Pablo Pelegrín

Overview

Best Publications

• Pannexin-1 mediates large pore formation and interleukin-1β release by the ATP-gated P2X7 receptor

  Pablo Pelegrin;Annmarie Surprenant

  1660
  Citations

• The gasdermins, a protein family executing cell death and inflammation

  Petr Broz;Pablo Pelegrín;Feng Shao

  1148
  Citations

• The NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory response.

  Alberto Baroja-Mazo;Fatima Martín-Sánchez;Ana I Gomez;Carlos M Martínez

  913
  Citations

• Hepatocyte pyroptosis and release of inflammasome particles induce stellate cell activation and liver fibrosis

  Susanne Gaul;Susanne Gaul;Aleksandra Leszczynska;Fernando Alegre;Fernando Alegre;Benedikt Kaufmann

  505
  Citations

• P2X7 receptor differentially couples to distinct release pathways for IL-1beta in mouse macrophage.

  Pablo Pelegrin;Consuelo Barroso-Gutierrez;Annmarie Surprenant

  478
  Citations

• Cell Volume Regulation Modulates NLRP3 Inflammasome Activation

  Vincent Compan;Alberto Baroja-Mazo;Gloria López-Castejón;Ana I. Gomez

  443
  Citations

• Pannexin-1 Couples to Maitotoxin- and Nigericin-induced Interleukin-1β Release through a Dye Uptake-independent Pathway

  Pablo Pelegrin;Annmarie Surprenant

  368
  Citations

• MCC950 closes the active conformation of NLRP3 to an inactive state.

  Ana Tapia-Abellán;Diego Angosto-Bazarra;Helios Martínez-Banaclocha;Carlos de Torre-Minguela

  348
  Citations

• Mitochondrial respiratory-chain adaptations in macrophages contribute to antibacterial host defense

  Johan Garaude;Rebeca Acín-Pérez;Sarai Martínez-Cano;Michel Enamorado

  326
  Citations

• Pharmacological Characterization of Pannexin-1 Currents Expressed in Mammalian Cells

  Weihong Ma;Hui Hui;Pablo Pelegrin;Annmarie Surprenant

  319
  Citations

• Dynamics of macrophage polarization reveal new mechanism to inhibit IL‐1β release through pyrophosphates

  Pablo Pelegrin;Annmarie Surprenant

  285
  Citations

• Inflammasome-dependent IL-1β release depends upon membrane permeabilisation.

  F Martín-Sánchez;C Diamond;C Diamond;M Zeitler;A I Gomez

  273
  Citations

• AIM2 and NLRC4 inflammasomes contribute with ASC to acute brain injury independently of NLRP3

  Adam Denes;Graham Coutts;Nikolett Lénárt;Sheena M. Cruickshank

  267
  Citations

• The participation of plasma membrane hemichannels to purinergic signaling

  Alberto Baroja-Mazo;Maria Barberà-Cremades;Pablo Pelegrín

  226
  Citations

• The NLRP3 and Pyrin Inflammasomes: Implications in the Pathophysiology of Autoinflammatory Diseases

  Carlos de Torre-Minguela;Pablo Mesa del Castillo;Pablo Pelegrín

  218
  Citations

• P2X(7) receptor activation enhances SK3 channels- and cystein cathepsin-dependent cancer cells invasiveness.

  B Jelassi;A Chantôme;F Alcaraz-Pérez;A Baroja-Mazo

  217
  Citations

• The P2X7 receptor-pannexin connection to dye uptake and IL-1β release

  Pablo Pelegrin;Annmarie Surprenant

  197
  Citations

• Molecular cloning and expression analysis of tumor necrosis factor α from a marine fish reveal its constitutive expression and ubiquitous nature

  Jesús García-Castillo;Pablo Pelegrín;Victoriano Mulero;José Meseguer

  190
  Citations

• P2X7 receptor induces mitochondrial failure in monocytes and compromises NLRP3 inflammasome activation during sepsis

  Juan José Martínez-García;Helios Martínez-Banaclocha;Diego Angosto-Bazarra;Carlos de Torre-Minguela

  188
  Citations

• Phylogeny of cytokines: molecular cloning and expression analysis of sea bass Dicentrarchus labrax interleukin-1β

  Giuseppe Scapigliati;F Buonocore;Steven Bird;Jun Zou

  180
  Citations