D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 78 Citations 28,083 154 World Ranking 1935 National Ranking 1089

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • DNA

His main research concerns Molecular biology, Single-nucleotide polymorphism, Genetics, Allele and Biochemistry. His Molecular biology research incorporates themes from Cell culture, Transfection, Messenger RNA and Hepatocyte. Erin G. Schuetz combines subjects such as P-glycoprotein, CYP3A, Phenobarbital and In vivo with his study of Cell culture.

His work focuses on many connections between CYP3A and other disciplines, such as Pharmacology, that overlap with his field of interest in CYP3A4, Gastroenterology, CYP3A5 and Furanocoumarin. His research in Single-nucleotide polymorphism intersects with topics in Alternative splicing, Exon, Gene expression and Haplotype. Erin G. Schuetz interconnects Pharmacogenetics and Genetic variation in the investigation of issues within Allele.

His most cited work include:

  • Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression. (1770 citations)
  • Stat5a and Stat5b Proteins Have Essential and Nonessential, or Redundant, Roles in Cytokine Responses (1185 citations)
  • Identification of functionally variant MDR1 alleles among European Americans and African Americans (902 citations)

What are the main themes of his work throughout his whole career to date?

His primary scientific interests are in Molecular biology, Pharmacology, Internal medicine, Endocrinology and Genetics. The various areas that he examines in his Molecular biology study include Cell culture, Gene expression, Hepatocyte, Messenger RNA and Cytochrome P450. His study in Pharmacology is interdisciplinary in nature, drawing from both CYP3A4, P-glycoprotein, CYP3A and In vivo.

His Internal medicine research is multidisciplinary, incorporating elements of Gastroenterology and Genotype. His study in Genetics concentrates on Single-nucleotide polymorphism, Allele, Gene, Genetic variation and Pharmacogenetics. His Single-nucleotide polymorphism course of study focuses on Exon and Intron.

He most often published in these fields:

  • Molecular biology (35.24%)
  • Pharmacology (34.76%)
  • Internal medicine (26.67%)

What were the highlights of his more recent work (between 2009-2021)?

  • Genetics (18.57%)
  • Endocrinology (19.05%)
  • Internal medicine (26.67%)

In recent papers he was focusing on the following fields of study:

Erin G. Schuetz mainly investigates Genetics, Endocrinology, Internal medicine, Pharmacology and Pregnane X receptor. His study in Allele, Genetic variation, Genotype, Gene and Phenotype is done as part of Genetics. His study on Haplotype is often connected to Bupropion as part of broader study in Genotype.

His Pharmacology study combines topics in areas such as CYP3A4, Cell culture and P-glycoprotein. His Pregnane X receptor research includes elements of Metabolite, Molecular biology, Nuclear receptor coactivator 2 and Constitutive androstane receptor. As a part of the same scientific study, Erin G. Schuetz usually deals with the Molecular biology, concentrating on Regulation of gene expression and frequently concerns with Gene knockdown, Gene expression and Luciferase.

Between 2009 and 2021, his most popular works were:

  • Systematic genetic and genomic analysis of cytochrome P450 enzyme activities in human liver (198 citations)
  • Identification, Replication, and Functional Fine-Mapping of Expression Quantitative Trait Loci in Primary Human Liver Tissue (185 citations)
  • Genetic Predictors of Interindividual Variability in Hepatic CYP3A4 Expression (88 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • DNA

Erin G. Schuetz mostly deals with Pharmacology, Genetics, Pregnane X receptor, CYP3A4 and Constitutive androstane receptor. His Pharmacology research is multidisciplinary, incorporating perspectives in Metabolite, P-glycoprotein, Xenobiotic and Cytochrome P450. Single-nucleotide polymorphism, Genome-wide association study, Gene, Genetic variation and CYP3A are among the areas of Genetics where Erin G. Schuetz concentrates his study.

His Genetic variation study combines topics from a wide range of disciplines, such as Allele, Polymorphism, Genotype, Transactivation and Corepressor. The study of Pregnane X receptor is intertwined with the study of Molecular biology in a number of ways. The study incorporates disciplines such as Vitamin D and neurology, Pharmacokinetics and In vivo in addition to CYP3A4.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression.

Peter Kuehl;Jiong Zhang;Yvonne Lin;Jatinder Lamba.
Nature Genetics (2001)

2423 Citations

Stat5a and Stat5b Proteins Have Essential and Nonessential, or Redundant, Roles in Cytokine Responses

Stephan Teglund;Catriona McKay;Erin Schuetz;Jan M van Deursen.
Cell (1998)

1452 Citations

Identification of functionally variant MDR1 alleles among European Americans and African Americans

Richard B. Kim;Richard B. Kim;Brenda F. Leake;Brenda F. Leake;Edna F. Choo;Edna F. Choo;George K. Dresser;George K. Dresser.
Clinical Pharmacology & Therapeutics (2001)

1238 Citations

Genetic contribution to variable human CYP3A-mediated metabolism

Jatinder K Lamba;Yvonne S Lin;Erin G Schuetz;Kenneth E Thummel.
Advanced Drug Delivery Reviews (2002)

1100 Citations

Mapping the Genetic Architecture of Gene Expression in Human Liver

Eric E. Schadt;Cliona Molony;Eugene Chudin;Ke-Ke Hao.
PLOS Biology (2008)

1095 Citations

Modulators and substrates of P-glycoprotein and cytochrome P4503A coordinately up-regulate these proteins in human colon carcinoma cells.

E G Schuetz;W T Beck;J D Schuetz.
Molecular Pharmacology (1996)

638 Citations

Identification of glucocorticoid-inducible cytochromes P-450 in the intestinal mucosa of rats and man.

P B Watkins;S A Wrighton;E G Schuetz;D T Molowa.
Journal of Clinical Investigation (1987)

584 Citations

Regulation of gene expression in adult rat hepatocytes cultured on a basement membrane matrix

Erin G. Schuetz;Donna Li;Curtis J. Omiecinski;Ursula Muller‐Eberhard.
Journal of Cellular Physiology (1988)

543 Citations

Co-regulation of CYP3A4 and CYP3A5 and contribution to hepatic and intestinal midazolam metabolism.

Yvonne S. Lin;Amy L. S. Dowling;Sean D. Quigley;Federico M. Farin.
Molecular Pharmacology (2002)

518 Citations

The orphan nuclear receptor HNF4α determines PXR- and CAR-mediated xenobiotic induction of CYP3A4

Rommel G Tirona;Wooin Lee;Brenda F Leake;Lu-Bin Lan.
Nature Medicine (2003)

511 Citations

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