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Robert G. Gourdie

Robert G. Gourdie

D-Index & Metrics

Biology and Biochemistry

D-Index
68
Citations
15381
World Ranking
7850
National Ranking
3567

Overview

Robert G. Gourdie is affiliated with Virginia Tech in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology with 68 publications, and Medicine with 59 publications. Key subfields of study include Molecular Biology, Cardiology and Cardiovascular Medicine, Biomedical Engineering, Cellular and Molecular Neuroscience, and Cancer Research.

The scientist's work covers a range of topics, notably:

  • Cardiac electrophysiology and arrhythmias
  • Connexins and lens biology
  • Ion channel regulation and function
  • Extracellular vesicles in disease
  • Cardiovascular effects of exercise
  • RNA interference and gene delivery
  • Heat shock proteins research

Several recent papers highlight the focus on cellular communication and cardiac health:

  • Novel Protocols for Scalable Production of High Quality Purified Small Extracellular Vesicles from Bovine Milk, 2021, Nanotheranostics
  • Peptidic Connexin43 Therapeutics in Cardiac Reparative Medicine, 2021, Journal of Cardiovascular Development and Disease
  • Cx43 and the Actin Cytoskeleton: Novel Roles and Implications for Cell-Cell Junction-Based Barrier Function Regulation, 2020, Biomolecules
  • Connexin 43 confers chemoresistance through activating PI3K, 2022, Oncogenesis
  • The connexin 43 carboxyl terminal mimetic peptide αCT1 prompts differentiation of a collagen scar matrix in humans resembling unwounded skin, 2021, The FASEB Journal

They have published frequently in venues such as Circulation Research with 11 publications, bioRxiv (Cold Spring Harbor Laboratory) with 9 publications, Circulation with 6, Journal of Cardiovascular Development and Disease with 2, and Biomolecules with 2.

Frequent collaborators include Steven Poelzing, Xiaobo Wu, Gregory S. Hoeker, Jane Jourdan, and Samy Lamouille, with collaboration counts ranging from 9 to 14 publications.

Best Publications

  • Pericardial Mesoderm Generates a Population of Coronary Smooth Muscle Cells Migrating into the Heart along with Ingrowth of the Epicardial Organ

    Takashi Mikawa;Robert G. Gourdie

  • Epicardium-Derived Cells Contribute a Novel Population to the Myocardial Wall and the Atrioventricular Cushions

    A. C. Gittenberger-De Groot;M.-P. F. M. Vrancken Peeters;M. M. T. Mentink;R. G. Gourdie

  • Guidelines for experimental models of myocardial ischemia and infarction.

    Merry L. Lindsey;Merry L. Lindsey;Roberto Bolli;John M. Canty;Xiao Jun Du

  • Zonula occludens-1 alters connexin43 gap junction size and organization by influencing channel accretion.

    Andrew W. Hunter;Ralph J. Barker;Ching Zhu;Robert G. Gourdie

  • The spatial distribution and relative abundance of gap-junctional connexin40 and connexin43 correlate to functional properties of components of the cardiac atrioventricular conduction system.

    Robert G. Gourdie;Nicholas J. Severs;Colin R. Green;Stephen Rothery

  • Novel therapeutic strategies targeting fibroblasts and fibrosis in heart disease.

    Robert G. Gourdie;Stefanie Dimmeler;Peter Kohl

  • Connexin 43 connexon to gap junction transition is regulated by zonula occludens-1

    J. Matthew Rhett;L. Jane Jourdan;Robert G. Gourdie

  • Novel therapies for scar reduction and regenerative healing of skin wounds

    J. Matthew Rhett;Gautam S. Ghatnekar;Joseph A. Palatinus;Michael O’Quinn

  • Dissociated Spatial Patterning of Gap Junctions and Cell Adhesion Junctions During Postnatal Differentiation of Ventricular Myocardium

    Brigitt D. Angst;Laeeq U.R. Khan;Nicholas J. Severs;Kate Whitely

  • Nkx2-5 mutation causes anatomic hypoplasia of the cardiac conduction system

    Patrick Y. Jay;Brett S. Harris;Colin T. Maguire;Antje Buerger

  • Heart and neural tube defects in transgenic mice overexpressing the Cx43 gap junction gene

    J. L. Ewart;M. F. Cohen;R. A. Meyer;G. Y. Huang

  • Altered patterns of cardiac intercellular junction distribution in hypertrophic cardiomyopathy.

    R. Sepp;N. J. Severs;R. G. Gourdie

  • Functional and morphological evidence for a ventricular conduction system in zebrafish and Xenopus hearts

    David Sedmera;Maria Reckova;Maria Reckova;Maria Reckova;Angela deAlmeida;Angela deAlmeida;Angela deAlmeida;Martina Sedmerova

  • Terminal diversification of the myocyte lineage generates Purkinje fibers of the cardiac conduction system.

    R.G. Gourdie;T. Mima;R.P. Thompson;T. Mikawa

  • Endothelin-induced conversion of embryonic heart muscle cells into impulse-conducting Purkinje fibers

    Robert G. Gourdie;Yan Wei;Darlene Kim;Sandra C. Klatt

  • Immunolabelling patterns of gap junction connexins in the developing and mature rat heart.

    Robert G. Gourdie;Colin R. Green;Nicholas J. Severs;Robert P. Thompson

  • Increased association of ZO-1 with connexin43 during remodeling of cardiac gap junctions.

    Ralph J. Barker;Robert L. Price;Robert G. Gourdie

  • Connexin45 (alpha 6) expression delineates an extended conduction system in the embryonic and mature rodent heart.

    Steven R. Coppen;Nicholas J. Severs;Robert G. Gourdie

  • Hemodynamics Is a Key Epigenetic Factor in Development of the Cardiac Conduction System

    Maria Reckova;Carlin Rosengarten;Angela deAlmeida;Chiffvon P. Stanley

  • Fibroblast–myocyte electrotonic coupling: Does it occur in native cardiac tissue?

    Peter Kohl;Robert G. Gourdie

Frequent Co-Authors

Takashi Mikawa
Takashi Mikawa University of California, San Francisco
Lori L. Isom
Lori L. Isom University of Michigan–Ann Arbor
Seigo Izumo
Seigo Izumo Beth Israel Deaconess Medical Center
James P. Keener
James P. Keener University of Utah
Kevin L. Schey
Kevin L. Schey Vanderbilt University
Justin D. Lathia
Justin D. Lathia Cleveland Clinic Lerner College of Medicine
Francis G. Spinale
Francis G. Spinale University of South Carolina
Kenneth R. Chien
Kenneth R. Chien Karolinska Institute
Margaret L. Kirby
Margaret L. Kirby Duke University

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