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Biology and Biochemistry

D-Index
70
Citations
17035
World Ranking
7024
National Ranking
180

Overview

Ron H.N. van Schaik is affiliated with Erasmus University Rotterdam in the Netherlands. Their research primarily spans the field of Medicine, with a focus on subfields such as Oncology, Pharmacology, Molecular Biology, Pediatrics, Perinatology and Child Health, and Cardiology and Cardiovascular Medicine.

Their main topics of study include Pharmacogenetics and Drug Metabolism, Pharmaceutical Studies and Practices, Cancer Therapeutics and Mechanisms, Lung Cancer Treatments and Mutations, Pharmacological Effects and Toxicity Studies, Renal Transplantation Outcomes and Treatments, and Colorectal Cancer Treatments and Studies.

Ron H.N. van Schaik has contributed to several journals frequently, including:

  • European Journal of Human Genetics
  • Clinical Pharmacology & Therapeutics
  • Annals of Oncology
  • Journal of Molecular Diagnostics
  • Clinical Chemistry and Laboratory Medicine (CCLM)

Selected recent papers of Ron H.N. van Schaik include:

  • Personalized Therapy for Mycophenolate: Consensus Report by the International Association of Therapeutic Drug Monitoring and Clinical Toxicology, 2021, Therapeutic Drug Monitoring
  • Recommendations for Clinical CYP2D6 Genotyping Allele Selection, 2021, Journal of Molecular Diagnostics
  • Dutch Pharmacogenetics Working Group (DPWG) guideline for the gene-drug interaction between CYP2D6, CYP3A4 and CYP1A2 and antipsychotics, 2023, European Journal of Human Genetics
  • Dutch Pharmacogenetics Working Group (DPWG) guideline for the gene-drug interaction between CYP2C19 and CYP2D6 and SSRIs, 2021, European Journal of Human Genetics
  • Risperidone plasma concentrations are associated with side effects and effectiveness in children and adolescents with autism spectrum disorder, 2020, British Journal of Clinical Pharmacology

Frequent co-authors collaborating with Ron H.N. van Schaik include:

  • Ron H.J. Mathijssen
  • Henk-Jan Guchelaar
  • Jesse J. Swen
  • Mirjam de With
  • Esther Oomen-de Hoop

Best Publications

  • Screening and prostate cancer mortality: results of the European Randomised Study of Screening for Prostate Cancer (ERSPC) at 13 years of follow-up

    Fritz H Schröder;Jonas Hugosson;Monique J Roobol;Teuvo L J Tammela

  • Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci

    Fredrick R. Schumacher;Ali Amin Al Olama;Sonja I. Berndt;Sara Benlloch

  • Genetic polymorphisms of the CYP3A4, CYP3A5, and MDR‐1 genes and pharmacokinetics of the calcineurin inhibitors cyclosporine and tacrolimus

    Dennis A. Hesselink;Ron H. N. van Schaik;Ilse P. van der Heiden;Marloes van der Werf

  • Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for CYP3A5 Genotype and Tacrolimus Dosing

    K.A. Birdwell;B. Decker;J.M. Barbarino;J.F. Peterson

  • A Multicenter Study of [-2]Pro-Prostate Specific Antigen Combined With Prostate Specific Antigen and Free Prostate Specific Antigen for Prostate Cancer Detection in the 2.0 to 10.0 ng/ml Prostate Specific Antigen Range

    William J. Catalona;Alan W. Partin;Martin G. Sanda;John T. Wei

  • Therapeutic Drug Monitoring of Tacrolimus-Personalized Therapy : Second Consensus Report

    Mercè Brunet;Teun Van Gelder;Anders Åsberg;Vincent Haufroid;Vincent Haufroid

  • CYP3A5 variant allele frequencies in Dutch Caucasians.

