The scientist’s investigation covers issues in Apoptosis, Biochemistry, Cell biology, Internal medicine and Programmed cell death. He combines subjects such as Tumor necrosis factor alpha, Lipid raft and Resveratrol with his study of Apoptosis. His studies deal with areas such as THP1 cell line, Oxysterol, Endothelium and Vitamin E as well as Cell biology.
As part of his studies on Internal medicine, Philippe Gambert frequently links adjacent subjects like Endocrinology. His Programmed cell death research is multidisciplinary, relying on both Mitochondrion, Glutathione, Superoxide and Pharmacology. His work deals with themes such as Cholesteryl ester, Very low-density lipoprotein, Lipoprotein and Chromatography, which intersect with Apolipoprotein B.
His scientific interests lie mostly in Internal medicine, Endocrinology, Apolipoprotein B, Lipoprotein and Cholesterol. Philippe Gambert works mostly in the field of Internal medicine, limiting it down to topics relating to Type 1 diabetes and, in certain cases, Autoimmune disease. His Apolipoprotein B study combines topics from a wide range of disciplines, such as Enzyme, Low-density lipoprotein, High-density lipoprotein and Metabolism.
As a member of one scientific family, Philippe Gambert mostly works in the field of Lipoprotein, focusing on Chromatography and, on occasion, Gel electrophoresis. His Cholesterol research incorporates elements of Endothelium and Vascular disease. Cholesterylester transfer protein is a subfield of Biochemistry that he tackles.
Philippe Gambert mostly deals with Internal medicine, Endocrinology, Cholesterol, Apolipoprotein B and Myocardial infarction. Internal medicine is closely attributed to Type 1 diabetes in his research. His work on Statin expands to the thematically related Endocrinology.
His work on Triglyceride, Very low-density lipoprotein and Apolipoprotein C as part of general Cholesterol study is frequently connected to Wild type, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them. Philippe Gambert has included themes like High-density lipoprotein and Metabolism in his Apolipoprotein B study. His research in Myocardial infarction intersects with topics in Natriuretic peptide, Cancer research, Surgery and Renal function.
Philippe Gambert mainly focuses on Internal medicine, Endocrinology, Biochemistry, Cholesterol and Apolipoprotein B. His work on Myocardial infarction, Triglyceride, Vasodilation and Agonist as part of general Internal medicine research is frequently linked to Retinoic acid receptor alpha, bridging the gap between disciplines. His Triglyceride research is multidisciplinary, incorporating perspectives in Abdominal obesity, Obese subjects and High-density lipoprotein.
His work in the fields of Biochemistry, such as Beta oxidation, Polyunsaturated fatty acid, Peroxisome and Adrenoleukodystrophy, overlaps with other areas such as Wild type. His Cholesterol and Lipoprotein and Cholesterylester transfer protein investigations all form part of his Cholesterol research activities. His Lipoprotein study integrates concerns from other disciplines, such as Adiponectin, Insulin resistance and Metabolic syndrome.
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Cisplatin-Induced CD95 Redistribution into Membrane Lipid Rafts of HT29 Human Colon Cancer Cells
Sandrine Lacour;Arlette Hammann;Solène Grazide;Dominique Lagadic-Gossmann.
Cancer Research (2004)
Resveratrol-induced Apoptosis Is Associated with Fas Redistribution in the Rafts and the Formation of a Death-inducing Signaling Complex in Colon Cancer Cells
Dominique Delmas;Cédric Rébé;Sandrine Lacour;Rodolphe Filomenko.
Journal of Biological Chemistry (2003)
Glutathione is implied in the control of 7-ketocholesterol-induced apoptosis, which is associated with radical oxygen species production
Gerard Lizard;Serge Gueldry;Olivier Sordet;Serge Monier.
The FASEB Journal (1998)
Characterization and Comparison of the Mode of Cell Death, Apoptosis Versus Necrosis, Induced by 7β-Hydroxycholesterol and 7-Ketocholesterol in the Cells of the Vascular Wall
Gérard Lizard;Serge Monier;Catherine Cordelet;Laurence Gesquière.
Arteriosclerosis, Thrombosis, and Vascular Biology (1999)
Redistribution of CD95, DR4 and DR5 in rafts accounts for the synergistic toxicity of resveratrol and death receptor ligands in colon carcinoma cells.
Dominique Delmas;Cédric Rébé;Olivier Micheau;Anne Athias.
Oncogene (2004)
Involvement of a calcium-dependent dephosphorylation of BAD associated with the localization of Trpc-1 within lipid rafts in 7-ketocholesterol-induced THP-1 cell apoptosis
A Berthier;S Lemaire-Ewing;C Prunet;S Monier.
Cell Death & Differentiation (2004)
Comparison of the cytotoxic, pro-oxidant and pro-inflammatory characteristics of different oxysterols.
S Lemaire-Ewing;C Prunet;T Montange;A Vejux.
Cell Biology and Toxicology (2005)
Impairment with various antioxidants of the loss of mitochondrial transmembrane potential and of the cytosolic release of cytochrome c occuring during 7-ketocholesterol-induced apoptosis.
Gérard Lizard;Carole Miguet;Ginette Besséde;Serge Monier.
Free Radical Biology and Medicine (2000)
Induction of apoptosis in endothelial cells treated with cholesterol oxides.
G Lizard;V Deckert;L Dubrez;M Moisant.
American Journal of Pathology (1996)
Adiponectin Is an Important Determinant of ApoA-I Catabolism
Bruno Vergès;Jean Michel Petit;Laurence Duvillard;Guillaume Dautin.
Arteriosclerosis, Thrombosis, and Vascular Biology (2006)
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