His main research concerns Molecular biology, Single-nucleotide polymorphism, Genetics, Allele and Biochemistry. His Molecular biology research incorporates themes from Cell culture, Transfection, Messenger RNA and Hepatocyte. Erin G. Schuetz combines subjects such as P-glycoprotein, CYP3A, Phenobarbital and In vivo with his study of Cell culture.
His work focuses on many connections between CYP3A and other disciplines, such as Pharmacology, that overlap with his field of interest in CYP3A4, Gastroenterology, CYP3A5 and Furanocoumarin. His research in Single-nucleotide polymorphism intersects with topics in Alternative splicing, Exon, Gene expression and Haplotype. Erin G. Schuetz interconnects Pharmacogenetics and Genetic variation in the investigation of issues within Allele.
His primary scientific interests are in Molecular biology, Pharmacology, Internal medicine, Endocrinology and Genetics. The various areas that he examines in his Molecular biology study include Cell culture, Gene expression, Hepatocyte, Messenger RNA and Cytochrome P450. His study in Pharmacology is interdisciplinary in nature, drawing from both CYP3A4, P-glycoprotein, CYP3A and In vivo.
His Internal medicine research is multidisciplinary, incorporating elements of Gastroenterology and Genotype. His study in Genetics concentrates on Single-nucleotide polymorphism, Allele, Gene, Genetic variation and Pharmacogenetics. His Single-nucleotide polymorphism course of study focuses on Exon and Intron.
Erin G. Schuetz mainly investigates Genetics, Endocrinology, Internal medicine, Pharmacology and Pregnane X receptor. His study in Allele, Genetic variation, Genotype, Gene and Phenotype is done as part of Genetics. His study on Haplotype is often connected to Bupropion as part of broader study in Genotype.
His Pharmacology study combines topics in areas such as CYP3A4, Cell culture and P-glycoprotein. His Pregnane X receptor research includes elements of Metabolite, Molecular biology, Nuclear receptor coactivator 2 and Constitutive androstane receptor. As a part of the same scientific study, Erin G. Schuetz usually deals with the Molecular biology, concentrating on Regulation of gene expression and frequently concerns with Gene knockdown, Gene expression and Luciferase.
Erin G. Schuetz mostly deals with Pharmacology, Genetics, Pregnane X receptor, CYP3A4 and Constitutive androstane receptor. His Pharmacology research is multidisciplinary, incorporating perspectives in Metabolite, P-glycoprotein, Xenobiotic and Cytochrome P450. Single-nucleotide polymorphism, Genome-wide association study, Gene, Genetic variation and CYP3A are among the areas of Genetics where Erin G. Schuetz concentrates his study.
His Genetic variation study combines topics from a wide range of disciplines, such as Allele, Polymorphism, Genotype, Transactivation and Corepressor. The study of Pregnane X receptor is intertwined with the study of Molecular biology in a number of ways. The study incorporates disciplines such as Vitamin D and neurology, Pharmacokinetics and In vivo in addition to CYP3A4.
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Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression.
Peter Kuehl;Jiong Zhang;Yvonne Lin;Jatinder Lamba.
Nature Genetics (2001)
Stat5a and Stat5b Proteins Have Essential and Nonessential, or Redundant, Roles in Cytokine Responses
Stephan Teglund;Catriona McKay;Erin Schuetz;Jan M van Deursen.
Identification of functionally variant MDR1 alleles among European Americans and African Americans
Richard B. Kim;Richard B. Kim;Brenda F. Leake;Brenda F. Leake;Edna F. Choo;Edna F. Choo;George K. Dresser;George K. Dresser.
Clinical Pharmacology & Therapeutics (2001)
Genetic contribution to variable human CYP3A-mediated metabolism
Jatinder K Lamba;Yvonne S Lin;Erin G Schuetz;Kenneth E Thummel.
Advanced Drug Delivery Reviews (2002)
Mapping the Genetic Architecture of Gene Expression in Human Liver
Eric E. Schadt;Cliona Molony;Eugene Chudin;Ke-Ke Hao.
PLOS Biology (2008)
Modulators and substrates of P-glycoprotein and cytochrome P4503A coordinately up-regulate these proteins in human colon carcinoma cells.
E G Schuetz;W T Beck;J D Schuetz.
Molecular Pharmacology (1996)
Identification of glucocorticoid-inducible cytochromes P-450 in the intestinal mucosa of rats and man.
P B Watkins;S A Wrighton;E G Schuetz;D T Molowa.
Journal of Clinical Investigation (1987)
Regulation of gene expression in adult rat hepatocytes cultured on a basement membrane matrix
Erin G. Schuetz;Donna Li;Curtis J. Omiecinski;Ursula Muller‐Eberhard.
Journal of Cellular Physiology (1988)
Co-regulation of CYP3A4 and CYP3A5 and contribution to hepatic and intestinal midazolam metabolism.
Yvonne S. Lin;Amy L. S. Dowling;Sean D. Quigley;Federico M. Farin.
Molecular Pharmacology (2002)
The orphan nuclear receptor HNF4α determines PXR- and CAR-mediated xenobiotic induction of CYP3A4
Rommel G Tirona;Wooin Lee;Brenda F Leake;Lu-Bin Lan.
Nature Medicine (2003)
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