World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
93
Citations
34062
World Ranking
2086
National Ranking
1137

Overview

Erin G. Schuetz is affiliated with St. Jude Children's Research Hospital in the United States. Their research encompasses multiple areas within medicine and biochemistry, genetics, and molecular biology, with notable contributions to molecular biology, genetics, pharmacology, oncology, and public health.

They have contributed to several recent publications, including:

  • Genetic effects on liver chromatin accessibility identify disease regulatory variants, 2021, The American Journal of Human Genetics
  • Metabolomic and transcriptomic analysis reveals endogenous substrates and metabolic adaptation in rats lacking Abcg2 and Abcb1a transporters, 2021, PLoS ONE
  • Role of Vitamins A and D in BCR-ABL Arf−/− Acute Lymphoblastic Leukemia, 2020, Scientific Reports
  • Characterization of CYP3A pharmacogenetic variation in American Indian and Alaska Native communities, targeting CYP3A4*1G allele function, 2021, Clinical and Translational Science
  • Functional characterization of novel rare CYP2A6 variants and potential implications for clinical outcomes, 2021, Clinical and Translational Science

Their frequent coauthors include:

  • Kevin W. Currin
  • Swarooparani Vadlamudi
  • Hannah J. Perrin
  • K. Alaine Broadaway
  • Amy S. Etheridge

Schuetz´s work is often featured in these publication venues:

  • PLoS ONE
  • Clinical and Translational Science
  • Drug Metabolism and Pharmacokinetics
  • The American Journal of Human Genetics
  • Scientific Reports

Main fields of study associated with their research include:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Within these disciplines, subfields that are prominent in their work encompass:

  • Molecular Biology
  • Genetics
  • Pharmacology
  • Oncology
  • Public Health, Environmental and Occupational Health

The primary research topics that Erin G. Schuetz investigates are:

  • Genetic Associations and Epidemiology
  • Epigenetics and DNA Methylation
  • Genomics and Chromatin Dynamics
  • Drug Transport and Resistance Mechanisms
  • Acute Lymphoblastic Leukemia research
  • Pharmacogenetics and Drug Metabolism
  • Metabolism and Genetic Disorders

Best Publications

  • Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression.

    Peter Kuehl;Jiong Zhang;Yvonne Lin;Jatinder Lamba

  • Stat5a and Stat5b Proteins Have Essential and Nonessential, or Redundant, Roles in Cytokine Responses

    Stephan Teglund;Catriona McKay;Erin Schuetz;Jan M van Deursen

  • Identification of functionally variant MDR1 alleles among European Americans and African Americans

    Richard B. Kim;Richard B. Kim;Brenda F. Leake;Brenda F. Leake;Edna F. Choo;Edna F. Choo;George K. Dresser;George K. Dresser

  • Genetic contribution to variable human CYP3A-mediated metabolism

    Jatinder K Lamba;Yvonne S Lin;Erin G Schuetz;Kenneth E Thummel

  • Mapping the Genetic Architecture of Gene Expression in Human Liver

    Eric E. Schadt;Cliona Molony;Eugene Chudin;Ke-Ke Hao

  • Modulators and substrates of P-glycoprotein and cytochrome P4503A coordinately up-regulate these proteins in human colon carcinoma cells.

    E G Schuetz;W T Beck;J D Schuetz

  • Identification of glucocorticoid-inducible cytochromes P-450 in the intestinal mucosa of rats and man.

    P B Watkins;S A Wrighton;E G Schuetz;D T Molowa

  • Regulation of gene expression in adult rat hepatocytes cultured on a basement membrane matrix

    Erin G. Schuetz;Donna Li;Curtis J. Omiecinski;Ursula Muller‐Eberhard

  • Co-regulation of CYP3A4 and CYP3A5 and contribution to hepatic and intestinal midazolam metabolism.

    Yvonne S. Lin;Amy L. S. Dowling;Sean D. Quigley;Federico M. Farin

  • The orphan nuclear receptor HNF4alpha determines PXR- and CAR-mediated xenobiotic induction of CYP3A4.

    Rommel G Tirona;Wooin Lee;Brenda F Leake;Lu-Bin Lan

  • The Xenobiotic Compound 1,4-Bis(2-(3,5-Dichloropyridyloxy))Benzene Is an Agonist Ligand for the Nuclear Receptor CAR

    Iphigenia Tzameli;Pavlos Pissios;Erin G. Schuetz;David D. Moore

  • Identification of an inducible form of cytochrome P-450 in human liver

    P B Watkins;S A Wrighton;P Maurel;E G Schuetz

  • Hepatic CYP2B6 expression: gender and ethnic differences and relationship to CYP2B6 genotype and CAR (constitutive androstane receptor) expression.

    Vishal Lamba;Jatinder Lamba;Kazuto Yasuda;Stephen Strom

  • Disrupted bile acid homeostasis reveals an unexpected interaction among nuclear hormone receptors, transporters, and cytochrome P450.

    Erin G. Schuetz;Stephen Strom;Kazuto Yasuda;Valerie Lecureur

  • Common allelic variants of cytochrome P4503A4 and their prevalence in different populations.

    Jatinder K. Lamba;Yvonne S. Lin;Kenneth Thummel;Ann Daly

  • Transcriptional Control of Intestinal Cytochrome P-4503A by 1α,25-Dihydroxy Vitamin D3

    Kenneth E. Thummel;Cynthia Brimer;Kazuto Yasuda;Jaideep Thottassery

  • The human pregnane X receptor: genomic structure and identification and functional characterization of natural allelic variants.

    Jiong Zhang;Peter Kuehl;Eric D. Green;Jeffery W. Touchman

  • Identification of the cytochrome P-450 induced by macrolide antibiotics in rat liver as the glucocorticoid responsive cytochrome P-450p

    Steven A. Wrighton;Patrick Maurel;Erin G. Schuetz;Paul B. Watkins

  • ENHANCED PROTEOLYSIS OF THIOPURINE S-METHYLTRANSFERASE (TPMT) ENCODED BY MUTANT ALLELES IN HUMANS (TPMT*3A, TPMT*2): MECHANISMS FOR THE GENETIC POLYMORPHISM OF TPMT ACTIVITY

    Hung-Liang Tai;Eugene Y. Krynetski;Erin G. Schuetz;Yuri Yanishevski

  • Interindividual variation in expression of P-glycoprotein in normal human liver and secondary hepatic neoplasms.

    E G Schuetz;K N Furuya;J D Schuetz

Frequent Co-Authors

John D. Schuetz
John D. Schuetz St. Jude Children's Research Hospital
Stephen C. Strom
Stephen C. Strom Karolinska Institute
Kenneth E. Thummel
Kenneth E. Thummel University of Washington
Philip S. Guzelian
Philip S. Guzelian University of Colorado Anschutz Medical Campus
Steven A. Wrighton
Steven A. Wrighton Eli Lilly (United States)
Mary V. Relling
Mary V. Relling St. Jude Children's Research Hospital
Paul B. Watkins
Paul B. Watkins University of North Carolina at Chapel Hill
Richard B. Kim
Richard B. Kim University of Western Ontario
Patrick Maurel
Patrick Maurel University of Montpellier
Sean Ekins
Sean Ekins University of Arizona

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