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Karl F. Hoffmann

D-Index & Metrics

Biology and Biochemistry

D-Index
46
Citations
19284
World Ranking
18805
National Ranking
1466

Karl F. Hoffmann publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Karl F. Hoffmann sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 413 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 848 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 949 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 840 scientists 207–216 publications: 733 scientists 217–226 publications: 708 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 417 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 196 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 59 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 112 publications — 9th percentile

9% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Karl F. Hoffmann D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Karl F. Hoffmann sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 316 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 899 scientists 52–53 D-Index: 1,025 scientists 54–55 D-Index: 1,149 scientists 56–57 D-Index: 1,235 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,162 scientists 62–63 D-Index: 1,130 scientists 64–65 D-Index: 1,031 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 714 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 71 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 46 D-Index — 4th percentile

4% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Karl F. Hoffmann is affiliated with Aberystwyth University in the United Kingdom. Their research primarily spans the fields of Immunology and Microbiology, with 33 publications, and Medicine, also with 33 publications. Their work focuses heavily on Parasitology, a subfield reflected in 33 of their publications, along with areas such as Molecular Biology, Public Health, Environmental and Occupational Health, Ecology, and Infectious Diseases.

The main topics of Karl F. Hoffmann's research include Parasites and Host Interactions, covered in 66 publications, Parasite Biology and Host Interactions, Research on Leishmaniasis Studies, Helminth Infection and Control, Malaria Research and Control, Extracellular Vesicles in Disease, and Pneumocystis jirovecii Pneumonia Detection and Treatment.

Recent publications illustrate the focus on parasitic diseases and extracellular vesicles in this context. Notable papers include:

  • Large-scale RNAi screening uncovers therapeutic targets in the parasite Schistosoma mansoni, 2020, Science
  • DC-SIGN mediated internalisation of glycosylated extracellular vesicles from Schistosoma mansoni increases activation of monocyte-derived dendritic cells, 2020, Journal of Extracellular Vesicles
  • Special considerations for studies of extracellular vesicles from parasitic helminths: A community-led roadmap to increase rigour and reproducibility, 2023, Journal of Extracellular Vesicles
  • Perspective on Schistosomiasis Drug Discovery: Highlights from a Schistosomiasis Drug Discovery Workshop at Wellcome Collection, London, September 2022, 2023, ACS Infectious Diseases
  • Schistosoma mansoni α-N-acetylgalactosaminidase (SmNAGAL) regulates coordinated parasite movement and egg production, 2022, PLoS Pathogens

Karl F. Hoffmann has collaborated frequently with several researchers, including Josephine Forde-Thomas, Gilda Padalino, Iain W. Chalmers, Helen Whiteland, and Andrea Brancale. Their repeated collaborations suggest ongoing partnerships focused on parasitology and related biomedical fields.

Publication venues for Hoffmann's work include journals and platforms such as bioRxiv (Cold Spring Harbor Laboratory), where nine of their papers are available, Wellcome Open Research with four publications, ACS Infectious Diseases and PLoS Neglected Tropical Diseases each with three, and the Journal of Extracellular Vesicles with two.

Best Publications

  • Minimal information for studies of extracellular vesicles 2018 (MISEV2018) : a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

    Clotilde Théry;Kenneth W. Witwer;Elena Aikawa;Maria Jose Alcaraz

  • The Role of Interleukin (IL)-10 in the Persistence of Leishmania major in the Skin after Healing and the Therapeutic Potential of Anti–IL-10 Receptor Antibody for Sterile Cure

    Yasmine Belkaid;Karl F. Hoffmann;Susana Mendez;Shaden Kamhawi

  • IL-10 and the Dangers of Immune Polarization: Excessive Type 1 and Type 2 Cytokine Responses Induce Distinct Forms of Lethal Immunopathology in Murine Schistosomiasis

    Karl F. Hoffmann;Allen W. Cheever;Thomas A. Wynn

  • IL-10 is critical for host resistance and survival during gastrointestinal helminth infection

    Lisa R. Schopf;Karl F. Hoffmann;Allen W. Cheever;Joseph F. Urban

  • Whole genome analysis of a schistosomiasis-transmitting freshwater snail.

    Coen M Adema;Ladeana W Hillier;Catherine S Jones;Eric S Loker

  • Studies with Double Cytokine-Deficient Mice Reveal That Highly Polarized Th1- and Th2-Type Cytokine and Antibody Responses Contribute Equally to Vaccine-Induced Immunity to Schistosoma mansoni

    Karl F. Hoffmann;Stephanie L. James;Allen W. Cheever;Thomas A. Wynn

  • Cytokine-mediated host responses during schistosome infections; walking the fine line between immunological control and immunopathology.

