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Microbiology

D-Index
54
Citations
11564
World Ranking
3939
National Ranking
1533

Overview

Michael I. Nishimura is a researcher affiliated with Loyola University Chicago in the United States. Their work spans several fields within biomedical science, with a strong focus on immunology, oncology, and molecular biology.

The main fields of study for Nishimura include Medicine, Biochemistry, Genetics and Molecular Biology, and Immunology and Microbiology. The subfields reflect these areas, with Immunology, Oncology, Molecular Biology, Cancer Research, and Physiology highlighted in their research portfolio.

The scientist's research covers a range of topics related to cancer and immune system function. Key areas of focus include CAR-T cell therapy research, immunotherapy and immune responses, T-cell and B-cell immunology, cancer genomics and diagnostics, cancer immunotherapy and biomarkers, glycosylation and glycoproteins research, as well as galectins and cancer biology.

Recent publications authored or co-authored by Nishimura span from 2020 to 2022. These include:

  • "Siglec-5 is an inhibitory immune checkpoint molecule for human T cells," 2022, Immunology
  • "Identification of human CD4 + T cell populations with distinct antitumor activity," 2020, Science Advances
  • "Endothelin-1-Mediated Drug Resistance in EGFR-Mutant Non-Small Cell Lung Carcinoma," 2020, Cancer Research
  • "Human CD36hi monocytes induce Foxp3+ CD25+ T cells with regulatory functions from CD4 and CD8 subsets," 2021, Immunology
  • "A class-mismatched TCR bypasses MHC restriction via an unorthodox but fully functional binding geometry," 2022, Nature Communications

The primary venues publishing Nishimura's work include the Journal of Clinical Oncology, Immunology, Science Advances, Cancer Research, and bioRxiv (Cold Spring Harbor Laboratory). These journals reflect the interdisciplinary nature of their research, combining clinical and molecular investigations.

Frequent collaborators working alongside Nishimura are Gina Scurti, Annika V. Dalheim, Stefan Barisic, Elena Cherkasova, and Long Chen, each contributing to multiple joint publications, indicating sustained research partnerships.

Best Publications

  • Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin–cyclophosphamide chemotherapy

    C. Marcela Diaz-Montero;Mohamed Labib Salem;Michael I. Nishimura;Elizabeth Garrett-Mayer

  • Cancer classification using the Immunoscore: a worldwide task force

    Jérôme Galon;Franck Pagès;Francesco M Marincola;Francesco M Marincola;Helen K Angell;Helen K Angell

  • Efficient Transfer of a Tumor Antigen-Reactive TCR to Human Peripheral Blood Lymphocytes Confers Anti-Tumor Reactivity

    Timothy M. Clay;Mary C. Custer;Jessica Sachs;Patrick Hwu

  • Adoptive transfer of cloned melanoma-reactive T lymphocytes for the treatment of patients with metastatic melanoma

    Mark E. Dudley;John Wunderlich;Michael I. Nishimura;David Yu

  • Tim-3 expression on PD-1+ HCV-specific human CTLs is associated with viral persistence, and its blockade restores hepatocyte-directed in vitro cytotoxicity

    Rachel H. McMahan;Lucy Golden-Mason;Michael I. Nishimura;Brian J. McMahon

  • Recognition of host immune activation by Pseudomonas aeruginosa

    Licheng Wu;Oscar Estrada;Olga Zaborina;Manjeet Bains

  • Increasing tumor antigen expression overcomes "ignorance" to solid tumors via crosspresentation by bone marrow-derived stromal cells.

    Michael T. Spiotto;Ping Yu;Donald A. Rowley;Michael I. Nishimura

  • CD38-NAD+Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response

    Shilpak Chatterjee;Anusara Daenthanasanmak;Paramita Chakraborty;Megan W. Wyatt

  • Identification of epitope mimics recognized by CTL reactive to the melanoma/melanocyte-derived peptide MART-1((27-35))

    Douglas J. Loftus;Chiara Castelli;Timothy M. Clay;Paola Squarcina

  • Biochemical Identification of a Mutated Human Melanoma Antigen Recognized by CD4+ T Cells

    Rembert Pieper;Robert E. Christian;Monica I. Gonzales;Michael I. Nishimura

  • Defining the critical hurdles in cancer immunotherapy

    Bernard A. Fox;Bernard A. Fox;Dolores J. Schendel;Lisa H. Butterfield;Steinar Aamdal

  • Human tumor-derived exosomes (TEX) regulate Treg functions via cell surface signaling rather than uptake mechanisms

    Laurent Muller;Patricia Simms;Chang-Sook Hong;Michael I. Nishimura

  • Reduced skin homing by functional Treg in vitiligo

    Jared Klarquist;Cecele J. Denman;Claudia Hernandez;Derek J. Wainwright

  • Human antigen-specific regulatory T cells generated by T cell receptor gene transfer.

    Todd M. Brusko;Richard C. Koya;Shirley Zhu;Michael R. Lee

  • Changes in the Fine Specificity of gp100(209–217)-Reactive T Cells in Patients Following Vaccination with a Peptide Modified at an HLA-A2.1 Anchor Residue

    Timothy M. Clay;Mary C. Custer;Mark D. McKee;Maria Parkhurst

  • Cloning and characterization of the genes encoding the murine homologues of the human melanoma antigens MART1 and gp100.

    Yifan Zhai;James C. Yang;Paul Spiess;Michael I. Nishimura

  • Simultaneous Generation of CD8+ and CD4+ Melanoma-Reactive T Cells by Retroviral-Mediated Transfer of a Single T-Cell Receptor

    Jeffrey J. Roszkowski;Gretchen E. Lyons;W. Martin Kast;Cassian Yee

  • Characterization of the functional specificity of a cloned T-cell receptor heterodimer recognizing the MART-1 melanoma antigen.

    David J. Cole;Daniel P. Weil;Joel Shilyansky;Mary Custer

  • Mutant HSP70 Reverses Autoimmune Depigmentation in Vitiligo

    Jeffrey A. Mosenson;Andrew Zloza;Andrew Zloza;John D. Nieland;Elizabeth Garrett-Mayer

  • Vaccination with poly(IC:LC) and peptide-pulsed autologous dendritic cells in patients with pancreatic cancer.

    Shikhar Mehrotra;Carolyn D. Britten;Steve Chin;Steve Chin;Elizabeth Garrett-Mayer

  • Identification of Epitope Mimics Recognized by CTL Reactive to the Melanoma/Melanocyte-derived Peptide

    Douglas J. Loftus;Chiara Castelli;Timothy M. Clayfi;Paola Squarcina

Frequent Co-Authors

Steven A. Rosenberg
Steven A. Rosenberg National Institutes of Health
Timothy M. Clay
Timothy M. Clay Duke University
Brian M. Baker
Brian M. Baker University of Notre Dame
Hugo R. Rosen
Hugo R. Rosen University of Southern California
Chrystal M. Paulos
Chrystal M. Paulos Emory University
Suzanne L. Topalian
Suzanne L. Topalian Johns Hopkins University
Bernard A. FoxEarle
Bernard A. FoxEarle Earle A. Chiles Research Institute
Yutaka Kawakami
Yutaka Kawakami International University Of Health And Welfare Atami Hospital
James Chih-Hsin Yang
James Chih-Hsin Yang National Taiwan University
W. Martin Kast
W. Martin Kast University of Southern California

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