World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
102
Citations
34534
World Ranking
7724
National Ranking
4018

Francis G. Spinale publication distribution in Medicine in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Medicine in 2026. The highlighted bar marks where Francis G. Spinale sits on this spectrum.

101–120 publications: 5 scientists 121–140 publications: 26 scientists 141–160 publications: 73 scientists 161–180 publications: 155 scientists 181–200 publications: 230 scientists 201–220 publications: 363 scientists 221–240 publications: 487 scientists 241–260 publications: 545 scientists 261–280 publications: 722 scientists 281–300 publications: 768 scientists 301–320 publications: 834 scientists 321–340 publications: 895 scientists 341–360 publications: 922 scientists 361–380 publications: 838 scientists 381–400 publications: 861 scientists 401–420 publications: 918 scientists 421–440 publications: 806 scientists 441–460 publications: 771 scientists 461–480 publications: 751 scientists 481–500 publications: 713 scientists 501–520 publications: 617 scientists 521–540 publications: 611 scientists 541–560 publications: 537 scientists 561–580 publications: 504 scientists 581–600 publications: 509 scientists 601–620 publications: 396 scientists 621–640 publications: 386 scientists 641–660 publications: 371 scientists 661–680 publications: 340 scientists 681–700 publications: 336 scientists 701–720 publications: 307 scientists 721–740 publications: 259 scientists 741–760 publications: 230 scientists 761–780 publications: 228 scientists 781–800 publications: 217 scientists 801–820 publications: 204 scientists 821–840 publications: 186 scientists 841–860 publications: 177 scientists 861–880 publications: 155 scientists 881–900 publications: 139 scientists 901–920 publications: 145 scientists 921–940 publications: 116 scientists 941–960 publications: 133 scientists 961–980 publications: 91 scientists 981–1,000 publications: 96 scientists 1,001–1,020 publications: 77 scientists 1,021–1,040 publications: 70 scientists 1,041–1,060 publications: 63 scientists 1,061–1,080 publications: 77 scientists 1,081–1,100 publications: 49 scientists 1,101–1,120 publications: 54 scientists 1,121–1,140 publications: 49 scientists 1,141–1,160 publications: 51 scientists 1,161–1,180 publications: 35 scientists 1,181–1,200 publications: 39 scientists 1,201–1,220 publications: 26 scientists 1,221–1,240 publications: 37 scientists 1,241–1,260 publications: 36 scientists 1,261–1,280 publications: 27 scientists 1,281–1,300 publications: 32 scientists 1,301–1,320 publications: 28 scientists 1,321–1,340 publications: 17 scientists 1,341–1,360 publications: 30 scientists 1,361–1,380 publications: 28 scientists 1,381–1,400 publications: 17 scientists 1,401–1,420 publications: 21 scientists 1,421–1,440 publications: 15 scientists 1,441–1,460 publications: 12 scientists 1,461–1,480 publications: 12 scientists 1,481–1,500 publications: 18 scientists 1,501–1,520 publications: 14 scientists 1,521–1,540 publications: 17 scientists 1,541–1,560 publications: 15 scientists 1,561–1,580 publications: 6 scientists 1,581–1,600 publications: 2 scientists 1,601–1,620 publications: 12 scientists 1,621–1,640 publications: 11 scientists 1,641–1,660 publications: 8 scientists 1,661–1,680 publications: 5 scientists 1,681–1,700 publications: 5 scientists 1,701–1,720 publications: 10 scientists 1,721–1,740 publications: 12 scientists 1,741–1,760 publications: 14 scientists 1,761–1,780 publications: 6 scientists 1,781–1,795 publications: 5 scientists 1,796+ publications: 100 scientists
101 publications 1,796+

This scientist: 603 publications — 72nd percentile

72% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,796 publications or more.

Francis G. Spinale D-index placement in Medicine in 2026

The chart shows the D-index (discipline H-index) distribution of Medicine scientists ranked by Research.com in 2026. The highlighted bar marks where Francis G. Spinale sits on this spectrum.

