Luca Gattinoni mainly focuses on Immunology, Cytotoxic T cell, IL-2 receptor, CD8 and T cell. His work in Immunology tackles topics such as Cancer which are related to areas like Lymphocyte subsets and Transplantation. His IL-2 receptor research incorporates elements of Interleukin 21 and Cell biology.
His work deals with themes such as Interleukin 2 and Cancer research, which intersect with Interleukin 21. His biological study focuses on Antigen-presenting cell. The concepts of his Adoptive cell transfer study are interwoven with issues in Cell culture and Antigen.
His primary areas of study are Immunology, Cytotoxic T cell, CD8, T cell and Cell biology. His Immunology study frequently draws parallels with other fields, such as Cancer research. His Cytotoxic T cell research integrates issues from Cytokine and Cellular differentiation.
In his research on the topic of CD8, Transcription factor, Regulator and Immunity is strongly related with Effector. His T cell research is multidisciplinary, relying on both Stem cell and Cancer immunotherapy. His studies in Cell biology integrate themes in fields like Transcriptome, Epigenetics and Anaerobic glycolysis.
The scientist’s investigation covers issues in CD8, T cell, Cell biology, Cytotoxic T cell and Stem cell. His CD8 study combines topics in areas such as Progenitor cell, Ex vivo, Adoptive cell transfer and Effector. T cell is a subfield of Immunology that Luca Gattinoni tackles.
His Cell biology research is multidisciplinary, incorporating perspectives in Regulation of gene expression, Transcriptome, Immunophenotyping and Memory T cell. His research in Cytotoxic T cell intersects with topics in Transcription factor, Epigenetics and T-cell receptor. Luca Gattinoni has researched Stem cell in several fields, including Cell culture and Immunotherapy.
Luca Gattinoni mainly investigates CD8, Stem cell, Adoptive cell transfer, Cell biology and T cell. His biological study spans a wide range of topics, including Cytotoxic T cell and Effector. His Adoptive cell transfer study incorporates themes from Chimeric antigen receptor, Immunotherapy, Disease and Neuroscience.
His Cell biology research incorporates themes from Regulation of gene expression and Transcriptome. His T cell study which covers Cancer immunotherapy that intersects with Fas ligand and Apoptosis. Luca Gattinoni interconnects Progenitor cell and Hematopoietic stem cell transplantation in the investigation of issues within Immunology.
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Adoptive immunotherapy for cancer: building on success
Luca Gattinoni;Daniel J. Powell;Steven A. Rosenberg;Nicholas P. Restifo.
Nature Reviews Immunology (2006)
A human memory T cell subset with stem cell-like properties
Luca Gattinoni;Enrico Lugli;Yun Ji;Zoltan Pos.
Nature Medicine (2011)
Removal of homeostatic cytokine sinks by lymphodepletion enhances the efficacy of adoptively transferred tumor-specific CD8+ T cells
Luca Gattinoni;Steven E. Finkelstein;Christopher A. Klebanoff;Christopher A. Klebanoff;Paul A. Antony.
Journal of Experimental Medicine (2005)
Acquisition of full effector function in vitro paradoxically impairs the in vivo antitumor efficacy of adoptively transferred CD8+ T cells
Luca Gattinoni;Christopher A. Klebanoff;Christopher A. Klebanoff;Douglas C. Palmer;Claudia Wrzesinski.
Journal of Clinical Investigation (2005)
Central memory self/tumor-reactive CD8+ T cells confer superior antitumor immunity compared with effector memory T cells
Christopher A. Klebanoff;Luca Gattinoni;Parizad Torabi-Parizi;Keith Kerstann.
Proceedings of the National Academy of Sciences of the United States of America (2005)
Tumor-specific Th17-polarized cells eradicate large established melanoma
Pawel Muranski;Andrea Boni;Paul A. Antony;Lydie Cassard.
Wnt signaling arrests effector T cell differentiation and generates CD8+ memory stem cells
Luca Gattinoni;Xiao-Song Zhong;Douglas C Palmer;Yun Ji.
Nature Medicine (2009)
IL-15 enhances the in vivo antitumor activity of tumor-reactive CD8+ T Cells
Christopher A. Klebanoff;Steven E. Finkelstein;Deborah R. Surman;Michael K. Lichtman;Michael K. Lichtman.
Proceedings of the National Academy of Sciences of the United States of America (2004)
Inhibiting glycolytic metabolism enhances CD8+ T cell memory and antitumor function
Madhusudhanan Sukumar;Jie Liu;Yun Ji;Murugan Subramanian.
Journal of Clinical Investigation (2013)
CD8+ T‐cell memory in tumor immunology and immunotherapy
Christopher A. Klebanoff;Luca Gattinoni;Nicholas P. Restifo.
Immunological Reviews (2006)
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