D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Immunology D-index 53 Citations 17,500 82 World Ranking 2428 National Ranking 144

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Immune system
  • Cancer

Luca Gattinoni mainly focuses on Immunology, Cytotoxic T cell, IL-2 receptor, CD8 and T cell. His work in Immunology tackles topics such as Cancer which are related to areas like Lymphocyte subsets and Transplantation. His IL-2 receptor research incorporates elements of Interleukin 21 and Cell biology.

His work deals with themes such as Interleukin 2 and Cancer research, which intersect with Interleukin 21. His biological study focuses on Antigen-presenting cell. The concepts of his Adoptive cell transfer study are interwoven with issues in Cell culture and Antigen.

His most cited work include:

  • A human memory T cell subset with stem cell-like properties (1070 citations)
  • Removal of homeostatic cytokine sinks by lymphodepletion enhances the efficacy of adoptively transferred tumor-specific CD8+ T cells (772 citations)
  • Adoptive immunotherapy for cancer: building on success (754 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of study are Immunology, Cytotoxic T cell, CD8, T cell and Cell biology. His Immunology study frequently draws parallels with other fields, such as Cancer research. His Cytotoxic T cell research integrates issues from Cytokine and Cellular differentiation.

In his research on the topic of CD8, Transcription factor, Regulator and Immunity is strongly related with Effector. His T cell research is multidisciplinary, relying on both Stem cell and Cancer immunotherapy. His studies in Cell biology integrate themes in fields like Transcriptome, Epigenetics and Anaerobic glycolysis.

He most often published in these fields:

  • Immunology (56.00%)
  • Cytotoxic T cell (48.00%)
  • CD8 (44.00%)

What were the highlights of his more recent work (between 2015-2021)?

  • CD8 (44.00%)
  • T cell (39.33%)
  • Cell biology (32.00%)

In recent papers he was focusing on the following fields of study:

The scientist’s investigation covers issues in CD8, T cell, Cell biology, Cytotoxic T cell and Stem cell. His CD8 study combines topics in areas such as Progenitor cell, Ex vivo, Adoptive cell transfer and Effector. T cell is a subfield of Immunology that Luca Gattinoni tackles.

His Cell biology research is multidisciplinary, incorporating perspectives in Regulation of gene expression, Transcriptome, Immunophenotyping and Memory T cell. His research in Cytotoxic T cell intersects with topics in Transcription factor, Epigenetics and T-cell receptor. Luca Gattinoni has researched Stem cell in several fields, including Cell culture and Immunotherapy.

Between 2015 and 2021, his most popular works were:

  • Mitochondrial Membrane Potential Identifies Cells with Enhanced Stemness for Cellular Therapy (176 citations)
  • The TCF1-Bcl6 axis counteracts type I interferon to repress exhaustion and maintain T cell stemness. (173 citations)
  • T memory stem cells in health and disease (163 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Immune system
  • Cancer

Luca Gattinoni mainly investigates CD8, Stem cell, Adoptive cell transfer, Cell biology and T cell. His biological study spans a wide range of topics, including Cytotoxic T cell and Effector. His Adoptive cell transfer study incorporates themes from Chimeric antigen receptor, Immunotherapy, Disease and Neuroscience.

His Cell biology research incorporates themes from Regulation of gene expression and Transcriptome. His T cell study which covers Cancer immunotherapy that intersects with Fas ligand and Apoptosis. Luca Gattinoni interconnects Progenitor cell and Hematopoietic stem cell transplantation in the investigation of issues within Immunology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Adoptive immunotherapy for cancer: building on success

Luca Gattinoni;Daniel J. Powell;Steven A. Rosenberg;Nicholas P. Restifo.
Nature Reviews Immunology (2006)

1463 Citations

A human memory T cell subset with stem cell-like properties

Luca Gattinoni;Enrico Lugli;Yun Ji;Zoltan Pos.
Nature Medicine (2011)

1252 Citations

Removal of homeostatic cytokine sinks by lymphodepletion enhances the efficacy of adoptively transferred tumor-specific CD8+ T cells

Luca Gattinoni;Steven E. Finkelstein;Christopher A. Klebanoff;Christopher A. Klebanoff;Paul A. Antony.
Journal of Experimental Medicine (2005)

1000 Citations

Acquisition of full effector function in vitro paradoxically impairs the in vivo antitumor efficacy of adoptively transferred CD8+ T cells

Luca Gattinoni;Christopher A. Klebanoff;Christopher A. Klebanoff;Douglas C. Palmer;Claudia Wrzesinski.
Journal of Clinical Investigation (2005)

986 Citations

Central memory self/tumor-reactive CD8+ T cells confer superior antitumor immunity compared with effector memory T cells

Christopher A. Klebanoff;Luca Gattinoni;Parizad Torabi-Parizi;Keith Kerstann.
Proceedings of the National Academy of Sciences of the United States of America (2005)

951 Citations

Tumor-specific Th17-polarized cells eradicate large established melanoma

Pawel Muranski;Andrea Boni;Paul A. Antony;Lydie Cassard.
Blood (2008)

871 Citations

Wnt signaling arrests effector T cell differentiation and generates CD8+ memory stem cells

Luca Gattinoni;Xiao-Song Zhong;Douglas C Palmer;Yun Ji.
Nature Medicine (2009)

800 Citations

IL-15 enhances the in vivo antitumor activity of tumor-reactive CD8+ T Cells

Christopher A. Klebanoff;Steven E. Finkelstein;Deborah R. Surman;Michael K. Lichtman;Michael K. Lichtman.
Proceedings of the National Academy of Sciences of the United States of America (2004)

582 Citations

Inhibiting glycolytic metabolism enhances CD8+ T cell memory and antitumor function

Madhusudhanan Sukumar;Jie Liu;Yun Ji;Murugan Subramanian.
Journal of Clinical Investigation (2013)

555 Citations

CD8+ T‐cell memory in tumor immunology and immunotherapy

Christopher A. Klebanoff;Luca Gattinoni;Nicholas P. Restifo.
Immunological Reviews (2006)

548 Citations

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