70–71 D-Index: 226 scientists 72–73 D-Index: 391 scientists 74–75 D-Index: 574 scientists 76–77 D-Index: 730 scientists 78–79 D-Index: 891 scientists 80–81 D-Index: 972 scientists 82–83 D-Index: 1,027 scientists 84–85 D-Index: 1,003 scientists 86–87 D-Index: 960 scientists 88–89 D-Index: 970 scientists 90–91 D-Index: 922 scientists 92–93 D-Index: 839 scientists 94–95 D-Index: 808 scientists 96–97 D-Index: 779 scientists 98–99 D-Index: 668 scientists 100–101 D-Index: 611 scientists 102–103 D-Index: 630 scientists 104–105 D-Index: 513 scientists 106–107 D-Index: 541 scientists 108–109 D-Index: 445 scientists 110–111 D-Index: 429 scientists 112–113 D-Index: 400 scientists 114–115 D-Index: 393 scientists 116–117 D-Index: 318 scientists 118–119 D-Index: 302 scientists 120–121 D-Index: 287 scientists 122–123 D-Index: 255 scientists 124–125 D-Index: 256 scientists 126–127 D-Index: 252 scientists 128–129 D-Index: 230 scientists 130–131 D-Index: 179 scientists 132–133 D-Index: 168 scientists 134–135 D-Index: 163 scientists 136–137 D-Index: 159 scientists 138–139 D-Index: 134 scientists 140–141 D-Index: 134 scientists 142–143 D-Index: 118 scientists 144–145 D-Index: 109 scientists 146–147 D-Index: 106 scientists 148–149 D-Index: 74 scientists 150–151 D-Index: 79 scientists 152–153 D-Index: 80 scientists 154–155 D-Index: 87 scientists 156–157 D-Index: 57 scientists 158–159 D-Index: 74 scientists 160–161 D-Index: 69 scientists 162–163 D-Index: 60 scientists 164–165 D-Index: 53 scientists 166–167 D-Index: 39 scientists 168–169 D-Index: 42 scientists 170–171 D-Index: 32 scientists 172–173 D-Index: 39 scientists 174–175 D-Index: 40 scientists 176–177 D-Index: 28 scientists 178–179 D-Index: 19 scientists 180–181 D-Index: 23 scientists 182–183 D-Index: 31 scientists 184–185 D-Index: 18 scientists 186–187 D-Index: 20 scientists 188–189 D-Index: 22 scientists 190–191 D-Index: 13 scientists 192–193 D-Index: 21 scientists 194–195 D-Index: 12 scientists 196–197 D-Index: 12 scientists 198–199 D-Index: 14 scientists 200–201 D-Index: 15 scientists 202–203 D-Index: 13 scientists 204–205 D-Index: 10 scientists 206–207 D-Index: 8 scientists 208–209 D-Index: 4 scientists 210–211 D-Index: 12 scientists 212–213 D-Index: 11 scientists 214–215 D-Index: 10 scientists 216 D-Index: 4 scientists 217+ D-Index: 98 scientists
70 D-Index 217+

This scientist: 102 D-Index — 63rd percentile

63% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 217 D-Index or more.

Overview

Francis G. Spinale is affiliated with the University of South Carolina in the United States. Their research work is concentrated primarily in the field of Medicine, with a significant focus on Cardiology and Cardiovascular Medicine, Surgery, Oncology, Molecular Biology, and Pulmonary and Respiratory Medicine.

The scientist's scholarly output includes a substantial number of publications addressing cardiovascular and related biomedical topics. Their work covers a variety of specialized topics such as:

  • Cardiovascular Function and Risk Factors
  • Cardiac Fibrosis and Remodeling
  • Peptidase Inhibition and Analysis
  • Cardiac Structural Anomalies and Repair
  • Cardiovascular Disease and Adiposity
  • Tissue Engineering and Regenerative Medicine
  • Stress Responses and Cortisol

Among the notable recent papers co-authored by Spinale are:

  • Guidelines for in vivo mouse models of myocardial infarction, 2021, American Journal of Physiology-Heart and Circulatory Physiology
  • Dual Angiotensin Receptor-Neprilysin Inhibition With Sacubitril/Valsartan Attenuates Systolic Dysfunction in Experimental Doxorubicin-Induced Cardiotoxicity, 2020, JACC CardioOncology
  • Reperfused vs. nonreperfused myocardial infarction: when to use which model, 2021, American Journal of Physiology-Heart and Circulatory Physiology
  • Changes in Myocardial Microstructure and Mechanics With Progressive Left Ventricular Pressure Overload, 2020, JACC Basic to Translational Science
  • Ensemble machine learning model identifies patients with HFpEF from matrix-related plasma biomarkers, 2022, American Journal of Physiology-Heart and Circulatory Physiology

Frequent venues where Spinale has published include:

  • Circulation
  • Physiology
  • American Journal of Physiology-Heart and Circulatory Physiology
  • JACC Basic to Translational Science
  • Zenodo (CERN European Organization for Nuclear Research)

Collaboration is a significant aspect of Spinale's scientific activity. Some of their frequent co-authors include Lisa Freeburg, Tarek Shazly, Albert J. Sinusas, Amelia Churillo, and Shayne C. Barlow.

Best Publications

  • Myocardial Matrix Remodeling and the Matrix Metalloproteinases: Influence on Cardiac Form and Function

    Francis G. Spinale

  • Pathophysiologically relevant concentrations of tumor necrosis factor- α promote progressive left ventricular dysfunction and remodeling in rats

    Biykem Bozkurt;Scott B. Kribbs;Fred J. Clubb;Lloyd H. Michael

  • Matrix Metalloproteinases: Regulation and Dysregulation in the Failing Heart

    Francis G. Spinale

  • A Matrix Metalloproteinase Induction/Activation System Exists in the Human Left Ventricular Myocardium and Is Upregulated in Heart Failure

    Francis G. Spinale;Mytsi L. Coker;Lena J. Heung;Brian R. Bond

  • Increased matrix metalloproteinase activity and selective upregulation in LV myocardium from patients with end-stage dilated cardiomyopathy.

