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David F. Tough

D-Index & Metrics

Discipline name D-Index World Ranking Current World Ranking National Ranking Current National Ranking Publications Citations
Immunology 68 2552 2346 222 215 137 23199

David F. Tough publications per year

The chart shows the history of publications by David F. Tough between 1986 and 2025, highlighting the no. of papers published in each year and offering an overview of the publication velocity of this scholar. David F. Tough published across 40 years, from 1986 to 2025, averaging 4.1 papers a year. Output peaked at 15 publications in 2006. 5 of the 162 publications appeared in the last two years.

No. of publications
5 10 15
Bar chart. Horizontal axis: year, 1986 to 2025. Vertical axis: number of publications, 0 to 15. Peak 15 publications in 2006. 1986: 1 publication 1987: 0 publications 1988: 0 publications 1989: 0 publications 1990: 0 publications 1991: 0 publications 1992: 1 publication 1993: 0 publications 1994: 3 publications 1995: 5 publications 1996: 4 publications 1997: 2 publications 1998: 7 publications 1999: 1 publication 2000: 4 publications 2001: 6 publications 2002: 8 publications 2003: 7 publications 2004: 6 publications 2005: 7 publications 2006: 15 publications 2007: 6 publications 2008: 5 publications 2009: 5 publications 2010: 2 publications 2011: 4 publications 2012: 3 publications 2013: 3 publications 2014: 4 publications 2015: 3 publications 2016: 3 publications 2017: 4 publications 2018: 4 publications 2019: 3 publications 2020: 11 publications 2021: 7 publications 2022: 11 publications 2023: 2 publications 2024: 1 publication 2025: 4 publications
1986 2025

162 publications in total across all disciplines

View publications per year as a table
David F. Tough: publications per year, 1986 to 2025
Year Publications
1986 1
1987 0
1988 0
1989 0
1990 0
1991 0
1992 1
1993 0
1994 3
1995 5
1996 4
1997 2
1998 7
1999 1
2000 4
2001 6
2002 8
2003 7
2004 6
2005 7
2006 15
2007 6
2008 5
2009 5
2010 2
2011 4
2012 3
2013 3
2014 4
2015 3
2016 3
2017 4
2018 4
2019 3
2020 11
2021 7
2022 11
2023 2
2024 1
2025 4
Total 162
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David F. Tough publication distribution in Immunology in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Immunology in 2026. The highlighted bar marks where David F. Tough sits on this spectrum.

No. of scientists
50 100 150
Bar chart with 76 bars. Horizontal axis: publications, 62–71 to 807+. Vertical axis: number of scientists, 0 to 189. Most scientists, 189, have 152–161 publications. The last bar groups every scientist with 807 publications or more. The highlighted bar, 132–141 publications, is where this scientist sits. 62–71 publications: 9 scientists 72–81 publications: 23 scientists 82–91 publications: 40 scientists 92–101 publications: 72 scientists 102–111 publications: 86 scientists 112–121 publications: 108 scientists 122–131 publications: 150 scientists 132–141 publications: 160 scientists 142–151 publications: 159 scientists 152–161 publications: 189 scientists 162–171 publications: 166 scientists 172–181 publications: 181 scientists 182–191 publications: 188 scientists 192–201 publications: 187 scientists 202–211 publications: 178 scientists 212–221 publications: 158 scientists 222–231 publications: 168 scientists 232–241 publications: 159 scientists 242–251 publications: 160 scientists 252–261 publications: 148 scientists 262–271 publications: 116 scientists 272–281 publications: 125 scientists 282–291 publications: 115 scientists 292–301 publications: 111 scientists 302–311 publications: 95 scientists 312–321 publications: 97 scientists 322–331 publications: 97 scientists 332–341 publications: 99 scientists 342–351 publications: 96 scientists 352–361 publications: 69 scientists 362–371 publications: 76 scientists 372–381 publications: 71 scientists 382–391 publications: 71 scientists 392–401 publications: 62 scientists 402–411 publications: 54 scientists 412–421 publications: 41 scientists 422–431 publications: 63 scientists 432–441 publications: 53 scientists 442–451 publications: 31 scientists 452–461 publications: 42 scientists 462–471 publications: 40 scientists 472–481 publications: 29 scientists 482–491 publications: 34 scientists 492–501 publications: 30 scientists 502–511 publications: 23 scientists 512–521 publications: 41 scientists 522–531 publications: 29 scientists 532–541 publications: 28 scientists 542–551 publications: 16 scientists 552–561 publications: 18 scientists 562–571 publications: 18 scientists 572–581 publications: 17 scientists 582–591 publications: 17 scientists 592–601 publications: 17 scientists 602–611 publications: 19 scientists 612–621 publications: 13 scientists 622–631 publications: 12 scientists 632–641 publications: 11 scientists 642–651 publications: 16 scientists 652–661 publications: 9 scientists 662–671 publications: 5 scientists 672–681 publications: 13 scientists 682–691 publications: 12 scientists 692–701 publications: 6 scientists 702–711 publications: 6 scientists 712–721 publications: 9 scientists 722–731 publications: 9 scientists 732–741 publications: 6 scientists 742–751 publications: 11 scientists 752–761 publications: 10 scientists 762–771 publications: 7 scientists 772–781 publications: 12 scientists 782–791 publications: 7 scientists 792–801 publications: 5 scientists 802–806 publications: 1 scientist 807+ publications: 100 scientists
62–71 publications 807+