    Ron H.N. van Schaik;Ilse P. van der Heiden;John N. van den Anker;John N. van den Anker;John N. van den Anker;Jan Lindemans

  • Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction

    David V. Conti;Burcu F. Darst;Lilit C. Moss;Edward J. Saunders

  • Individualization of Irinotecan Treatment: A Review of Pharmacokinetics, Pharmacodynamics, and Pharmacogenetics

    Femke M. de Man;Andrew K. L. Goey;Ron H. N. van Schaik;Ron H. J. Mathijssen

  • DPYD genotype-guided dose individualisation of fluoropyrimidine therapy in patients with cancer: a prospective safety analysis.

    Linda M. Henricks;Carin A.T.C. Lunenburg;Femke M. de Man;Didier Meulendijks

  • Genetic variation in the multidrug and toxin extrusion 1 transporter protein influences the glucose-lowering effect of metformin in patients with diabetes: a preliminary study.

    Matthijs L. Becker;Loes E. Visser;Ron H.N. van Schaik;Albert Hofman

  • Prostate-Specific Antigen (PSA) Isoform p2PSA in Combination with Total PSA and Free PSA Improves Diagnostic Accuracy in Prostate Cancer Detection

    Flip H. Jansen;Ron H.N. van Schaik;Joep Kurstjens;Wolfgang Horninger

  • The prostate health index selectively identifies clinically significant prostate cancer

    Stacy Loeb;Martin G. Sanda;Dennis L. Broyles;Sanghyuk S. Shin

  • Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6 and Tamoxifen Therapy.

    Matthew P. Goetz;Katrin Sangkuhl;Henk Jan Guchelaar;Matthias Schwab

  • A New Functional CYP3A4 Intron 6 Polymorphism Significantly Affects Tacrolimus Pharmacokinetics in Kidney Transplant Recipients

    Laure Elens;Rachida Bouamar;Dennis A. Hesselink;Vincent Haufroid

  • Interpatient variability in the pharmacokinetics of the HIV non-nucleoside reverse transcriptase inhibitor efavirenz: The effect of gender, race, and CYP2B6 polymorphism

    David Burger;Ilse van der Heiden;Charles la Porte;Marchina van der Ende

  • The Detection of Androgen Receptor Splice Variant 7 in Plasma-derived Exosomal RNA Strongly Predicts Resistance to Hormonal Therapy in Metastatic Prostate Cancer Patients

    Marzia Del Re;Elisa Biasco;Stefania Crucitta;Lisa Derosa

  • The Role of Pharmacogenetics in the Disposition of and Response to Tacrolimus in Solid Organ Transplantation

    Dennis A. Hesselink;Rachida Bouamar;Laure Elens;Ron H. N. Van Schaik

  • Population pharmacokinetics of cyclosporine in kidney and heart transplant recipients and the influence of ethnicity and genetic polymorphisms in the MDR-1, CYP3A4, and CYP3A5 genes

    Dennis A. Hesselink;Teun van Gelder;Ron H. N. van Schaik;Aggie H. M. M. Balk

  • CYP3A4*22: promising newly identified CYP3A4 variant allele for personalizing pharmacotherapy.

    Laure Elens;Teun van Gelder;Dennis A Hesselink;Vincent Haufroid;Vincent Haufroid

Frequent Co-Authors

Teun van Gelder
Teun van Gelder Leiden University Medical Center
Ron H.J. Mathijssen
Ron H.J. Mathijssen Erasmus University Rotterdam
Albert Hofman
Albert Hofman Harvard University
Bruno H. Stricker
Bruno H. Stricker Erasmus University Rotterdam
George P. Patrinos
George P. Patrinos University of Patras
Chris H. Bangma
Chris H. Bangma Erasmus University Rotterdam
David E. Neal
David E. Neal University of Cambridge
Henk-Jan Guchelaar
Henk-Jan Guchelaar Leiden University Medical Center
André G. Uitterlinden
André G. Uitterlinden Erasmus University Rotterdam
Alex Sparreboom
Alex Sparreboom The Ohio State University

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