World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
61
Citations
13686
World Ranking
11322
National Ranking
4903

Overview

Conor R. Caffrey is affiliated with the University of Montana in the United States, focusing primarily on medicine with a specialized interest in parasitology and related fields. Their research encompasses a range of subfields including parasitology, public health, environmental and occupational health, organic chemistry, epidemiology, and molecular biology.

The scientist has contributed to multiple topics within biomedical research, emphasizing parasites and host interactions, research on leishmaniasis, studies of Trypanosoma species, parasite biology, helminth infection and control, synthesis and biological evaluation, as well as ubiquitin and proteasome pathways. The breadth of these topics reflects an interdisciplinary approach integrating biology and chemistry to address infectious diseases and parasite biology.

Among their recent published papers are:

  • A single-cell RNA-seq atlas of Schistosoma mansoni identifies a key regulator of blood feeding, 2020, Science
  • Structure-Based Optimization of Quinazolines as Cruzain and TbrCATL Inhibitors, 2021, Journal of Medicinal Chemistry
  • Perspective on Schistosomiasis Drug Discovery: Highlights from a Schistosomiasis Drug Discovery Workshop at Wellcome Collection, London, September 2022, 2023, ACS Infectious Diseases
  • Protein-protein interactions: developing small-molecule inhibitors/stabilizers through covalent strategies, 2023, Trends in Pharmacological Sciences
  • A Machine Learning Strategy for Drug Discovery Identifies Anti-Schistosomal Small Molecules, 2021, ACS Infectious Diseases

Frequent collaborators contributing to their research include Lawrence J. Liu, Karol R. Francisco, Nelly El-Sakkary, Carlo Ballatore, and Anthony J. O'Donoghue. The scientist's work has been published extensively in venues such as ACS Infectious Diseases, bioRxiv (Cold Spring Harbor Laboratory), ACS Omega, ChemMedChem, and the Journal of Medicinal Chemistry.

This publication record indicates a consistent presence in journals focused on infectious diseases, medicinal chemistry, and pharmacology, highlighting their contribution to advancing knowledge in these areas.

Best Publications

  • The genome of the blood fluke Schistosoma mansoni

    Matthew Berriman;Brian J. Haas;Brian J. Haas;Philip T. LoVerde;R. Alan Wilson

  • Synthesis and Structure−Activity Relationship Study of Potent Trypanocidal Thio Semicarbazone Inhibitors of the Trypanosomal Cysteine Protease Cruzain

    Xiaohui Du;Chun Guo;Elizabeth Hansell;Patricia S Doyle

  • PROTEASES IN PARASITIC DISEASES

    James H McKerrow;Conor Caffrey;Ben Kelly;P'ng Loke

  • Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.

    Wesley C. Van Voorhis;John H. Adams;Roberto Adelfio;Roberto Adelfio;Vida Ahyong

  • Chemotherapy of schistosomiasis: present and future.

    Conor R Caffrey

  • Synthesis and structure-activity relationships of parasiticidal thiosemicarbazone cysteine protease inhibitors against Plasmodium falciparum, Trypanosoma brucei, and Trypanosoma cruzi.

    Doron C. Greenbaum;Zachary Mackey;Elizabeth Hansell;Patricia Doyle

  • Schistosomiasis Mansoni: Novel Chemotherapy Using a Cysteine Protease Inhibitor

    Maha-Hamadien Abdulla;Kee-Chong Lim;Mohammed Sajid;James H McKerrow

  • Vinyl sulfones as antiparasitic agents and a structural basis for drug design.

    Iain D. Kerr;Ji Hyun Lee;Christopher J. Farady;Rachael Marion

  • Cysteine protease inhibitors as chemotherapy for parasitic infections

    James H McKerrow;Juan C Engel;Conor R Caffrey

  • From innovation to application: social-ecological context, diagnostics, drugs and integrated control of schistosomiasis

    Jürg Utzinger;Jürg Utzinger;Eliézer K. N’Goran;Conor R. Caffrey;Jennifer Keiser;Jennifer Keiser

  • A multienzyme network functions in intestinal protein digestion by a platyhelminth parasite.