    Chadwick V. Thomas;Mytsi L. Coker;James L. Zellner;John R. Handy

  • Time-Dependent Changes in Matrix Metalloproteinase Activity and Expression During the Progression of Congestive Heart Failure: Relation to Ventricular and Myocyte Function

    Francis G. Spinale;Mytsi L. Coker;Chadwick V. Thomas;Jennifer D. Walker

  • Matrix Metalloproteinases/Tissue Inhibitors of Metalloproteinases: Relationship Between Changes in Proteolytic Determinants of Matrix Composition and Structural, Functional, and Clinical Manifestations of Hypertensive Heart Disease

    S. Hinan Ahmed;Leslie L. Clark;Weems R. Pennington;Carson S. Webb

  • Primary Results From the SmartDelay Determined AV Optimization: A Comparison to Other AV Delay Methods Used in Cardiac Resynchronization Therapy (SMART-AV) Trial A Randomized Trial Comparing Empirical, Echocardiography-Guided, and Algorithmic Atrioventricular Delay Programming in Cardiac Resynchronization Therapy

    Kenneth A. Ellenbogen;Michael R. Gold;Timothy E. Meyer;Ignacio Fernández Lozano

  • Left Ventricular Remodeling in Transgenic Mice With Cardiac Restricted Overexpression of Tumor Necrosis Factor

    Natarajan Sivasubramanian;Mytsi L. Coker;Karla M. Kurrelmeyer;William R. MacLellan

  • Matrix Metalloproteinase Inhibition During the Development of Congestive Heart Failure Effects on Left Ventricular Dimensions and Function

    Francis G. Spinale;Mytsi L. Coker;Stephen R. Krombach;Rupak Mukherjee

  • Injectable and bioresponsive hydrogels for on-demand matrix metalloproteinase inhibition

    Brendan P. Purcell;David Lobb;Manoj B. Charati;Shauna M. Dorsey

  • Animal Models of Heart Failure A Scientific Statement From the American Heart Association

    Steven R. Houser;Kenneth B. Margulies;Anne M. Murphy;Francis G. Spinale

  • Matrix Metalloproteinase Inhibition Attenuates Left Ventricular Remodeling and Dysfunction in a Rat Model of Progressive Heart Failure

    J. Thomas Peterson;Hussein Hallak;Linda Johnson;Hua Li

  • Large Animal Models of Heart Failure A Critical Link in the Translation of Basic Science to Clinical Practice

    Jennifer A. Dixon;Francis G. Spinale

  • Arrhythmia-Induced Cardiomyopathies: Mechanisms, Recognition, and Management

    Rakesh Gopinathannair;Susan P. Etheridge;Francis E. Marchlinski;Francis G. Spinale

  • Myocardial Infarct Expansion and Matrix Metalloproteinase Inhibition

    Rupak Mukherjee;Theresa A. Brinsa;Kathryn B. Dowdy;Amelia A. Scott

  • Myocardial matrix degradation and metalloproteinase activation in the failing heart: a potential therapeutic target

    Francis G Spinale;Mytsi L Coker;Brian R Bond;James L Zellner

  • Specific Temporal Profile of Matrix Metalloproteinase Release Occurs in Patients After Myocardial Infarction Relation to Left Ventricular Remodeling

    Carson S. Webb;David D. Bonnema;S. Hinan Ahmed;Amy H. Leonardi

  • Cardioprotective and Antiapoptotic Effects of Heme Oxygenase-1 in the Failing Heart

    Guangwu Wang;Tariq Hamid;Rachel J. Keith;Guihua Zhou

  • Region- and Type-Specific Induction of Matrix Metalloproteinases in Post–Myocardial Infarction Remodeling

    Eric M. Wilson;Sina L. Moainie;Julia M. Baskin;Abigail S. Lowry

Frequent Co-Authors

Michael R. Zile
Michael R. Zile Medical University of South Carolina
Scott Reeves
Scott Reeves St George's, University of London
Joseph H. Gorman
Joseph H. Gorman University of Pennsylvania
Robert C. Gorman
Robert C. Gorman University of Pennsylvania
Merry L. Lindsey
Merry L. Lindsey University of Nebraska Medical Center
Blase A. Carabello
Blase A. Carabello Baylor College of Medicine
Jason A. Burdick
Jason A. Burdick University of Colorado Boulder
Douglas L. Mann
Douglas L. Mann Washington University in St. Louis
Michael R. Gold
Michael R. Gold Medical University of South Carolina
Joseph E. Bavaria
Joseph E. Bavaria University of Pennsylvania

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