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Immunology
Korea
2022

D-Index & Metrics

Immunology

D-Index
87
Citations
31677
World Ranking
1205
National Ranking
1

Medicine

D-Index
87
Citations
31677
World Ranking
13542
National Ranking
45

Research.com Recognitions

  • 2022 - Research.com Immunology in Korea Leader Award
  • 2007 - Ho-Am Prize in Medicine, Samsung Foundation

Overview

Charles D. Surh was affiliated with the Pohang University of Science and Technology in South Korea. Their research contributions spanned immunology and microbiology, with a substantial focus on immunology as well as intersections with biochemistry, genetics, and molecular biology.

Their work concentrated on several main topics within immune cell function and interaction, including:

  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • Immunotherapy and Immune Responses
  • Escherichia coli research studies
  • Cytomegalovirus and herpesvirus research
  • Retinoids in leukemia and cellular processes
  • Immune cells in cancer

Subfields of study included immunology, biotechnology, endocrinology, epidemiology, and molecular biology. This reflected a multidisciplinary approach to investigating immune mechanisms and their broader biological contexts.

Charles D. Surh authored multiple papers, notable among them:

  • "Epithelial HVEM maintains intraepithelial T cell survival and contributes to host protection," 2022, published in Science Immunology
  • "Dietary Glucose Consumption Promotes RALDH Activity in Small Intestinal CD103+CD11b+ Dendritic Cells," 2020, published in Frontiers in Immunology
  • "The antitumor effect induced by an IL-2 'no-alpha' mutein depends on changes in the CD8+ T lymphocyte/Treg cell balance," 2022, published in Frontiers in Immunology
  • "A blend of broadly-reactive and pathogen-selected Vγ4 Vδ1 T cell receptors confer broad bacterial reactivity of resident memory γδ T cells," 2021, published in Mucosal Immunology
  • "Listeria monocytogenes Establishes Commensalism in Germ-Free Mice Through the Reversible Downregulation of Virulence Gene Expression," 2021, published in Frontiers in Immunology

Several frequent co-authors collaborated with Surh, including:

  • Kwang Soon Kim
  • Kyungjin Cho
  • Masumi Takahashi
  • Julie A. Bettke
  • Oleksandr Gorbatsevych

The scientist published predominantly in journals such as Frontiers in Immunology, The Journal of Immunology, Science Immunology, Mucosal Immunology, and also contributed to bioRxiv (Cold Spring Harbor Laboratory).

Throughout their career, Charles D. Surh received recognition including the Ho-Am Prize in Medicine awarded by the Samsung Foundation in 2007.

Best Publications

  • Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells

    Susan M Kaech;Joyce T Tan;E John Wherry;Bogumila T Konieczny

  • Homeostasis of naive and memory T cells.

    Charles D. Surh;Jonathan Sprent

  • T-cell apoptosis detected in situ during positive and negative selection in the thymus

    Charles D. Surh;Jonathan Sprent

  • Removal of homeostatic cytokine sinks by lymphodepletion enhances the efficacy of adoptively transferred tumor-specific CD8+ T cells

    Luca Gattinoni;Steven E. Finkelstein;Christopher A. Klebanoff;Christopher A. Klebanoff;Paul A. Antony

  • IL-7 is critical for homeostatic proliferation and survival of naïve T cells

    Joyce T. Tan;Eric Dudl;Eric LeRoy;Richard Murray

  • Selective stimulation of T cell subsets with antibody-cytokine immune complexes

    Onur Boyman;Marek Kovar;Marek Kovar;Mark P. Rubinstein;Mark P. Rubinstein;Charles D. Surh;Charles D. Surh

  • Interleukin (IL)-15 and IL-7 jointly regulate homeostatic proliferation of memory phenotype CD8+ cells but are not required for memory phenotype CD4+ cells.

    Joyce T. Tan;Bettina Ernst;William C. Kieper;Eric M. Leroy

  • The Peptide Ligands Mediating Positive Selection in the Thymus Control T Cell Survival and Homeostatic Proliferation in the Periphery

    Bettina Ernst;Dong-Sup Lee;Jennifer M Chang;Jonathan Sprent

  • Interleukin 7 Regulates the Survival and Generation of Memory CD4 Cells

    Robyn M. Kondrack;Judith Harbertson;Joyce T. Tan;Meghan E. McBreen

  • Normal T cell homeostasis: the conversion of naive cells into memory-phenotype cells

    Jonathan Sprent;Charles D Surh;Charles D Surh

  • In vivo expansion of T reg cells with IL-2–mAb complexes: induction of resistance to EAE and long-term acceptance of islet allografts without immunosuppression

    Kylie E. Webster;Stacey Walters;Rachel E. Kohler;Tomas Mrkvan

  • Dietary antigens limit mucosal immunity by inducing regulatory T cells in the small intestine

    Kwang Soon Kim;Sung Wook Hong;Daehee Han;Jaeu Yi

  • T Cell Memory

    Unknown

  • Interleukin 15 Controls both Proliferation and Survival of a Subset of Memory-Phenotype CD8+ T Cells

    Adam D. Judge;Xiaohong Zhang;Hideki Fujii;Charles D. Surh

  • NKT cells derive from double-positive thymocytes that are positively selected by CD1d

    Laurent Gapin;Jennifer L. Matsuda;Jennifer L. Matsuda;Charles D. Surh;Mitchell Kronenberg;Mitchell Kronenberg

  • Converting IL-15 to a superagonist by binding to soluble IL-15Rα

    Mark P. Rubinstein;Marek Kovar;Jared F. Purton;Jae-Ho Cho

  • Generation and maintenance of memory CD4(+) T Cells.

    Jonathan Sprent;Charles D Surh

  • Homeostasis of V alpha 14i NKT cells.

    Jennifer L. Matsuda;Laurent Gapin;Stéphane Sidobre;William C. Kieper

  • Homeostatic T Cell Proliferation How Far Can T Cells Be Activated to Self-Ligands?

    Charles D. Surh;Jonathan Sprent

  • Cytokines and T-cell homeostasis.

    Onur Boyman;Jared F Purton;Charles D Surh;Jonathan Sprent

  • Antigen presentation and T cell development in H2-M-deficient mice.

    Wai-Ping Fung-Leung;Charles D. Surh;Monika Liljedahl;Jesse Pang

Frequent Co-Authors

Jonathan Sprent
Jonathan Sprent Garvan Institute of Medical Research
Onur Boyman
Onur Boyman University of Zurich
Ross L. Coppel
Ross L. Coppel Monash University
Per A. Peterson
Per A. Peterson Scripps Research Institute
Sin-Hyeog Im
Sin-Hyeog Im Pohang University of Science and Technology
M. Eric Gershwin
M. Eric Gershwin University of California, Davis
Laurent Gapin
Laurent Gapin University of Colorado Anschutz Medical Campus
Mitchell Kronenberg
Mitchell Kronenberg University of California, San Diego
Aftab A. Ansari
Aftab A. Ansari University of California, Davis
Young Chul Sung
Young Chul Sung Pohang University of Science and Technology

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