World's Best Scientists 2026 revealed!

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Immunology

D-Index
86
Citations
26072
World Ranking
1269
National Ranking
48

Medicine

D-Index
86
Citations
26162
World Ranking
14169
National Ranking
541

Overview

Filippo Belardelli is affiliated with the National Research Council (CNR) in Italy. Their research spans multiple fields including medicine and immunology and microbiology, with a focus on several subfields such as immunology, oncology, infectious diseases, molecular biology, and epidemiology. Their work covers a variety of key topics related to COVID-19 clinical research studies, T-cell and B-cell immunology, SARS-CoV-2 and COVID-19 research, interferon and immune responses, cytokine signaling pathways and interactions, immune cell function and interaction, and single-cell and spatial transcriptomics.

The scientist has published papers in several frequent venues, including:

  • Cytokine & Growth Factor Reviews
  • Journal of Immunology Research
  • Frontiers in Oncology
  • Cancers
  • International Immunology

Recent significant papers authored by Filippo Belardelli include:

  • Are we fully exploiting type I Interferons in today's fight against COVID-19 pandemic?, 2020, Cytokine & Growth Factor Reviews
  • Type I Interferons as Joint Regulators of Tumor Growth and Obesity, 2021, Cancers
  • Multicentre Harmonisation of a Six-Colour Flow Cytometry Panel for Naïve/Memory T Cell Immunomonitoring, 2020, Journal of Immunology Research
  • Type I interferons induce peripheral T regulatory cell differentiation under tolerogenic conditions, 2020, International Immunology
  • Exploiting natural antiviral immunity for the control of pandemics: Lessons from Covid-19, 2021, Cytokine & Growth Factor Reviews

Among frequent collaborators, Filippo Belardelli works with:

  • Francesca Urbani
  • Luciano Castiello
  • Eleonora Aricò
  • Laura Bracci
  • Iole Macchia

The scientist's main fields of study emphasize a strong focus on medicine and immunology and microbiology, where their contributions are evident across thirteen and ten publications respectively.

Subfield specialization includes immunology with ten publications, oncology with six, infectious diseases with five, followed by molecular biology and epidemiology.

Themes central to their research revolve around complex immune system mechanisms and viral pathogenesis, particularly in the context of COVID-19 and immune modulation by interferons.

Best Publications

  • Type i interferons potently enhance humoral immunity and can promote isotype switching by stimulating dendritic cells in vivo.

    Agnes Le Bon;Giovanna Schiavoni;Giuseppina D'Agostino;Ion Gresser

  • Immune-based mechanisms of cytotoxic chemotherapy: implications for the design of novel and rationale-based combined treatments against cancer

    L Bracci;G Schiavoni;A Sistigu;F Belardelli

  • Cancer cell–autonomous contribution of type I interferon signaling to the efficacy of chemotherapy

    Antonella Sistigu;Takahiro Yamazaki;Erika Vacchelli;Kariman Chaba

  • Type I Interferon as a Powerful Adjuvant for Monocyte-Derived Dendritic Cell Development and Activity in Vitro and in Hu-Pbl-Scid Mice

    Stefano M. Santini;Caterina Lapenta;Mariantonia Logozzi;Stefania Parlato

  • Type I interferons produced by dendritic cells promote their phenotypic and functional activation.

    Maria Montoya;Giovanna Schiavoni;Fabrizio Mattei;Ion Gresser

  • Role of interferons and other cytokines in the regulation of the immune response.

    Filippo Belardelli

  • IL-15 is expressed by dendritic cells in response to type I IFN, double-stranded RNA, or lipopolysaccharide and promotes dendritic cell activation.

    Fabrizio Mattei;Giovanna Schiavoni;Filippo Belardelli;David F. Tough

  • Effect of Proton Pump Inhibitor Pretreatment on Resistance of Solid Tumors to Cytotoxic Drugs

    Francesca Luciani;Massimo Spada;Angelo De Milito;Agnese Molinari

  • The neglected role of type I interferon in the T-cell response: implications for its clinical use

    Filippo Belardelli;Ion Gresser

  • ICSBP Is Essential for the Development of Mouse Type I Interferon-producing Cells and for the Generation and Activation of CD8α+ Dendritic Cells

    Giovanna Schiavoni;Fabrizio Mattei;Paola Sestili;Paola Borghi

  • Cytokines as a link between innate and adaptive antitumor immunity.

    Filippo Belardelli;Maria Ferrantini

  • Interferon-alpha in tumor immunity and immunotherapy.

    Filippo Belardelli;Maria Ferrantini;Enrico Proietti;John M Kirkwood

  • Interferon-α and cancer : Mechanisms of action and new perspectives of clinical use

    Maria Ferrantini;Imerio Capone;Filippo Belardelli

  • Cyclophosphamide Synergizes with Type I Interferons through Systemic Dendritic Cell Reactivation and Induction of Immunogenic Tumor Apoptosis

    Giovanna Schiavoni;Antonella Sistigu;Mara Valentini;Fabrizio Mattei

  • Expression of CCR-7, MIP-3β, and Th-1 chemokines in type I IFN-induced monocyte-derived dendritic cells: importance for the rapid acquisition of potent migratory and functional activities

    Stefania Parlato;Stefano M. Santini;Caterina Lapenta;Tiziana Di Pucchio

  • Cyclophosphamide enhances the antitumor efficacy of adoptively transferred immune cells through the induction of cytokine expression, B-cell and T-cell homeostatic proliferation, and specific tumor infiltration.

    Laura Bracci;Federica Moschella;Paola Sestili;Valentina La Sorsa

  • European Code against Cancer 4th edition: 12 ways to reduce your cancer risk §

    Joachim Schüz;Carolina Espina;Patricia Villain;Rolando Herrero

  • Type I IFN as a Natural Adjuvant for a Protective Immune Response: Lessons from the Influenza Vaccine Model

    Enrico Proietti;Laura Bracci;Simona Puzelli;Tiziana Di Pucchio

  • Cyclophosphamide induces type I interferon and augments the number of CD44hi T lymphocytes in mice: implications for strategies of chemoimmunotherapy of cancer

    Giovanna Schiavoni;Fabrizio Mattei;Tiziana Di Pucchio;Stefano M. Santini

  • A Contribution of Mouse Dendritic Cell–Derived IL-2 for NK Cell Activation

    Francesca Granucci;Ivan Zanoni;Norman Pavelka;Serani L.H. van Dommelen

  • IL-12 induces IFN-gamma expression and secretion in mouse peritoneal macrophages.

    P Puddu;L Fantuzzi;P Borghi;B Varano

Frequent Co-Authors

Sandra Gessani
Sandra Gessani Istituto Superiore di Sanità
Stefano Fais
Stefano Fais Istituto Superiore di Sanità
Giorgio Parmiani
Giorgio Parmiani University of Siena
Ion Gresser
Ion Gresser Grenoble Alpes University
Walter Malorni
Walter Malorni University of Rome Tor Vergata
Ugo Testa
Ugo Testa Istituto Superiore di Sanità
Licia Rivoltini
Licia Rivoltini Fondazione IRCCS Istituto Nazionale dei Tumori
Mario P. Colombo
Mario P. Colombo Fondazione IRCCS Istituto Nazionale dei Tumori
David F. Tough
David F. Tough GlaxoSmithKline (United Kingdom)
Piero Musiani
Piero Musiani University of Chieti-Pescara

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