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Charles S. Craik

D-Index & Metrics

Biology and Biochemistry

D-Index
107
Citations
40501
World Ranking
1108
National Ranking
664

Chemistry

D-Index
95
Citations
35340
World Ranking
1611
National Ranking
616

Charles S. Craik publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Charles S. Craik sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 477 publications — 94th percentile

94% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Charles S. Craik D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Charles S. Craik sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 107 D-Index — 95th percentile

95% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Research.com Recognitions

  • 2017 - Fellow of the American Academy of Arts and Sciences
  • 2014 - Fellow, National Academy of Inventors
  • 2010 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Charles S. Craik is affiliated with the University of California, San Francisco in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics, and Molecular Biology. Within these broad fields, their work focuses on subfields including Molecular Biology, Infectious Diseases, Oncology, Epidemiology, and Radiology, Nuclear Medicine, and Imaging.

The main topics Charles S. Craik investigates include SARS-CoV-2 and COVID-19 Research, Computational Drug Discovery Methods, Monoclonal and Polyclonal Antibodies Research, COVID-19 Clinical Research Studies, Pancreatic and Hepatic Oncology Research, Antifungal Resistance and Susceptibility, and Fungal Infections and Studies.

They have published in multiple venues, notably with a concentration of papers in bioRxiv (Cold Spring Harbor Laboratory). Other frequent publication venues consist of the Journal of Medicinal Chemistry, Nature Communications, Science, and the Journal of Biological Chemistry.

Some of their recent research outputs include:

  • A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing, 2020, bioRxiv (Cold Spring Harbor Laboratory)
  • Characterising proteolysis during SARS-CoV-2 infection identifies viral cleavage sites and cellular targets with therapeutic potential, 2021, Nature Communications
  • A covalent inhibitor of K-Ras(G12C) induces MHC class I presentation of haptenated peptide neoepitopes targetable by immunotherapy, 2022, Cancer Cell
  • A novel class of TMPRSS2 inhibitors potently block SARS-CoV-2 and MERS-CoV viral entry and protect human epithelial lung cells, 2021, Proceedings of the National Academy of Sciences
  • Structural and mechanistic basis of the EMC-dependent biogenesis of distinct transmembrane clients, 2020, eLife

Charles S. Craik frequently collaborates with a group of coauthors, including André Luiz Lourenço, Markus-Frederik Bohn, Anthony J. O'Donoghue, Brian K. Shoichet, and Conner Bardine.

Throughout their career, they have been recognized by several fellowships: Fellow of the American Academy of Arts and Sciences (2017), Fellow of the National Academy of Inventors (2014), and Fellow of the American Association for the Advancement of Science (AAAS) (2010).

Best Publications

  • A SARS-CoV-2 protein interaction map reveals targets for drug repurposing.

    David E. Gordon;Gwendolyn M. Jang;Mehdi Bouhaddou;Jiewei Xu

  • Structural basis of substrate specificity in the serine proteases

    John J. Perona;Charles S. Craik

  • Global landscape of HIV-human protein complexes

    Stefanie Jäger;Peter Cimermancic;Peter Cimermancic;Natali Gulbahce;Natali Gulbahce;Jeffrey R. Johnson;Jeffrey R. Johnson;Jeffrey R. Johnson

  • Rapid and general profiling of protease specificity by using combinatorial fluorogenic substrate libraries

    Jennifer L. Harris;Bradley J. Backes;Francesco Leonetti;Sami Mahrus

  • Cellular localization of membrane-type serine protease 1 and identification of protease-activated receptor-2 and single-chain urokinase-type plasminogen activator as substrates.

    Toshihiko Takeuchi;Jennifer L. Harris;Wei Huang;Kelly W. Yan

  • Replacement of lysine residue 1030 in the putative ATP-binding region of the insulin receptor abolishes insulin- and antibody-stimulated glucose uptake and receptor kinase activity

    Yousuke Ebina;Eiichi Araki;Masato Taira;Fumio Shimada

  • Redesigning trypsin: alteration of substrate specificity

    Charles S. Craik;Corey Largman;Thomas Fletcher;Steven Roczniak

  • Substrate profiling of cysteine proteases using a combinatorial peptide library identifies functionally unique specificities.

    Youngchool Choe;Francesco Leonetti;Doron C. Greenbaum;Fabien Lecaille

  • The Androgen-Regulated Protease TMPRSS2 Activates a Proteolytic Cascade Involving Components of the Tumor Microenvironment and Promotes Prostate Cancer Metastasis

    Jared M. Lucas;Cynthia Heinlein;Tom Kim;Susana A. Hernandez

  • Evolutionary Divergence of Substrate Specificity within the Chymotrypsin-like Serine Protease Fold

    John J. Perona;Charles S. Craik

  • Vif hijacks CBF-β to degrade APOBEC3G and promote HIV-1 infection

    Stefanie Jäger;Dong Young Kim;Judd F. Hultquist;Keisuke Shindo

  • The Catalytic Role of the Active Site Aspartic Acid in Serine Proteases

    Charles S. Craik;Steven Roczniak;Corey Largman;William J. Rutter

  • Cathepsin G activates protease-activated receptor-4 in human platelets.

    Gilberto R. Sambrano;Wei Huang;Tatjana Faruqi;Sami Mahrus

  • The sequence, organization, and expression of the major cysteine protease (cruzain) from Trypanosoma cruzi.

    A.E. Eakin;A.A. Mills;G Harth;J.H. McKerrow

  • Structure-based design of nonpeptide inhibitors specific for the human immunodeficiency virus 1 protease.

    R L DesJarlais;G L Seibel;I D Kuntz;P S Furth

  • Cryo-EM structures of the TMEM16A calcium-activated chloride channel.

    Shangyu Dang;Shengjie Feng;Jason Tien;Christian Joseph Peters

  • Inhibition of the HIV-1 and HIV-2 proteases by curcumin and curcumin boron complexes.

    Zhihua Sui;Rafael Salto;Jia Li;Charles Craik

  • Vinyl sulfones as antiparasitic agents and a structural basis for drug design.

    Iain D. Kerr;Ji Hyun Lee;Christopher J. Farady;Rachael Marion

  • Synthesis of positional-scanning libraries of fluorogenic peptide substrates to define the extended substrate specificity of plasmin and thrombin.

    Bradley J. Backes;Jennifer L. Harris;Francesco Leonetti;Charles S. Craik

  • The crystal structure of cruzain: a therapeutic target for Chagas' disease.

    Mary E. McGrath;Ann E. Eakin;Juan C. Engel;James H. McKerrow

  • Evolutionary Divergence of Substrate Specificity within the Chymotrypsin-like

    John J. Perona;Charles S. Craik

Frequent Co-Authors

Robert J. Fletterick
Robert J. Fletterick University of California, San Francisco
James H. McKerrow
James H. McKerrow University of California, San Diego
William J. Rutter
William J. Rutter University of California, San Francisco
Robert M. Stroud
Robert M. Stroud University of California, San Francisco
Conor R. Caffrey
Conor R. Caffrey University of Montana
Andrej Sali
Andrej Sali University of California, San Francisco
John J. Perona
John J. Perona Portland State University
Jonathan A. Ellman
Jonathan A. Ellman Yale University
George H. Caughey
George H. Caughey University of California, San Francisco
Yifan Cheng
Yifan Cheng University of California, San Francisco

External Links

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