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Immunology

D-Index
49
Citations
15718
World Ranking
4295
National Ranking
1952

Overview

Laurent Gapin is affiliated with the University of Colorado Anschutz Medical Campus in the United States. Their research primarily focuses on immunology and microbiology, with significant contributions spanning medicine as well.

Their work is concentrated within several subfields including immunology, oncology, molecular biology, public health, environmental and occupational health, and microbiology. The main research topics they address involve immune cell function and interaction, T-cell and B-cell immunology, immunotherapy and immune responses, CAR-T cell therapy research, IL-33, ST2, and ILC pathways, single-cell and spatial transcriptomics, and neonatal and maternal infections.

Laurent Gapin has published numerous papers in various scientific venues, including:

  • Thymic iNKT single cell analyses unmask the common developmental program of mouse innate T cells (2020, Nature Communications)
  • MAIT Cells: Partners or Enemies in Cancer Immunotherapy? (2021, Cancers)
  • Circulating CD8 + mucosal-associated invariant T cells correlate with improved treatment responses and overall survival in anti-PD-1-treated melanoma patients (2022, Clinical & Translational Immunology)
  • Current insights in mouse iNKT and MAIT cell development using single cell transcriptomics data (2022, Seminars in Immunology)
  • Type II Natural Killer T Cells Contribute to Protection Against Systemic Methicillin-Resistant Staphylococcus aureus Infection (2020, Frontiers in Immunology)

Frequent publication venues where Laurent Gapin's research appears include:

  • bioRxiv (Cold Spring Harbor Laboratory) with 7 publications
  • The Journal of Immunology with 3 publications
  • Nature Communications
  • Cancers
  • Clinical & Translational Immunology

Collaborations have been established with several frequent coauthors, among them:

  • Liyen Loh (10 coauthored works)
  • Tonya M. Brunetti (7 coauthored works)
  • Andrea Spengler (7 coauthored works)
  • Martin D. McCarter (6 coauthored works)
  • Richard P. Tobin (6 coauthored works)

Best Publications

  • Inflammation directs memory precursor and short-lived effector CD8(+) T cell fates via the graded expression of T-bet transcription factor.

    Nikhil S. Joshi;Weiguo Cui;Anmol Chandele;Heung Kyu Lee

  • Effector and memory CD8 + T cell fate coupled by T-bet and eomesodermin

    Andrew M Intlekofer;Naofumi Takemoto;E John Wherry;E John Wherry;Sarah A Longworth

  • Tracking the response of natural killer T cells to a glycolipid antigen using CD1d tetramers.

    Jennifer L. Matsuda;Jennifer L. Matsuda;Olga V. Naidenko;Laurent Gapin;Toshinori Nakayama

  • The unconventional lifestyle of NKT cells

    Mitchell Kronenberg;Laurent Gapin

  • T-bet Regulates the Terminal Maturation and Homeostasis of NK and Vα14i NKT Cells

    Michael J Townsend;Amy S Weinmann;Jennifer L Matsuda;Rachelle Salomon

  • Constitutive Cytokine mRNAs Mark Natural Killer (NK) and NK T Cells Poised for Rapid Effector Function

    Daniel B. Stetson;Markus Mohrs;R. Lee Reinhardt;Jody L. Baron

  • Recognition of CD1d-restricted antigens by natural killer T cells

    Jamie Rossjohn;Daniel G Pellicci;Onisha G Patel;Laurent Gapin

  • NKT cells derive from double-positive thymocytes that are positively selected by CD1d

    Laurent Gapin;Jennifer L. Matsuda;Jennifer L. Matsuda;Charles D. Surh;Mitchell Kronenberg;Mitchell Kronenberg

  • CD1d-restricted iNKT cells, the ‘Swiss-Army knife’ of the immune system

    Jennifer L Matsuda;Thierry Mallevaey;James Scott-Browne;Laurent Gapin

  • Homeostasis of V alpha 14i NKT cells.

    Jennifer L. Matsuda;Laurent Gapin;Stéphane Sidobre;William C. Kieper

  • Overexpression of Interleukin (IL)-7 Leads to IL-15–independent Generation of Memory Phenotype CD8+ T Cells

    William C. Kieper;Joyce T. Tan;Brea Bondi-Boyd;Laurent Gapin

  • Evolutionarily conserved amino acids that control TCR-MHC interaction.

    Philippa Marrack;James P. Scott-Browne;Shaodong Dai;Laurent Gapin

  • Mouse Vα14i natural killer T cells are resistant to cytokine polarization in vivo

    Jennifer L. Matsuda;Laurent Gapin;Jody L. Baron;Stéphane Sidobre

  • Differential Recognition of CD1d-α-Galactosyl Ceramide by the Vβ8.2 and Vβ7 Semi-invariant NKT T Cell Receptors

    Daniel G Pellicci;Onisha Patel;Lars Kjer-Nielsen;Siew Siew Pang

  • Precursors of Functional MHC Class I- or Class II-Restricted CD8αα+ T Cells Are Positively Selected in the Thymus by Agonist Self-Peptides

    Andrew J Leishman;Laurent Gapin;Myriam Capone;Ed Palmer

  • T-bet concomitantly controls migration, survival, and effector functions during the development of Vα14i NKT cells

    Jennifer L. Matsuda;Qianjun Zhang;Qianjun Zhang;Rachel Ndonye;Rachel Ndonye;Stewart K. Richardson;Stewart K. Richardson

  • CD1d-expressing Dendritic Cells but Not Thymic Epithelial Cells Can Mediate Negative Selection of NKT Cells

    Taehoon Chun;Michael J. Page;Laurent Gapin;Jennifer L. Matsuda

  • Germline-encoded recognition of diverse glycolipids by natural killer T cells.

    James P Scott-Browne;Jennifer L Matsuda;Thierry Mallevaey;Janice White

  • Germline-encoded amino acids in the αβ T-cell receptor control thymic selection

    James P. Scott-Browne;Janice White;John W. Kappler;Laurent Gapin

  • CD8α+ Dendritic Cell Trans Presentation of IL-15 to Naive CD8+ T Cells Produces Antigen-Inexperienced T Cells in the Periphery with Memory Phenotype and Function

    Tomasz Sosinowski;Jason T. White;Eric W. Cross;Catherine Haluszczak

Frequent Co-Authors

Philippa Marrack
Philippa Marrack National Jewish Health
John W. Kappler
John W. Kappler National Jewish Health
Jamie Rossjohn
Jamie Rossjohn Monash University
Mitchell Kronenberg
Mitchell Kronenberg University of California, San Diego
Dale I. Godfrey
Dale I. Godfrey University of Melbourne
James McCluskey
James McCluskey University of Melbourne
Daniel G. Pellicci
Daniel G. Pellicci University of Melbourne
Janice White
Janice White Howard Hughes Medical Institute
Philippe Kourilsky
Philippe Kourilsky Collège de France
Lars Kjer-Nielsen
Lars Kjer-Nielsen University of Melbourne

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