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Biology and Biochemistry

D-Index
75
Citations
20621
World Ranking
5301
National Ranking
195

Overview

Dale W. Laird is affiliated with the University of Western Ontario in Canada. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, with substantial contributions to Medicine as well. The main subfields of their work include Molecular Biology, Genetics, Surgery, Neurology, and Sensory Systems.

The primary topics in their research focus on connexins and lens biology, which encompasses the majority of their publications. Additional areas include studies on Yersinia bacterium, plague, ectoparasites, nicotinic acetylcholine receptors, heat shock proteins, glioma diagnosis and treatment, RNA regulation and disease, and ion channels and receptors.

Recent papers authored or co-authored by Dale W. Laird include:

  • "Single-cell dynamics of pannexin-1-facilitated programmed ATP loss during apoptosis," 2020, published in eLife
  • "Diversity in connexin biology," 2023, published in Journal of Biological Chemistry
  • "Cellular mechanisms of connexin-based inherited diseases," 2021, published in Trends in Cell Biology
  • "Pannexin biology and emerging linkages to cancer," 2021, published in Trends in Cancer
  • "Recent advances in connexin gap junction biology," 2022, published in Faculty Reviews

The scientist has frequently collaborated with several co-authors including Sergiu A. Lucaciu, Silvia Peñuela, Kevin Barr, Emal Lesha, and Stephanie E. Leighton. These collaborative efforts reflect recurring research themes and co-authored publications.

Dale W. Laird's work has appeared in a range of venues, with notable frequent publications in the Journal of Neuro-Oncology, Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature, UNC Libraries, Frontiers in Cell and Developmental Biology, and Journal of Biological Chemistry. These venues suggest a focus on biomedical research and molecular biology.

Best Publications

  • Pannexin 1 channels mediate ‘find-me’ signal release and membrane permeability during apoptosis

    Faraaz B. Chekeni;Michael R. Elliott;Michael R. Elliott;Joanna K. Sandilos;Scott F. Walk;Scott F. Walk

  • Multicolor and Electron Microscopic Imaging of Connexin Trafficking

    Guido Gaietta;Thomas J. Deerinck;Stephen R. Adams;James Bouwer

  • Life cycle of connexins in health and disease

    Dale W. Laird

  • Turnover and phosphorylation dynamics of connexin43 gap junction protein in cultured cardiac myocytes.

    D W Laird;K L Puranam;J P Revel

  • Pannexin 1 and pannexin 3 are glycoproteins that exhibit many distinct characteristics from the connexin family of gap junction proteins

    Silvia Penuela;Ruchi Bhalla;Xiang-Qun Gong;Kyle N. Cowan

  • Sex-specific exons control DNA methyltransferase in mammalian germ cells

    Carmen Mertineit;Jeffrey A. Yoder;Teruko Taketo;Dale W. Laird

  • Inhibition of gap junction and adherens junction assembly by connexin and A-CAM antibodies.

    Rita A. Meyer;Dale W. Laird;Jean Paul Revel;Ross G Johnson

  • The biochemistry and function of pannexin channels.

    Silvia Penuela;Ruchi Gehi;Dale W. Laird

  • Implications and challenges of connexin connections to cancer

    Christian C. Naus;Dale W. Laird

  • Pannexin channels are not gap junction hemichannels

    Gina E. Sosinsky;Daniela Boassa;Rolf Dermietzel;Heather S. Duffy

  • Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: The challenge ahead

    William H Goodson;Leroy Lowe;David O Carpenter;Michael Gilbertson

  • Gap junctions and cancer: communicating for 50 years

    Trond Aasen;Marc Mesnil;Christian C. Naus;Paul D. Lampe

  • Clustering of connexin 43-enhanced green fluorescent protein gap junction channels and functional coupling in living cells.

    Feliksas F. Bukauskas;Karen Jordan;Angele Bukauskiene;Michael V. L. Bennett

  • Connexin phosphorylation as a regulatory event linked to gap junction internalization and degradation.

    Dale W. Laird

  • Migration of Coordinated Cell Clusters in Mesenchymal and Epithelial Cancer Explants in Vitro

    Peter Friedl;Peter B. Noble;Paul A. Walton;Dale W. Laird

  • Gap junction turnover, intracellular trafficking, and phosphorylation of connexin43 in brefeldin A-treated rat mammary tumor cells.

    Dale W. Laird;Muriell Castillo;Lidia Kasprzak

  • The gap junction proteome and its relationship to disease

    Dale W. Laird

  • Deficiency of Connexin43 Gap Junctions Is an Independent Marker for Breast Tumors

    Dale W. Laird;Paulina Fistouris;Gerald Batist;Lesley Alpert

  • Retroviral delivery of connexin genes to human breast tumor cells inhibits in vivo tumor growth by a mechanism that is independent of significant gap junctional intercellular communication.

    Hong Qin;Qing Shao;Heather Curtis;Jacques Galipeau

  • Connexins Act as Tumor Suppressors in Three-dimensional Mammary Cell Organoids by Regulating Differentiation and Angiogenesis

    Elizabeth McLachlan;Qing Shao;Hong-ling Wang;Stephanie Langlois

Frequent Co-Authors

Christian C. Naus
Christian C. Naus University of British Columbia
Paul D. Lampe
Paul D. Lampe Fred Hutchinson Cancer Research Center
Moulay A. Alaoui-Jamali
Moulay A. Alaoui-Jamali McGill University
Gerald M. Kidder
Gerald M. Kidder University of Western Ontario
Brant E. Isakson
Brant E. Isakson University of Virginia
Frank Beier
Frank Beier University of Western Ontario
Brian L. Allman
Brian L. Allman University of Western Ontario
Kodi S. Ravichandran
Kodi S. Ravichandran University of Virginia
Hannah Monyer
Hannah Monyer German Cancer Research Center
Fahd Al-Mulla
Fahd Al-Mulla Kuwait University

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