    Karl F Hoffmann;Thomas A Wynn;David W Dunne

  • Protein and small non-coding RNA-enriched extracellular vesicles are released by the pathogenic blood fluke Schistosoma mansoni

    Fanny C. Nowacki;Martin T. Swain;Oleg I. Klychnikov;Umar Niazi

  • Immunopathology of schistosomiasis mansoni in mice and men

    Allen W Cheever;Karl F Hoffmann;Thomas A Wynn

  • Anti-schistosomal Intervention Targets Identified by Lifecycle Transcriptomic Analyses

    Jennifer M. Fitzpatrick;Emily Peak;Samirah Perally;Iain Wyllie Chalmers

  • Disease fingerprinting with cDNA microarrays reveals distinct gene expression profiles in lethal type-1 and type-2 cytokine-mediated inflammatory reactions

    Karl F. Hoffmann;Thomas C. McCarty;David H. Segal;Monica Chiaramonte

  • An oligonucleotide microarray for transcriptome analysis of Schistosoma mansoni and its application/use to investigate gender-associated gene expression

    Jennifer M. Fitzpatrick;David A. Johnston;Gary W. Williams;Debbie J. Williams

  • Glycomic Analysis of Life Stages of the Human Parasite Schistosoma mansoni Reveals Developmental Expression Profiles of Functional and Antigenic Glycan Motifs

    Cornelis H. Smit;Angela van Diepen;D. Linh Nguyen;Manfred Wuhrer

  • Development and Validation of a Quantitative, High-Throughput, Fluorescent-Based Bioassay to Detect Schistosoma Viability

    Emily Peak;Iain W. Chalmers;Karl F. Hoffmann

  • Schistosome egg production is dependent upon the activities of two developmentally regulated tyrosinases

    Jennifer M. Fitzpatrick;Yuriko Hirai;Hirohisa Hirai;Karl F. Hoffmann

  • Glycomics-driven discoveries in schistosome research

    Cornelis H. Hokke;André M. Deelder;Karl F. Hoffmann;Manfred Wuhrer

  • Molecular characterization of omega-1: a hepatotoxic ribonuclease from Schistosoma mansoni eggs.

    Colin M. Fitzsimmons;Gabriele Schramm;Frances M. Jones;Iain W. Chalmers

  • Transcription of the Trypanosoma brucei spliced leader RNA gene is dependent only on the presence of upstream regulatory elements.

    Arthur Günzl;Elisabetta Ullu;Marion Dörner;Stenio P Fragoso

  • IFN-gamma, IL-12, and TNF-alpha are required to maintain reduced liver pathology in mice vaccinated with Schistosoma mansoni eggs and IL-12.

    Karl F. Hoffmann;Pat Caspar;Allen W. Cheever;Thomas A. Wynn

  • Biomphalaria glabrata transcriptome: cDNA microarray profiling identifies resistant- and susceptible-specific gene expression in haemocytes from snail strains exposed to Schistosoma mansoni

    Anne E Lockyer;Jenny Spinks;Richard A Kane;Karl F Hoffmann;Karl F Hoffmann

Frequent Co-Authors

Cornelis H. Hokke
Cornelis H. Hokke Leiden University Medical Center
David W. Dunne
David W. Dunne University of Cambridge
Thomas A. Wynn
Thomas A. Wynn Pfizer (United States)
Matthew Berriman
Matthew Berriman University of Glasgow
Allen W. Cheever
Allen W. Cheever National Institutes of Health
Paul J. Brindley
Paul J. Brindley George Washington University
Timothy P. Yoshino
Timothy P. Yoshino University of Wisconsin–Madison
Maria Yazdanbakhsh
Maria Yazdanbakhsh Leiden University Medical Center
Manfred Wuhrer
Manfred Wuhrer Leiden University Medical Center
Birgitte J. Vennervald
Birgitte J. Vennervald University of Copenhagen

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Best Scientists Citing Karl F. Hoffmann

Donald P. McManus

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Pfizer (United States)

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Publications: 53

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Geoffrey N. Gobert

Geoffrey N. Gobert

Queen's University Belfast

Publications: 43

Cornelis H. Hokke

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Leiden University Medical Center

Publications: 37

Matthew Berriman

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Publications: 35

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National Institute of Allergy and Infectious Diseases

Publications: 32

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Publications: 32

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Johns Hopkins University

Publications: 30

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Publications: 29

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