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6055
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Overview

Johji Yamahara is affiliated with Kyoto Pharmaceutical University in Japan. Their research primarily focuses on the interconnected areas of medicine, biochemistry, genetics, and molecular biology. Within these broader fields, they have contributed notably to subfields such as molecular biology, epidemiology, endocrinology, diabetes and metabolism, biochemistry, and pharmacology.

Their work covers a range of topics including:

  • Diet, metabolism, and disease
  • Liver disease diagnosis and treatment
  • Metabolism, diabetes, and cancer
  • Medicinal plants and bioactive compounds
  • Natural product bioactivities and synthesis
  • Antioxidant activity and oxidative stress
  • Retinoids in leukemia and cellular processes

Yamahara has published several papers addressing these themes. Selected recent publications include:

  • Apple pomace and rosemary extract ameliorates hepatic steatosis in fructose-fed rats: Association with enhancing fatty acid oxidation and suppressing inflammation, 2020, Experimental and Therapeutic Medicine
  • Rhodiola crenulata root extract ameliorates fructose-induced hepatic steatosis in rats: Association with activating autophagy, 2020, Biomedicine & Pharmacotherapy
  • Ursolic acid ameliorates adipose tissue insulin resistance in aged rats via activating the Akt-glucose transporter 4 signaling pathway and inhibiting inflammation, 2021, Experimental and Therapeutic Medicine
  • Oleanolic Acid Inhibits SCD1 Gene Expression to Ameliorate Fructose-Induced Hepatosteatosis through SREBP1c-Dependent and -Independent Mechanisms, 2023, Molecular Nutrition & Food Research
  • [6-Gingerol ameliorates adipose tissue insulin resistance in aging rats]., 2022, PubMed

Their frequent publication venues include:

  • Experimental and Therapeutic Medicine
  • Biomedicine & Pharmacotherapy
  • Molecular Nutrition & Food Research
  • PubMed

Collaborations have involved several coauthors with whom Yamahara has published multiple times. These coauthors are:

  • Chunlin Yuan
  • Ling Yao
  • Jianwei Wang
  • Tongzhuang Wang
  • Ying Lai

Best Publications

  • Salacinol, potent antidiabetic principle with unique thiosugar sulfonium sulfate structure from the ayurvedic traditional medicine Salacia reticulata in Sri Lanka and India

    Masayuki Yoshikawa;Toshiyuki Murakami;Hiromi Shimada;Hisashi Matsuda

  • Anti-diabetic action of Punica granatum flower extract: activation of PPAR-gamma and identification of an active component.

    Tom H W Huang;Gang Peng;Bhavani P Kota;George Q Li

  • Punica granatum flower extract, a potent alpha-glucosidase inhibitor, improves postprandial hyperglycemia in Zucker diabetic fatty rats.

    Yuhao Li;Suping Wen;Bhavani Prasad Kota;Gang Peng

  • The inhibitory effects of mangiferin, a naturally occurring glucosylxanthone, in bowel carcinogenesis of male F344 rats.

    Naoki Yoshimi;Kengo Matsunaga;Masaki Katayama;Yasuhiro Yamada

  • Gastrointestinal motility enhancing effect of ginger and its active constituents.

    J. Yamahara;Qirong Huang;Yuhao Li;Lin Xu

  • Inhibitory effects of plumbagin and juglone on azoxymethane-induced intestinal carcinogenesis in rats

    Shigeyuki Sugie;Kiyohisa Okamoto;K.M.Wahidur Rahman;Takuji Tanaka

  • Medicinal Foodstuffs. IV. Fenugreek Seed. (1) : Structures of Trigoneosides Ia, Ib, IIa, IIb, IIIa, and IIIb, New Furostanol Saponins from the Seeds of Indian Trigonella foenum-graecum L.

    Masayuki Yoshikawa;Toshiyuki Murakami;Hajime Komatsu;Nobutoshi Murakami

  • Pomegranate flower improves cardiac lipid metabolism in a diabetic rat model: role of lowering circulating lipids.

