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Neuroscience

D-Index
48
Citations
27555
World Ranking
6070
National Ranking
93

Overview

Isabel Varela-Nieto is affiliated with the Spanish National Research Council in Spain. Their research primarily addresses auditory systems and related molecular signaling pathways, with a focus on hearing loss and cochlear biology.

The scientist's main fields of study include Neuroscience, Medicine, and Biochemistry, Genetics and Molecular Biology. Their subfields of study highlight Sensory Systems, Molecular Biology, Neurology, Epidemiology, and Genetics. The core topics covered in their work are:

  • Hearing, Cochlea, Tinnitus, Genetics
  • Vestibular and auditory disorders
  • Meningioma and schwannoma management
  • Ear Surgery and Otitis Media
  • Neurofibromatosis and Schwannoma Cases
  • Connexins and lens biology
  • Neuroscience of respiration and sleep

Their publication record includes papers spanning from 2020 to 2023, with research appearing in venues such as Aging Cell, Expert Opinion on Drug Discovery, Genes, Antioxidants, and Cells. Recent notable papers include:

  • G6PD overexpression protects from oxidative stress and age-related hearing loss, 2020, Aging Cell
  • Drug development for noise-induced hearing loss, 2020, Expert Opinion on Drug Discovery
  • Insulin-like Growth Factor 1 Signaling in Mammalian Hearing, 2021, Genes
  • IGF-1 Controls Metabolic Homeostasis and Survival in HEI-OC1 Auditory Cells through AKT and mTOR Signaling, 2023, Antioxidants
  • IGF-1 Haploinsufficiency Causes Age-Related Chronic Cochlear Inflammation and Increases Noise-Induced Hearing Loss, 2021, Cells

The frequent publication venues for their work also include Frontiers in Cellular Neuroscience, Hearing Research, Frontiers in Cell and Developmental Biology, and DIGITAL.CSIC (Spanish National Research Council (CSIC)).

Collaborations are a significant aspect of their research, with frequent co-authors being Silvia Murillo-Cuesta, Lourdes Rodríguez-de la Rosa, Jose M. Bermúdez-Muñoz, Luis Lassaletta, and Julio Contreras.

In addition to articles, they have contributed to book publications, including participation in works published by Frontiers Media, notably the 2022 book Otologic Trauma, Pathology, and Therapy.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Development of auditory and vestibular systems

    Raymond Romand;Isabel Varela-Nieto

  • Delayed inner ear maturation and neuronal loss in postnatal Igf-1-deficient mice.

    Guadalupe Camarero;Carlos Avendaño;Carmen Fernández-Moreno;Angeles Villar

  • The role of glycosyl–phosphatidylinositol in signal transduction

    David R. Jones;Isabel Varela-Nieto

  • Sensorineural hearing loss in insulin-like growth factor I-null mice: a new model of human deafness.

    R Cediel;R Riquelme;J Contreras;J Contreras;A Díaz

  • Brain-derived neurotrophic factor and neurotrophin-3 support the survival and neuritogenesis response of developing cochleovestibular ganglion neurons

    Matias A. Avila;Isabel Varela-Nieto;Guillermo Romero;Jose M. Mato

  • Melanin precursors prevent premature age-related and noise-induced hearing loss in albino mice.

    Silvia Murillo-Cuesta;Julio Contreras;Julio Contreras;Esther Zurita;Rafael Cediel;Rafael Cediel

  • Cell signalling by inositol phosphoglycans from different species.

    Isabel Varela-Nieto;Yolanda León;Hugo N. Caro

  • RNA Microarray Analysis in Prenatal Mouse Cochlea Reveals Novel IGF-I Target Genes: Implication of MEF2 and FOXM1 Transcription Factors

    Hortensia Sanchez-Calderon;Hortensia Sanchez-Calderon;Lourdes Rodriguez-de la Rosa;Lourdes Rodriguez-de la Rosa;Marta Milo;Jose G. Pichel

  • Expression and function of phospholipase A2 in brain

    Marı́a A Balboa;Isabel Varela-Nieto;Karin Killermann Lucas;Edward A Dennis

  • Spatial and temporal segregation of auditory and vestibular neurons in the otic placode.

    Donald Bell;Andrea Streit;Itziar Gorospe;Isabel Varela-Nieto

  • Behavioral phenotype of maLPA1-null mice: increased anxiety-like behavior and spatial memory deficits.

    L. J. Santin;A. Bilbao;C. Pedraza;E. Matas-Rico

  • Insulin-like growth factor-I regulates cell proliferation in the developing inner ear, activating glycosyl-phosphatidylinositol hydrolysis and Fos expression.

    Y León;E Vazquez;C Sanz;J A Vega

  • Acidic sphingomyelinase downregulates the liver-specific methionine adenosyltransferase 1A, contributing to tumor necrosis factor-induced lethal hepatitis.

    Montserrat Marí;Anna Colell;Albert Morales;Covadonga Pañeda

  • Insulin-like growth factor 1 is required for survival of transit-amplifying neuroblasts and differentiation of otic neurons.

    G Camarero;Y Leon;I Gorospe;F De Pablo

  • Diabetes and the Role of Inositol-Containing Lipids in Insulin Signaling

    David R Jones;Isabel Varela-Nieto

  • Isolation and partial characterisation of insulin-mimetic inositol phosphoglycans from human liver.

    H.N. Caro;S. Kunjara;T.W. Rademacher;Y. León

Frequent Co-Authors

Lluís Montoliu
Lluís Montoliu Spanish National Research Council
Beth Levine
Beth Levine The University of Texas Southwestern Medical Center
Joaquín Dopazo
Joaquín Dopazo Institute of Biomedicine of Seville

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