This scientist: 137 publications — 12th percentile

12% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 807 publications or more.

View publications distribution as a table
Number of Immunology scientists by publication count, Research.com 2026 ranking edition. Based on 4,929 ranked scientists.
Publications Scientists This scientist
62–71 9
72–81 23
82–91 40
92–101 72
102–111 86
112–121 108
122–131 150
132–141 160 137
142–151 159
152–161 189
162–171 166
172–181 181
182–191 188
192–201 187
202–211 178
212–221 158
222–231 168
232–241 159
242–251 160
252–261 148
262–271 116
272–281 125
282–291 115
292–301 111
302–311 95
312–321 97
322–331 97
332–341 99
342–351 96
352–361 69
362–371 76
372–381 71
382–391 71
392–401 62
402–411 54
412–421 41
422–431 63
432–441 53
442–451 31
452–461 42
462–471 40
472–481 29
482–491 34
492–501 30
502–511 23
512–521 41
522–531 29
532–541 28
542–551 16
552–561 18
562–571 18
572–581 17
582–591 17
592–601 17
602–611 19
612–621 13
622–631 12
632–641 11
642–651 16
652–661 9
662–671 5
672–681 13
682–691 12
692–701 6
702–711 6
712–721 9
722–731 9
732–741 6
742–751 11
752–761 10
762–771 7
772–781 12
782–791 7
792–801 5
802–806 1
807+ 100
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David F. Tough D-index placement in Immunology in 2026

The chart shows the D-index (discipline H-index) distribution of Immunology scientists ranked by Research.com in 2026. The highlighted bar marks where David F. Tough sits on this spectrum.

No. of scientists
50 100 150 200
Bar chart with 60 bars. Horizontal axis: D-Index, 40–41 to 157+. Vertical axis: number of scientists, 0 to 201. Most scientists, 201, have 58–59 D-Index. The last bar groups every scientist with 157 D-Index or more. The highlighted bar, 68–69 D-Index, is where this scientist sits. 40–41 D-Index: 28 scientists 42–43 D-Index: 91 scientists 44–45 D-Index: 157 scientists 46–47 D-Index: 192 scientists 48–49 D-Index: 175 scientists 50–51 D-Index: 188 scientists 52–53 D-Index: 177 scientists 54–55 D-Index: 155 scientists 56–57 D-Index: 194 scientists 58–59 D-Index: 201 scientists 60–61 D-Index: 197 scientists 62–63 D-Index: 201 scientists 64–65 D-Index: 173 scientists 66–67 D-Index: 167 scientists 68–69 D-Index: 172 scientists 70–71 D-Index: 199 scientists 72–73 D-Index: 184 scientists 74–75 D-Index: 133 scientists 76–77 D-Index: 163 scientists 78–79 D-Index: 127 scientists 80–81 D-Index: 121 scientists 82–83 D-Index: 125 scientists 84–85 D-Index: 121 scientists 86–87 D-Index: 102 scientists 88–89 D-Index: 96 scientists 90–91 D-Index: 75 scientists 92–93 D-Index: 72 scientists 94–95 D-Index: 74 scientists 96–97 D-Index: 66 scientists 98–99 D-Index: 68 scientists 100–101 D-Index: 49 scientists 102–103 D-Index: 60 scientists 104–105 D-Index: 54 scientists 106–107 D-Index: 36 scientists 108–109 D-Index: 23 scientists 110–111 D-Index: 52 scientists 112–113 D-Index: 41 scientists 114–115 D-Index: 34 scientists 116–117 D-Index: 25 scientists 118–119 D-Index: 28 scientists 120–121 D-Index: 11 scientists 122–123 D-Index: 20 scientists 124–125 D-Index: 27 scientists 126–127 D-Index: 19 scientists 128–129 D-Index: 20 scientists 130–131 D-Index: 16 scientists 132–133 D-Index: 17 scientists 134–135 D-Index: 14 scientists 136–137 D-Index: 15 scientists 138–139 D-Index: 9 scientists 140–141 D-Index: 11 scientists 142–143 D-Index: 9 scientists 144–145 D-Index: 9 scientists 146–147 D-Index: 7 scientists 148–149 D-Index: 7 scientists 150–151 D-Index: 7 scientists 152–153 D-Index: 5 scientists 154–155 D-Index: 8 scientists 156 D-Index: 6 scientists 157+ D-Index: 96 scientists
40–41 D-Index 157+

This scientist: 68 D-Index — 49th percentile

49% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 157 D-Index or more.

