 2018 - National Institutes of Health Director's Pioneer Award

Overview

Amy J. Wagers is affiliated with Harvard University in the United States and has contributed to a variety of research areas primarily within biochemistry, genetics, molecular biology, and medicine.

Their research spans several key subfields, including molecular biology, immunology, physiology, genetics, and aging. The scientist's work covers diverse topics such as muscle physiology and disorders, genetics related to aging and longevity in model organisms, GDF15 and related biomarkers, virus-based gene therapy research, single-cell and spatial transcriptomics, RNA research and splicing, as well as adipose tissue and metabolism.

Wagers has published numerous papers with notable recent publications including:

  • Loss of epigenetic information as a cause of mammalian aging, 2023, Cell
  • Directed evolution of a family of AAV capsid variants enabling potent muscle-directed gene delivery across species, 2021, Cell
  • The neutrotime transcriptional signature defines a single continuum of neutrophils across biological compartments, 2021, Nature Communications
  • Gut CD4+ T cell phenotypes are a continuum molded by microbes, not by TH archetypes, 2021, Nature Immunology
  • FOS licenses early events in stem cell activation driving skeletal muscle regeneration, 2021, Cell Reports

Frequent co-authors include Kathleen A. Messemer, Jason D. Buenrostro, Lee L. Rubin, Richard Lee, and Christophe Benoıst, reflecting collaborations that have appeared repeatedly in their body of work.

Wagers's publications most often appear in venues such as bioRxiv (Cold Spring Harbor Laboratory), Cell, Nature Immunology, Zenodo (CERN European Organization for Nuclear Research), and Nature Communications.

The scientist received the National Institutes of Health Director's Pioneer Award in 2018, recognizing contributions within their field.

Best Publications

  • Rejuvenation of aged progenitor cells by exposure to a young systemic environment

    Irina M. Conboy;Michael J. Conboy;Amy J. Wagers;Amy J. Wagers;Eric R. Girma

  • Haematopoietic stem cells adopt mature haematopoietic fates in ischaemic myocardium

    Leora B. Balsam;Amy J. Wagers;Julie L. Christensen;Theo Kofidis

  • The Immunological Genome Project: networks of gene expression in immune cells

    Tracy S P Heng;Michio W Painter;Kutlu Elpek;Veronika Lukacs-Kornek

  • Little evidence for developmental plasticity of adult hematopoietic stem cells.

    Amy J. Wagers;Richard I. Sherwood;Julie L. Christensen;Irving L. Weissman

  • Plasticity of Adult Stem Cells

    Amy J Wagers;Irving L Weissman

  • M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelination

    Veronique E. Miron;Amanda Boyd;Jing Wei Zhao;Tracy J. Yuen;Tracy J. Yuen

  • Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells

    Jose M. Polo;Susanna Liu;Maria Eugenia Figueroa;Warakorn Kulalert

  • Physiological migration of hematopoietic stem and progenitor cells.

    Douglas E. Wright;Amy J. Wagers;Anjali Pathak Gulati;Frances L. Johnson

  • Biology of hematopoietic stem cells and progenitors: implications for clinical application.

    Motonari Kondo;Amy J. Wagers;Markus G. Manz;Susan S. Prohaska

  • A Special Population of Regulatory T Cells Potentiates Muscle Repair

    Dalia Burzyn;Wilson Kuswanto;Dmitriy Kolodin;Jennifer L. Shadrach;Jennifer L. Shadrach

  • Langerhans cells renew in the skin throughout life under steady-state conditions

    Miriam Merad;Markus G. Manz;Holger Karsunky;Amy Wagers

  • Cell intrinsic alterations underlie hematopoietic stem cell aging

    Derrick J. Rossi;David Bryder;Jacob M. Zahn;Henrik Ahlenius

  • In vivo gene editing in dystrophic mouse muscle and muscle stem cells

    Mohammadsharif Tabebordbar;Kexian Zhu;Jason K. W. Cheng;Wei Leong Chew

  • Vascular and neurogenic rejuvenation of the aging mouse brain by young systemic factors.

    Lida Katsimpardi;Nadia K. Litterman;Pamela A. Schein;Christine M. Miller;Christine M. Miller

  • Growth Differentiation Factor 11 Is a Circulating Factor that Reverses Age-Related Cardiac Hypertrophy

    Francesco Loffredo;Matthew L. Steinhauser;Steven M. Jay;Joseph Gannon

  • No place like home: anatomy and function of the stem cell niche.

    D Leanne Jones;Amy J Wagers

  • Skin infection generates non-migratory memory CD8+ T(RM) cells providing global skin immunity.

    Xiaodong Jiang;Rachael A. Clark;Luzheng Liu;Amy J. Wagers

  • Restoring Systemic GDF11 Levels Reverses Age-Related Dysfunction in Mouse Skeletal Muscle

    M Sinha;Y. C. Jang;Y. C. Jang;Juhyun Oh;Juhyun Oh;Danika Mei Po Khong;Danika Mei Po Khong

  • BIOLOGY OF HEMATOPOIETIC STEM CELLS AND PROGENITORS: Implications for

    Motonari Kondo;Amy J. Wagers;Markus G. Manz;Susan S. Prohaska

  • In vivo gene editing in dystrophic mouse muscle and muscle stem cells

    M. Tabebordbar;K. Zhu;J. K. W. Cheng;W. L. Chew

Frequent Co-Authors

Irving L. Weissman
Irving L. Weissman Stanford University
Richard T. Lee
Richard T. Lee Harvard University
Diane Mathis
Diane Mathis Harvard University
Christophe Benoist
Christophe Benoist Harvard University
Derrick J. Rossi
Derrick J. Rossi Harvard University
Aviv Regev
Aviv Regev Genentech
Jill M. Goldstein
Jill M. Goldstein Harvard University
Lee L. Rubin
Lee L. Rubin Harvard University
Miriam Merad
Miriam Merad Icahn School of Medicine at Mount Sinai

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