His primary areas of investigation include Genetics, Internal medicine, Type 2 diabetes, Endocrinology and Single-nucleotide polymorphism. His work in Internal medicine covers topics such as Genotype which are related to areas like Allele, Coding region and Missense mutation. His study looks at the relationship between Type 2 diabetes and fields such as TCF7L2, as well as how they intersect with chemical problems.
His Endocrinology course of study focuses on Risk factor and SH2B1. His Single-nucleotide polymorphism research is multidisciplinary, incorporating perspectives in Polymorphism, Allele frequency and Human genetics. His studies in Obesity integrate themes in fields like Body mass index, FTO gene and Birth weight.
The scientist’s investigation covers issues in Internal medicine, Diabetes mellitus, Endocrinology, Genetics and Type 2 diabetes. His Internal medicine study frequently draws connections to other fields, such as Genotype. While the research belongs to areas of Diabetes mellitus, Graham A. Hitman spends his time largely on the problem of Immunology, intersecting his research to questions surrounding Coeliac disease.
His Endocrinology research incorporates themes from Receptor and Candidate gene. Locus, Allele, Haplotype, Single-nucleotide polymorphism and Gene are subfields of Genetics in which his conducts study. His Type 2 diabetes research incorporates elements of Odds ratio, Case-control study, TCF7L2, Genetic association and Insulin resistance.
Graham A. Hitman focuses on Internal medicine, Pregnancy, Diabetes mellitus, Type 2 diabetes and Endocrinology. Graham A. Hitman has researched Internal medicine in several fields, including Single-nucleotide polymorphism and Bioinformatics. He combines subjects such as Psychological intervention, Obesity and Pediatrics with his study of Pregnancy.
His Diabetes mellitus study combines topics in areas such as Clinical trial and Vitamin B12. Graham A. Hitman has included themes like Human physiology, Metabolic syndrome and Insulin resistance in his Type 2 diabetes study. His biological study spans a wide range of topics, including Receptor, Downregulation and upregulation, Randomized controlled trial and DNA methylation.
Graham A. Hitman mostly deals with Internal medicine, Endocrinology, Type 2 diabetes, Pregnancy and Diabetes mellitus. His studies deal with areas such as Transcription factor and Programmed cell death as well as Internal medicine. His Endocrinology study combines topics from a wide range of disciplines, such as Microarray analysis techniques, Downregulation and upregulation, Gene knockdown and DNA methylation.
The various areas that Graham A. Hitman examines in his Type 2 diabetes study include Human physiology, Overweight and Metabolic syndrome. Graham A. Hitman has researched Diabetes mellitus in several fields, including Ophthalmology and Visual acuity. His Cholesterol research includes themes of Gastroenterology, Genome-wide association study, Diabetic angiopathy and C-reactive protein.
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Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
Paul R. Burton;David G. Clayton;Lon R. Cardon;Nick Craddock.
Nature (2007)
A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity
Timothy M. Frayling;Nicholas J. Timpson;Michael N. Weedon;Eleftheria Zeggini;Eleftheria Zeggini;Eleftheria Zeggini.
Science (2007)
Primary prevention of cardiovascular disease with atorvastatin in type 2 diabetes in the Collaborative Atorvastatin Diabetes Study (CARDS): multicentre randomised placebo-controlled trial
Helen M Colhoun;D John Betteridge;Paul N Durrington;Graham A Hitman.
The Lancet (2004)
Replication of Genome-Wide Association Signals in UK Samples Reveals Risk Loci for Type 2 Diabetes
Eleftheria Zeggini;Michael N. Weedon;Cecilia M. Lindgren;Timothy M. Frayling.
Science (2007)
Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes
E Zeggini;L J Scott;R Saxena;B F Voight.
Nature Genetics (2008)
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis
Benjamin F. Voight;Benjamin F. Voight;Laura J. Scott;Valgerdur Steinthorsdottir;Andrew P. Morris.
Nature Genetics (2010)
A genome-wide association search for type 2 diabetes genes in African Americans.
N D Palmer;C W McDonough;P J Hicks;B H Roh.
PLOS ONE (2012)
GERMLINE MUTATIONS IN THE EXTRACELLULAR DOMAINS OF THE 55 KDA TNF RECEPTOR, TNFR1, DEFINE A FAMILY OF DOMINANTLY INHERITED AUTOINFLAMMATORY SYNDROMES
Michael F McDermott;Ivona Aksentijevich;Jérôme Galon;Elizabeth M McDermott.
Cell (1999)
Genome-wide association study identifies eight loci associated with blood pressure
Christopher Newton-Cheh;Christopher Newton-Cheh;Toby Johnson;Toby Johnson;Vesela Gateva;Martin D. Tobin.
Nature Genetics (2009)
Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants
Paul R Burton;David G Clayton;Lon R Cardon;Nick Craddock.
Nature Genetics (2007)
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