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Biology and Biochemistry

D-Index
70
Citations
19703
World Ranking
6939
National Ranking
3197

Overview

Marilyn D. Resh is affiliated with Memorial Sloan Kettering Cancer Center in the United States. Their research primarily focuses on the field of Biochemistry, Genetics and Molecular Biology, with a particular emphasis on Molecular Biology, Biochemistry, Genetics, and Spectroscopy as subfields.

The main topics addressed in their work include:

  • Hedgehog Signaling Pathway Studies
  • Epigenetics and DNA Methylation
  • Lipid Metabolism and Biosynthesis
  • Ubiquitin and Proteasome Pathways
  • Genomics and Chromatin Dynamics
  • Cleft Lip and Palate Research
  • Cancer-related Gene Regulation

Resh's publication record includes papers from notable scientific venues such as Open Biology, Journal of Biological Chemistry, and BIO-PROTOCOL. Some recent publications are:

  • Palmitoylation of Hedgehog proteins by Hedgehog acyltransferase: roles in signalling and disease, 2021, Open Biology
  • Open Biology: overview for special issue on dynamics of protein fatty acylation, 2021, Open Biology
  • Hedgehog acyltransferase catalyzes a random sequential reaction and utilizes multiple fatty acyl-CoA substrates, 2022, Journal of Biological Chemistry
  • A Direct in vitro Fatty Acylation Assay for Hedgehog Acyltransferase, 2022, BIO-PROTOCOL

Frequent collaboration is evident with coauthor Adina Schonbrun, with whom Resh has shared authorship on multiple articles.

Overall, Resh's research involves biochemical mechanisms related to lipid modification enzymes and signaling pathways, particularly the Hedgehog signaling pathway. Their work integrates molecular biology techniques and biochemical assays to explore protein fatty acylation and its implications in cellular processes and disease contexts.

Best Publications

  • Fatty acylation of proteins: new insights into membrane targeting of myristoylated and palmitoylated proteins.

    Marilyn D. Resh

  • Myristylation and palmitylation of Src family members: The fats of the matter

    Marilyn D. Resh

  • CRYSTAL-STRUCTURE OF THE PHOSPHOTYROSINE RECOGNITION DOMAIN SH2 OF V-SRC COMPLEXED WITH TYROSINE-PHOSPHORYLATED PEPTIDES

    Gabriel Waksman;Dorothea Kominos;Scott C. Robertson;Scott C. Robertson;Nalin Pant

  • Identification of a membrane-binding domain within the amino-terminal region of human immunodeficiency virus type 1 Gag protein which interacts with acidic phospholipids.

    Wenjun Zhou;Leslie J. Parent;John W. Wills;Marilyn D. Resh

  • Trafficking and signaling by fatty-acylated and prenylated proteins

    Marilyn D Resh

  • Inhibition of protein palmitoylation, raft localization, and T cell signaling by 2-bromopalmitate and polyunsaturated fatty acids.

    Yael Webb;Luz Hermida-Matsumoto;Marilyn D. Resh

  • Palmitoylation of Ligands, Receptors, and Intracellular Signaling Molecules

    Marilyn D. Resh

  • Vanadate inhibits the red cell (Na + , K + ) ATPase from the cytoplasmic side

    Lewis C. Cantley;Marilyn D. Resh;Guido Guidotti

  • Localization of Human Immunodeficiency Virus Type 1 Gag and Env at the Plasma Membrane by Confocal Imaging

    Luz Hermida-Matsumoto;Marilyn D. Resh

  • Multimerization of Human Immunodeficiency Virus Type 1 Gag Promotes Its Localization to Barges, Raft-Like Membrane Microdomains

    O. Wolf Lindwasser;Marilyn D. Resh

  • Hhat is a palmitoylacyltransferase with specificity for N-palmitoylation of Sonic Hedgehog.

    John A. Buglino;Marilyn D. Resh

  • Differential membrane binding of the human immunodeficiency virus type 1 matrix protein.

    W Zhou;M D Resh

  • Amino-terminal basic residues of Src mediate membrane binding through electrostatic interaction with acidic phospholipids

    Catherine T. Sigal;Wenjun Zhou;Carolyn A. Buser;Stuart McLaughlin

  • Regulation of cellular signalling by fatty acid acylation and prenylation of signal transduction proteins.

    Marilyn D Resh

  • Heterogeneous fatty acylation of Src family kinases with polyunsaturated fatty acids regulates raft localization and signal transduction.

    Xiquan Liang;Arpi Nazarian;Hediye Erdjument-Bromage;William Bornmann

  • Fatty acylation of proteins: The long and the short of it.

    Marilyn D. Resh

  • Membrane Targeting of Lipid Modified Signal Transduction Proteins

    Marilyn D. Resh

  • Dual myristylation and palmitylation of Src family member p59fyn affects subcellular localization.

    L Alland;S M Peseckis;R E Atherton;L Berthiaume

  • Morphological Differentiation of Oligodendrocytes Requires Activation of Fyn Tyrosine Kinase

    Donna J. Osterhout;Amy Wolven;Rebecca M. Wolf;Marilyn D. Resh

  • Cholesterol Depletion from the Plasma Membrane Triggers Ligand-independent Activation of the Epidermal Growth Factor Receptor

    Xu Chen;Marilyn D. Resh

Frequent Co-Authors

Bayard D. Clarkson
Bayard D. Clarkson Memorial Sloan Kettering Cancer Center
Stuart McLaughlin
Stuart McLaughlin Stony Brook University
Eric C. Holland
Eric C. Holland Fred Hutchinson Cancer Research Center
John W. Wills
John W. Wills Pennsylvania State University
Hediye Erdjument-Bromage
Hediye Erdjument-Bromage New York University
Christelle Borel
Christelle Borel University of Geneva
Moses V. Chao
Moses V. Chao New York University
Michel Guipponi
Michel Guipponi University of Geneva
Laurence Faivre
Laurence Faivre University of Burgundy
Stylianos E. Antonarakis
Stylianos E. Antonarakis University of Geneva

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