    Tom Hsun-Wei Huang;Gang Peng;Bhavani Prasad Kota;George Qian Li

  • Antidiabetic Principles of Natural Medicines. IV. Aldose Reductase and α-Glucosidase Inhibitors from the Roots of Salacia oblonga WALL. (Celastraceae) : Structure of a New Friedelane-Type Triterpene, Kotalagenin 16-Acetate

    Hisashi Matsuda;Toshiyuki Murakami;Kenichi Yashiro;Johji Yamahara

  • Medicinal Foodstuffs. V. Moroheiya. (1) : Absolute Stereostructures of Corchoionosides A, B, and C, Histamine Release Inhibitors from the Leaves of Vietnamese Corchorus olitorius L. (Tiliaceae)

    Masayuki Yoshikawa;Hiromi Shimada;Masami Saka;Satoshi Yoshizumi

  • Antidiabetic Principles of Natural Medicines. II. Aldose Reductase and α-Glucosidase Inhibitors from Brazilian Natural Medicine, the Leaves of Myrcia multiflora DC. (Myrtacae) : Structures of Myrciacitrins I and II and Myrciaphenones A and B

    Masayuki Yoshikawa;Hiromi Shimada;Norihisa Nishida;Yuhao Li

  • THE ANTI-ULCER EFFECT IN RATS OF GINGER CONSTITUENTS

    J Yamahara;M Mochizuki;H Q Rong;H Matsuda

  • Pomegranate flower extract diminishes cardiac fibrosis in Zucker diabetic fatty rats: modulation of cardiac endothelin-1 and nuclear factor-kappaB pathways.

    Tom H W Huang;Qinglin Yang;Masaki Harada;George Q Li

  • Pomegranate flower: a unique traditional antidiabetic medicine with dual PPAR‐α/‐γ activator properties

    Yuhao Li;Yanfei Qi;Tom Hsun-Wei Huang;Johji Yamahara

  • Effects of escins Ia, Ib, IIa, and IIb from horse chestnut, the seeds of Aesculus hippocastanum L., on acute inflammation in animals

    Hisashi Matsuda;Yuhao Li;Toshiyuki Murakami;Kiyofumi Ninomiya

  • Antidiabetic Principles of Natural Medicines. III. Structure-Related Inhibitory Activity and Action Mode of Oleanolic Acid Glycosides on Hypoglycemic Activity

    Hisashi Matsuda;Yuhao Li;Toshiyuki Murakami;Narumi Matsumura

  • Salacia oblonga root improves postprandial hyperlipidemia and hepatic steatosis in Zucker diabetic fatty rats: activation of PPAR-alpha.

    Tom Hsun-Wei Huang;Gang Peng;George Qian Li;Johji Yamahara

  • A 35-day gavage safety assessment of ginger in rats.

    Xianglu Rong;Gang Peng;Takuya Suzuki;Qinglin Yang

  • Stomachic principles in ginger. III: An anti-ulcer principle, 6-gingesulfonic acid, and three monoacyldigalactosylglycerols, gingerglycolipids A, B, and C, from zingiberis rhizoma originating in Taiwan

    Masayuki Yoshikawa;Shoko Yamaguchi;Kumiko Kunimi;Hisashi Matsuda

  • Bioactive saponins and glycosides. VIII. Notoginseng (1): New dammarane-type triterpene oligoglycosides, notoginsenosides-A, -B, -C, and -D, from the dried root of Panax notoginseng (BURK.) F. H. Chen

    Masayuki Yoshikawa;Toshiyuki Murakami;Takahiro Ueno;Kenichi Yashiro

Frequent Co-Authors

Masayuki Yoshikawa
Masayuki Yoshikawa Kyoto Pharmaceutical University
Hisashi Matsuda
Hisashi Matsuda Kyoto Pharmaceutical University
Toshiyuki Murakami
Toshiyuki Murakami Kyoto Pharmaceutical University
Hiroshi Matsuda
Hiroshi Matsuda Tokyo University of Agriculture and Technology
Basil D. Roufogalis
Basil D. Roufogalis University of Sydney
Takuji Tanaka
Takuji Tanaka Gifu University
Isao Kitagawa
Isao Kitagawa Osaka University
Hideki Mori
Hideki Mori Gifu University
Robert T. Batey
Robert T. Batey University of Colorado Boulder
Osamu Tanaka
Osamu Tanaka Maruzen Pharmaceuticals Co. Ltd.

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