    Melaine Delcroix;Mohammed Sajid;Conor R Caffrey;Kee-C Lim

  • Caenorhabditis elegans is a useful model for anthelmintic discovery.

    Andrew R. Burns;Genna M. Luciani;Gabriel Musso;Gabriel Musso;Rachel Bagg

  • Active site mapping, biochemical properties and subcellular localization of rhodesain, the major cysteine protease of Trypanosoma brucei rhodesiense.

    Conor R Caffrey;Elizabeth Hansell;Kimberley D Lucas;Linda S Brinen

  • Drug Discovery for Schistosomiasis: Hit and Lead Compounds Identified in a Library of Known Drugs by Medium-Throughput Phenotypic Screening

    Maha Hamadien Abdulla;Debbie S. Ruelas;Brian Wolff;June Snedecor

  • New insights into the machinery of blood digestion by ticks

    Daniel Sojka;Zdeněk Franta;Martin Horn;Conor R. Caffrey

  • Blood 'n' guts: an update on schistosome digestive peptidases.

    Conor R. Caffrey;James H. McKerrow;Jason P. Salter;Mohammed Sajid

  • Hemoglobin Digestion in Blood-Feeding Ticks: Mapping a Multipeptidase Pathway by Functional Proteomics

    Martin Horn;Martina Nussbaumerová;Miloslav Šanda;Zuzana Kovářová;Zuzana Kovářová

  • Functional expression and characterization of Schistosoma mansoni cathepsin B and its trans-activation by an endogenous asparaginyl endopeptidase.

    Mohammed Sajid;James H McKerrow;Elizabeth Hansell;Mary A Mathieu

  • RNA interference in Schistosoma mansoni schistosomula: selectivity, sensitivity and operation for larger-scale screening.

    Saša Štefanić;Jan Dvořák;Martin Horn;Simon Braschi

  • A single-cell RNA-seq atlas of Schistosoma mansoni identifies a key regulator of blood feeding.

    George Wendt;Lu Zhao;Rui Chen;Chenxi Liu

Frequent Co-Authors

James H. McKerrow
James H. McKerrow University of California, San Diego
Mohammed Sajid
Mohammed Sajid Leiden University Medical Center
Charles S. Craik
Charles S. Craik University of California, San Francisco
Jennifer Keiser
Jennifer Keiser Swiss Tropical and Public Health Institute
Andreas Ruppel
Andreas Ruppel Heidelberg University
John P. Dalton
John P. Dalton University of Galway
R. Kiplin Guy
R. Kiplin Guy University of Kentucky
Matthew Bogyo
Matthew Bogyo Stanford University
Michelle R. Arkin
Michelle R. Arkin University of California, San Francisco
Graham A. Hitman
Graham A. Hitman Queen Mary University of London

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring Biology and Biochemistry can open doors to diverse and rewarding career opportunities, and online degrees offer a flexible route to gain the expertise needed. For those interested in the intersection of biology and wellness, consider pursuing an online nutrition degree, which equips you for roles in health promotion, food science, and clinical nutrition.

If your interests expand beyond science into healthcare leadership, accredited options such as online mha programs cahme accredited provide a strong foundation for hospital or healthcare administration careers. Advanced practitioners can also enhance their qualifications with specialized graduate programs. For example, online dnp programs without clinicals are ideal for healthcare professionals seeking to expand their expertise without direct patient care requirements.

Additionally, those aiming for leadership in healthcare systems or research may consider online doctoral programs healthcare administration. Each of these pathways offers unique opportunities, whether your goal is hands-on science, patient advocacy, or strategic leadership in the health sector.

Best Scientists Citing Conor R. Caffrey

Trending Scientists

Recently Published Articles