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Jonathan A. Ellman

Jonathan A. Ellman

D-Index & Metrics

Chemistry

D-Index
124
Citations
54648
World Ranking
418
National Ranking
181

Research.com Recognitions

  • 2015 - Fellow of the American Academy of Arts and Sciences
  • 2006 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 1994 - Fellow of Alfred P. Sloan Foundation

Overview

Jonathan A. Ellman is affiliated with Yale University in the United States. Their research primarily spans the fields of Chemistry and Materials Science, with a notable emphasis on Organic Chemistry and Materials Chemistry. Additional areas of study include Molecular Biology, Inorganic Chemistry, and Pharmaceutical Science.

The scientist's work focuses on several main topics, including Catalytic C-H Functionalization Methods, Synthesis and Catalytic Reactions, Crystallization and Solubility Studies, X-ray Diffraction in Crystallography, Sulfur-Based Synthesis Techniques, Cyclopropane Reaction Mechanisms, and Asymmetric Hydrogenation and Catalysis.

Jonathan A. Ellman has contributed to numerous publications, with frequent articles appearing in several venues. These include:

  • The Cambridge Structural Database (24 publications)
  • Organic Letters (13 publications)
  • Angewandte Chemie International Edition (6 publications)
  • Journal of the American Chemical Society (5 publications)
  • Angewandte Chemie (5 publications)

They have coauthored multiple papers with other researchers. Frequent collaborators include Brandon Q. Mercado, Nathaniel S. Greenwood, Danielle N. Confair, Andrew T. Champlin, and James M. Mayer.

Some recent notable papers include:

  • Bespoke library docking for 5-HT2A receptor agonists with antidepressant activity, 2022, Nature
  • Catalytic Enantioselective Sulfur Alkylation of Sulfenamides for the Asymmetric Synthesis of Sulfoximines, 2022, Journal of the American Chemical Society
  • Highly Diastereoselective Functionalization of Piperidines by Photoredox-Catalyzed α-Amino C-H Arylation and Epimerization, 2020, Journal of the American Chemical Society
  • Rhodium-Catalyzed C-H Alkenylation/Electrocyclization Cascade Provides Dihydropyridines That Serve as Versatile Intermediates to Diverse Nitrogen Heterocycles, 2021, Accounts of Chemical Research
  • Sulfur-Arylation of Sulfenamides via Chan-Lam Coupling with Boronic Acids: Access to High Oxidation State Sulfur Pharmacophores, 2023, Organic Letters

Jonathan A. Ellman has received several awards recognizing their contributions in scientific research. These include being named a Fellow of the American Academy of Arts and Sciences in 2015, a Fellow of the American Association for the Advancement of Science (AAAS) in 2006, and a Fellow of the Alfred P. Sloan Foundation in 1994.

Best Publications

  • Rhodium-Catalyzed C-C Bond Formation via Heteroatom-Directed C-H Bond Activation

    Denise A. Colby;Robert G. Bergman;Jonathan A. Ellman

  • Synthesis and Applications of Small Molecule Libraries.

    Lorin A. Thompson;Jonathan A. Ellman

  • Rhodium catalyzed chelation-assisted C-H bond functionalization reactions

    Denise A. Colby;Andy S. Tsai;Robert G. Bergman;Jonathan A. Ellman

  • Synthesis and Applications of tert-Butanesulfinamide

    MaryAnn T. Robak;Melissa A. Herbage;Jonathan A. Ellman

  • Solid phase and combinatorial synthesis of compounds on a solid support

    Jonathan A. Ellman

  • N-tert-butanesulfinyl imines: versatile intermediates for the asymmetric synthesis of amines.

    Jonathan A. Ellman;Timothy D. Owens;Tony P. Tang

  • Direct Functionalization of Nitrogen Heterocycles via Rh-Catalyzed C−H Bond Activation

    Jared C. Lewis;Robert G. Bergman;Jonathan A. Ellman

  • A general and expedient method for the solid-phase synthesis of 1,4-benzodiazepine derivatives

    Barry A. Bunin;Jonathan A. Ellman

  • Contrasteric carboximide hydrolysis with lithium hydroperoxide

    David A. Evans;Thomas C. Britton;Jon A. Ellman

  • Catalytic Asymmetric Synthesis of tert-Butanesulfinamide. Application to the Asymmetric Synthesis of Amines

    Guangcheng Liu;Derek A. Cogan;Jonathan A. Ellman

  • Transition-Metal-Catalyzed C–H Bond Addition to Carbonyls, Imines, and Related Polarized π Bonds

    Joshua R. Hummel;Jeffrey A. Boerth;Jonathan A. Ellman

  • Rapid and general profiling of protease specificity by using combinatorial fluorogenic substrate libraries

    Jennifer L. Harris;Bradley J. Backes;Francesco Leonetti;Sami Mahrus

  • Synthesis of Enantiomerically Pure N-tert-Butanesulfinyl Imines (tert-Butanesulfinimines) by the Direct Condensation of tert-Butanesulfinamide with Aldehydes and Ketones

    Guangcheng Liu;Derek A. Cogan;Timothy D. Owens;Tony P. Tang

  • The asymmetric synthesis of .alpha.-amino acids. Electrophilic azidation of chiral imide enolates, a practical approach to the synthesis of (R)- and (S)-.alpha.-azido carboxylic acids

    David A. Evans;Thomas C. Britton;Jonathan A. Ellman;Roberta L. Dorow

  • Cobalt(III)-catalyzed synthesis of indazoles and furans by C-H bond functionalization/addition/cyclization cascades.

    Joshua R. Hummel;Jonathan A. Ellman

  • Substrate profiling of cysteine proteases using a combinatorial peptide library identifies functionally unique specificities.

    Youngchool Choe;Francesco Leonetti;Doron C. Greenbaum;Fabien Lecaille

  • The combinatorial synthesis and chemical and biological evaluation of a 1,4-benzodiazepine library

    Barry A. Bunin;Matthew J. Plunkett;Jonathan A. Ellman

  • Asymmetric synthesis of chiral amines by highly diastereoselective 1,2-additions of organometallic reagents to N-tert-butanesulfinyl imines

    Derek A. Cogan;Guangcheng Liu;Jonathan Ellman

  • Catalytic Asymmetric Oxidation of tert-Butyl Disulfide. Synthesis of tert-Butanesulfinamides, tert-Butyl Sulfoxides, and tert-Butanesulfinimines

    Derek A. Cogan;Guangcheng Liu;Kyungjin Kim;Bradley J. Backes

  • Catalytic C-O Bond Cleavage of 2-Aryloxy-1-arylethanols and Its Application to the Depolymerization of Lignin-Related Polymers

    Jason M. Nichols;Lee M. Bishop;Robert G. Bergman;Jonathan A. Ellman

Frequent Co-Authors

Robert G. Bergman
Robert G. Bergman University of California, Berkeley
Brandon Q. Mercado
Brandon Q. Mercado Yale University
Charles S. Craik
Charles S. Craik University of California, San Francisco
David A. Evans
David A. Evans Harvard University
Paul J. Lombroso
Paul J. Lombroso Yale University
Angus C. Nairn
Angus C. Nairn Yale University
Irwin D. Kuntz
Irwin D. Kuntz University of California, San Francisco
Peter G. Schultz
Peter G. Schultz Scripps Research Institute
Matthew Bogyo
Matthew Bogyo Stanford University
Daniel J. Weix
Daniel J. Weix University of Wisconsin–Madison

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