World's Best Scientists 2026 revealed!
Hediye Erdjument-Bromage

Hediye Erdjument-Bromage

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Best Female Scientists
2025
Award Badge
Molecular Biology
USA
2026

D-Index & Metrics

Best Female Scientists

D-Index
148
Citations
107308
World Ranking
162
National Ranking
99

Molecular Biology

D-Index
149
Citations
107536
World Ranking
86
National Ranking
54

Research.com Recognitions

  • 2026 - Research.com Molecular Biology in United States Leader Award
  • 2025 - Research.com Best Female Scientists Award
  • 2025 - Research.com Molecular Biology in United States Leader Award
  • 2023 - Research.com Molecular Biology in United States Leader Award

Overview

Hediye Erdjument-Bromage is affiliated with New York University in the United States. Their research primarily focuses on Biochemistry, Genetics and Molecular Biology, with an emphasis on Molecular Biology, Cell Biology, Physiology, Cellular and Molecular Neuroscience, and Immunology as subfields.

Their work covers several scientific topics including cellular transport and secretion, mitochondrial function and pathology, extracellular vesicles in disease, Alzheimer's disease research and treatments, epigenetics and DNA methylation, receptor mechanisms and signaling, and ATP synthase and ATPases research.

Frequent co-authors in Erdjument-Bromage's collaborations include Thomas A. Neubert, Paul Tempst, Palak Panchal, Anna Rodina, and Gabriela Chiosis.

They have contributed to publications in venues such as bioRxiv (Cold Spring Harbor Laboratory), UNC Libraries, Nature Communications, Cell Reports, and Arteriosclerosis Thrombosis and Vascular Biology.

Recent papers authored or co-authored by Erdjument-Bromage include the following:

  • "Mitovesicles are a novel population of extracellular vesicles of mitochondrial origin altered in Down syndrome," 2021, Science Advances
  • "The epichaperome is a mediator of toxic hippocampal stress and leads to protein connectivity-based dysfunction," 2020, Nature Communications
  • "Lysosomal dysfunction in Down syndrome and Alzheimer mouse models is caused by v-ATPase inhibition by Tyr 682-phosphorylated APP βCTF," 2023, Science Advances
  • "Molecular Stressors Engender Protein Connectivity Dysfunction through Aberrant N-Glycosylation of a Chaperone," 2020, Cell Reports
  • "Structures of LRP2 reveal a molecular machine for endocytosis," 2023, Cell

Best Publications

  • Role of Histone H3 Lysine 27 Methylation in Polycomb-Group Silencing

    Ru Cao;Liangjun Wang;Hengbin Wang;Li Xia

  • SNAP receptors implicated in vesicle targeting and fusion

    Thomas Söllner;Sidney W. Whiteheart;Michael Brunner;Hediye Erdjument-Bromage

  • mTOR Interacts with Raptor to Form a Nutrient-Sensitive Complex that Signals to the Cell Growth Machinery

    Do Hyung Kim;Dos D. Sarbassov;Siraj M. Ali;Jessie E. King

  • Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton.

    Dos D. Sarbassov;Siraj M Ali;Do-Hyung Kim;David A Guertin

  • Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals

    Kornelia Polyak;Mong Hong Lee;Hediye Erdjument-Bromage;Andrew Koff

  • PRDM16 controls a brown fat/skeletal muscle switch

    Patrick Seale;Bryan Bjork;Wenli Yang;Shingo Kajimura

  • Histone demethylation by a family of JmjC domain-containing proteins

    Yu Ichi Tsukada;Jia Fang;Jia Fang;Hediye Erdjument-Bromage;Maria E. Warren

  • Role of histone H2A ubiquitination in Polycomb silencing

    Hengbin Wang;Liangjun Wang;Hediye Erdjument-Bromage;Miguel Vidal

  • RAFT1: a mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs.

    David M. Sabatini;Hediye Erdjument-Bromage;Mary Lui;Paul Tempst

  • Histone methyltransferase activity associated with a human multiprotein complex containing the Enhancer of Zeste protein

    Andrei Kuzmichev;Kenichi Nishioka;Hediye Erdjument-Bromage;Paul Tempst

  • TLR signalling augments macrophage bactericidal activity through mitochondrial ROS

    A. Phillip West;Igor E. Brodsky;Igor E. Brodsky;Christoph Rahner;Dong Kyun Woo

  • DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA.

    Steen K.T. Ooi;Chen Qiu;Emily Bernstein;Keqin Li

  • Protein S-nitrosylation: a physiological signal for neuronal nitric oxide.

    Samie R. Jaffrey;Hediye Erdjument-Bromage;Christopher D. Ferris;Paul Tempst

  • Phosphorylation and Functional Inactivation of TSC2 by Erk: Implications for Tuberous Sclerosis and Cancer Pathogenesis

    Li Ma;Zhenbang Chen;Hediye Erdjument-Bromage;Paul Tempst;Paul Tempst

  • Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation

    Yi Zhang;Huck-Hui Ng;Hediye Erdjument-Bromage;Paul Tempst

  • Protein Kinase B Kinases That Mediate Phosphatidylinositol 3,4,5-Trisphosphate-Dependent Activation of Protein Kinase B

    Len Stephens;Karen Anderson;David Stokoe;Hediye Erdjument-Bromage

  • Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1/Fas death.

    Atan Gross;Xiao Ming Yin;Kun Wang;Michael C. Wei

  • GβL, a Positive Regulator of the Rapamycin-Sensitive Pathway Required for the Nutrient-Sensitive Interaction between Raptor and mTOR

    Do Hyung Kim;Dos D. Sarbassov;Siraj M. Ali;Robert R. Latek

  • MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex.

    Huck-Hui Ng;Yi Zhang;Brian Hendrich;Colin A Johnson

  • Human SirT1 Interacts with Histone H1 and Promotes Formation of Facultative Heterochromatin

    Alejandro Vaquero;Michael Scher;Donghoon Lee;Hediye Erdjument-Bromage

Frequent Co-Authors

Paul Tempst
Paul Tempst Memorial Sloan Kettering Cancer Center
Yi Zhang
Yi Zhang Harvard University
Danny Reinberg
Danny Reinberg University of Miami
Bradley R. Cairns
Bradley R. Cairns University of Utah
Gabriela Chiosis
Gabriela Chiosis Memorial Sloan Kettering Cancer Center
Jesper Q. Svejstrup
Jesper Q. Svejstrup University of Copenhagen
Ari Melnick
Ari Melnick Cornell University
Roger D. Kornberg
Roger D. Kornberg Stanford University
Pier Paolo Pandolfi
Pier Paolo Pandolfi Beth Israel Deaconess Medical Center
C. David Allis
C. David Allis Rockefeller University

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