View D-Index distribution as a table
Number of Immunology scientists by D-index, Research.com 2026 ranking edition. Based on 4,929 ranked scientists.
D-Index Scientists This scientist
40–41 28
42–43 91
44–45 157
46–47 192
48–49 175
50–51 188
52–53 177
54–55 155
56–57 194
58–59 201
60–61 197
62–63 201
64–65 173
66–67 167
68–69 172 68
70–71 199
72–73 184
74–75 133
76–77 163
78–79 127
80–81 121
82–83 125
84–85 121
86–87 102
88–89 96
90–91 75
92–93 72
94–95 74
96–97 66
98–99 68
100–101 49
102–103 60
104–105 54
106–107 36
108–109 23
110–111 52
112–113 41
114–115 34
116–117 25
118–119 28
120–121 11
122–123 20
124–125 27
126–127 19
128–129 20
130–131 16
132–133 17
134–135 14
136–137 15
138–139 9
140–141 11
142–143 9
144–145 9
146–147 7
148–149 7
150–151 7
152–153 5
154–155 8
156 6
157+ 96
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Overview

David F. Tough is affiliated with GlaxoSmithKline in the United Kingdom. Their research primarily spans the fields of Immunology and Microbiology, Biochemistry, Genetics and Molecular Biology, and Medicine.

The scientist's work is concentrated in several subfields, including Immunology, Molecular Biology, Rheumatology, Pathology and Forensic Medicine, and Virology. Their research topics cover:

  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • Protein Degradation and Inhibitors
  • Single-cell and spatial transcriptomics
  • Immune cells in cancer
  • Histone Deacetylase Inhibitors Research
  • Immunotherapy and Immune Responses

Recent notable publications authored or co-authored by David F. Tough include:

  • "Selective targeting of BD1 and BD2 of the BET proteins in cancer and immunoinflammation," 2020, Science
  • "Single-cell transcriptomics identifies an effectorness gradient shaping the response of CD4+ T cells to cytokines," 2020, Nature Communications
  • "Immune disease risk variants regulate gene expression dynamics during CD4+ T cell activation," 2022, Nature Genetics
  • "BACH2 drives quiescence and maintenance of resting Treg cells to promote homeostasis and cancer immunosuppression," 2020, The Journal of Experimental Medicine
  • "HDAC3 Mediates the Inflammatory Response and LPS Tolerance in Human Monocytes and Macrophages," 2020, Frontiers in Immunology

The scientist frequently publishes in several venues, including bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, Frontiers in Immunology, Annals of the Rheumatic Diseases, and Zenodo (CERN European Organization for Nuclear Research).

David F. Tough has collaborated frequently with several co-authors, notably:

  • Rab K. Prinjha
  • Nicola Harker
  • Wouter J. de Jonge
  • Gosia Trynka
  • Mohammed Ghiboub

Best Publications

  • Potent and Selective Stimulation of Memory-Phenotype CD8+ T Cells In Vivo by IL-15

    Xiaohong Zhang;Siquan Sun;Inkyu Hwang;David F Tough

  • Induction of Bystander T Cell Proliferation by Viruses and Type I Interferon in Vivo

    David F. Tough;Persephone Borrow;Jonathan Sprent

  • Type i interferons potently enhance humoral immunity and can promote isotype switching by stimulating dendritic cells in vivo.

    Agnes Le Bon;Giovanna Schiavoni;Giuseppina D'Agostino;Ion Gresser

  • Turnover of naive- and memory-phenotype T cells.

    David F. Tough;Jonathan Sprent

  • Cross-priming of CD8 + T cells stimulated by virus-induced type I interferon

    Agnes Le Bon;Nathalie Etchart;Nathalie Etchart;Cornelia Rossmann;Miranda Ashton

  • Links between innate and adaptive immunity via type I interferon

    Agnes Le Bon;David F Tough

  • Type I interferons produced by dendritic cells promote their phenotypic and functional activation.

    Maria Montoya;Giovanna Schiavoni;Fabrizio Mattei;Ion Gresser

  • Initial T cell frequency dictates memory CD8+ T cell lineage commitment.

