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Chrystal M. Paulos

Chrystal M. Paulos

D-Index & Metrics

Immunology

D-Index
49
Citations
14752
World Ranking
4297
National Ranking
1953

Overview

Chrystal M. Paulos is affiliated with Emory University in the United States. Their research is primarily situated in the fields of Medicine and Immunology and Microbiology, with a particular focus on Oncology and Immunology within these broader disciplines.

The scientist's work encompasses several subfields, including Oncology, Immunology, Molecular Biology, Pulmonary and Respiratory Medicine, and Surgery. Their research topics reveal a concentration on Cancer Immunotherapy and Biomarkers, CAR-T Cell Therapy Research, Immunotherapy and Immune Responses, Immune Cell Function and Interaction, T-cell and B-cell Immunology, Pancreatic and Hepatic Oncology Research, and Peptidase Inhibition and Analysis.

Frequent publication venues for Chrystal M. Paulos include Regular and Young Investigator Award Abstracts, Cancer Research, bioRxiv (Cold Spring Harbor Laboratory), The Journal of Immunology, and Journal for ImmunoTherapy of Cancer.

Notable recent papers authored or co-authored by Paulos include:

  • Fundamentals of T Cell Metabolism and Strategies to Enhance Cancer Immunotherapy, 2021, Frontiers in Immunology
  • Neoadjuvant presurgical PD-1 inhibition in oral cavity squamous cell carcinoma, 2021, Cell Reports Medicine
  • Statin drugs enhance responses to immune checkpoint blockade in head and neck cancer models, 2023, Journal for ImmunoTherapy of Cancer
  • Ex vivo blockade of PI3K gamma or delta signaling enhances the antitumor potency of adoptively transferred CD8 + T cells, 2020, European Journal of Immunology
  • RNA binding protein PCBP1 is an intracellular immune checkpoint for shaping T cell responses in cancer immunity, 2020, Science Advances

Collaborators frequently working with Chrystal M. Paulos include Megan M. Wyatt, Hannah M. Knochelmann, Gregory B. Lesinski, Guillermo O. Rangel Rivera, and Aubrey S. Smith.

Best Publications

  • A human memory T cell subset with stem cell-like properties

    Luca Gattinoni;Enrico Lugli;Yun Ji;Zoltan Pos

  • Wnt signaling arrests effector T cell differentiation and generates CD8+ memory stem cells

    Luca Gattinoni;Xiao-Song Zhong;Douglas C Palmer;Yun Ji

  • Tumor-specific Th17-polarized cells eradicate large established melanoma

    Pawel Muranski;Andrea Boni;Paul A. Antony;Lydie Cassard

  • Microbial translocation augments the function of adoptively transferred self/tumor-specific CD8 + T cells via TLR4 signaling

    Chrystal M. Paulos;Claudia Wrzesinski;Andrew Kaiser;Christian S. Hinrichs

  • When worlds collide: Th17 and Treg cells in cancer and autoimmunity.

    Hannah M. Knochelmann;Connor J. Dwyer;Stefanie R. Bailey;Sierra M. Amaya

  • Multiple injections of electroporated autologous T cells expressing a chimeric antigen receptor mediate regression of human disseminated tumor

    Yangbing Zhao;Edmund Moon;Carmine Carpenito;Chrystal M. Paulos

  • IL-2 and IL-21 confer opposing differentiation programs to CD8+ T cells for adoptive immunotherapy.

    Christian S. Hinrichs;Rosanne Spolski;Chrystal M. Paulos;Luca Gattinoni

  • Folate receptor-mediated targeting of therapeutic and imaging agents to activated macrophages in rheumatoid arthritis

    Chrystal M. Paulos;Mary Jo Turk;Gert J. Breur;Philip S. Low

  • Th17 Cells in Cancer: The Ultimate Identity Crisis

    Stefanie R. Bailey;Michelle H. Nelson;Richard A. Himes;Zihai Li

  • Identification of Chimeric Antigen Receptors That Mediate Constitutive or Inducible Proliferation of T Cells

    Matthew J. Frigault;Jihyun Lee;Maria Ciocca Basil;Carmine Carpenito

  • Increased intensity lymphodepletion enhances tumor treatment efficacy of adoptively transferred tumor-specific T cells.

    Claudia Wrzesinski;Chrystal M. Paulos;Chrystal M. Paulos;Andrew Kaiser;Pawel Muranski

  • Resident memory T cells in the skin mediate durable immunity to melanoma.

    Brian T. Malik;Katelyn T. Byrne;Katelyn T. Byrne;Jennifer L. Vella;Peisheng Zhang

  • Platelets subvert T cell immunity against cancer via GARP-TGFβ axis.

    Saleh Rachidi;Alessandra Metelli;Brian Riesenberg;Bill X. Wu

  • Ligand Binding and Kinetics of Folate Receptor Recycling in Vivo: Impact on Receptor-Mediated Drug Delivery

    Chrystal M. Paulos;Joseph A. Reddy;Christopher P. Leamon;Mary Jo Turk

  • The inducible costimulator (ICOS) is critical for the development of human T(H)17 cells.

    Chrystal M. Paulos;Carmine Carpenito;Gabriela Plesa;Megan M. Suhoski

  • Folate‐targeted imaging of activated macrophages in rats with adjuvant‐induced arthritis

    Mary Jo Turk;Gert J. Breur;William R. Widmer;Chrystal M. Paulos

  • Type 17 CD8+ T cells display enhanced antitumor immunity.

    Christian S. Hinrichs;Andrew Kaiser;Chrystal M. Paulos;Lydie Cassard

  • Hematopoietic stem cells promote the expansion and function of adoptively transferred antitumor CD8+ T cells

    Claudia Wrzesinski;Chrystal M. Paulos;Luca Gattinoni;Douglas C. Palmer

  • CD38-NAD+Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response

    Shilpak Chatterjee;Anusara Daenthanasanmak;Paramita Chakraborty;Megan W. Wyatt

  • CAR T Cells in Solid Tumors: Blueprints for Building Effective Therapies.

    Hannah M. Knochelmann;Aubrey S. Smith;Connor J. Dwyer;Megan M. Wyatt

Frequent Co-Authors

Luca Gattinoni
Luca Gattinoni University of Regensburg
Nicholas P. Restifo
Nicholas P. Restifo National Institutes of Health
Zihai Li
Zihai Li The Ohio State University
Douglas C. Palmer
Douglas C. Palmer National Institutes of Health
Steven A. Rosenberg
Steven A. Rosenberg National Institutes of Health
Carl H. June
Carl H. June University of Pennsylvania
Michael I. Nishimura
Michael I. Nishimura Loyola University Chicago
Zhiya Yu
Zhiya Yu National Institutes of Health
Xue-Zhong Yu
Xue-Zhong Yu Medical College of Wisconsin
Philip S. Low
Philip S. Low Purdue University West Lafayette

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