    Amanda L Marzo;Kimberly D Klonowski;Agnes Le Bon;Persephone Borrow

  • IL-15 is expressed by dendritic cells in response to type I IFN, double-stranded RNA, or lipopolysaccharide and promotes dendritic cell activation.

    Fabrizio Mattei;Giovanna Schiavoni;Filippo Belardelli;David F. Tough

  • Developmental kinetics and lifespan of dendritic cells in mouse lymphoid organs.

    Arun T. Kamath;Sandrine Henri;Frank Battye;David F. Tough

  • Lymphocyte life-span and memory

    Jonathan Sprent;David F. Tough

  • The development, maturation, and turnover rate of mouse spleen dendritic cell populations

    Arun T. Kamath;Joanne Pooley;Meredith A. O’Keeffe;David Vremec

  • Type I Interferon-mediated Stimulation of T Cells by CpG DNA

    Siquan Sun;Xiaohong Zhang;David F. Tough;Jonathan Sprent

  • IL-15 Promotes the Survival of Naive and Memory Phenotype CD8+ T Cells

    Marion Berard;Katja Brandt;Silvia Bulfone-Paus;David F. Tough

  • Cutting edge: enhancement of antibody responses through direct stimulation of B and T cells by type I IFN.

    Agnes Le Bon;Clare Thompson;Elisabeth Kamphuis;Vanessa Durand

  • In vivo kinetics of human natural killer cells: the effects of ageing and acute and chronic viral infection

    Yan Zhang;Diana L. Wallace;Catherine M. De Lara;Hala Ghattas

  • T Cell Stimulation In Vivo by Lipopolysaccharide (LPS)

    David F. Tough;Siquan Sun;Jonathan Sprent

  • Selective targeting of BD1 and BD2 of the BET proteins in cancer and immunoinflammation

    Omer Gilan;Omer Gilan;Inmaculada Rioja;Kathy Knezevic;Matthew J. Bell

  • Direct stimulation of T cells by type I IFN enhances the CD8+ T cell response during cross-priming.

    Agnes Le Bon;Vanessa Durand;Elisabeth Kamphuis;Clare Thompson

  • Single-cell transcriptomics identifies an effectorness gradient shaping the response of CD4+ T cells to cytokines

    Eddie Cano-Gamez;Blagoje Soskic;Theodoros I. Roumeliotis;Ernest So

  • T cell death and memory.

    Jonathan Sprent;David F. Tough

Frequent Co-Authors

Jonathan Sprent
Jonathan Sprent Garvan Institute of Medical Research
Rab K. Prinjha
Rab K. Prinjha GlaxoSmithKline (United Kingdom)
Jagadeesh Bayry
Jagadeesh Bayry Indian Institute of Technology Palakkad
Filippo Belardelli
Filippo Belardelli National Research Council (CNR)
Persephone Borrow
Persephone Borrow University of Oxford
Peter C. L. Beverley
Peter C. L. Beverley Jenner Institute
Srini V. Kaveri
Srini V. Kaveri Centre national de la recherche scientifique, CNRS
Paul P. Tak
Paul P. Tak GlaxoSmithKline (United Kingdom)
Becca Asquith
Becca Asquith Imperial College London
George E. Griffin
George E. Griffin St George's, University of London

External Links

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Best Scientists Citing David F. Tough

Jonathan Sprent

Jonathan Sprent

Garvan Institute of Medical Research

Publications: 68

Filippo Belardelli

Filippo Belardelli

National Research Council (CNR)

Publications: 67

Rafi Ahmed

Rafi Ahmed

Emory University

Publications: 62

Ken Shortman

Ken Shortman

Walter and Eliza Hall Institute of Medical Research

Publications: 57

Jagadeesh Bayry

Jagadeesh Bayry

Indian Institute of Technology Palakkad

Publications: 56

Leo Lefrançois

Leo Lefrançois

University of Connecticut Health Center

Publications: 56

William R. Heath

William R. Heath

University of Melbourne

Publications: 52

Charles D. Surh

Charles D. Surh

Pohang University of Science and Technology

Publications: 50

Thomas A. Waldmann

Thomas A. Waldmann

National Institutes of Health

Publications: 50

Peter C. Doherty

Peter C. Doherty

University of Melbourne

Publications: 49

Arthur M. Krieg

Arthur M. Krieg

University of Massachusetts Chan Medical School

Publications: 49

Srini V. Kaveri

Srini V. Kaveri

Centre national de la recherche scientifique, CNRS

Publications: 49

Jacques Banchereau

Jacques Banchereau

Immunai

Publications: 38

Christopher K. Glass

Christopher K. Glass

University of California, San Diego

Publications: 37

Philippa Marrack

Philippa Marrack

National Jewish Health

Publications: 36

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Chien-Hsing Chang

Northwestern University

Publications: 35

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