D-Index & Metrics Best Publications

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Immunology D-index 85 Citations 23,070 281 World Ranking 520 National Ranking 20
Medicine D-index 87 Citations 24,362 304 World Ranking 6775 National Ranking 238

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Immune system
  • Antigen

James McCluskey focuses on T-cell receptor, T cell, Antigen, Major histocompatibility complex and Immunology. His T-cell receptor research is multidisciplinary, incorporating elements of Receptor, CTL*, T cell subset and Cell biology. His work carried out in the field of T cell brings together such families of science as Molecular biology and RAR-related orphan receptor gamma.

His Major histocompatibility complex research includes elements of Epitope, Cytotoxic T cell, Antigen presentation and CD8. His Antigen presentation research integrates issues from HLA-B Antigens, Human leukocyte antigen, MHC class I and Computational biology. His research investigates the link between Immunology and topics such as Virology that cross with problems in Tumor antigen and CD40.

His most cited work include:

  • MR1 presents microbial vitamin B metabolites to MAIT cells (790 citations)
  • Eea1, An Early Endosome-Associated Protein - Eea1 Is a Conserved Alpha-Helical Peripheral Membrane-Protein Flanked by Cysteine Fingers and Contains a Calmodulin-Binding Iq Motif (634 citations)
  • More than one reason to rethink the use of peptides in vaccine design (527 citations)

What are the main themes of his work throughout his whole career to date?

James McCluskey mainly investigates Immunology, Antigen, T cell, Major histocompatibility complex and T-cell receptor. His Immunology study combines topics in areas such as Cytotoxic T cell and Virology. His Antigen research is multidisciplinary, relying on both Molecular biology, Biochemistry and Antigen presentation.

His Major histocompatibility complex research is within the category of Genetics. James McCluskey focuses mostly in the field of T-cell receptor, narrowing it down to topics relating to Cell biology and, in certain cases, Antigen processing and Cell. In the field of Human leukocyte antigen, his study on HLA-B Antigens and HLA-B overlaps with subjects such as Abacavir.

He most often published in these fields:

  • Immunology (39.54%)
  • Antigen (29.37%)
  • T cell (27.64%)

What were the highlights of his more recent work (between 2013-2021)?

  • T cell (27.64%)
  • Immunology (39.54%)
  • Mucosal associated invariant T cell (10.36%)

In recent papers he was focusing on the following fields of study:

James McCluskey spends much of his time researching T cell, Immunology, Mucosal associated invariant T cell, Antigen and T-cell receptor. His T cell study combines topics from a wide range of disciplines, such as Molecular biology, Human leukocyte antigen and Major histocompatibility complex. The various areas that James McCluskey examines in his Immunology study include Cytotoxic T cell and Downregulation and upregulation.

As part of one scientific family, James McCluskey deals mainly with the area of Antigen, narrowing it down to issues related to the Antigen presentation, and often CD1. His studies in T-cell receptor integrate themes in fields like Epitope, MHC class I, CD3 and Cell biology. His research integrates issues of Antigen processing, MHC restriction and Cellular differentiation in his study of Cell biology.

Between 2013 and 2021, his most popular works were:

  • T-cell activation by transitory neo-antigens derived from distinct microbial pathways (437 citations)
  • The burgeoning family of unconventional T cells. (391 citations)
  • T Cell Antigen Receptor Recognition of Antigen-Presenting Molecules (367 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Immune system
  • Internal medicine

James McCluskey mostly deals with Mucosal associated invariant T cell, T cell, Antigen, T-cell receptor and Immunology. He has researched T cell in several fields, including Molecular biology, RAR-related orphan receptor gamma and Cell biology. His research in Antigen intersects with topics in Receptor, Cell, Biochemistry and Cell culture.

His T-cell receptor research includes themes of MHC class I, CD8, Major histocompatibility complex and Antigen presentation. His biological study spans a wide range of topics, including Plasma protein binding and Binding site. His studies deal with areas such as Cytotoxic T cell and Transplantation as well as Immunology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Eea1, An Early Endosome-Associated Protein - Eea1 Is a Conserved Alpha-Helical Peripheral Membrane-Protein Flanked by Cysteine Fingers and Contains a Calmodulin-Binding Iq Motif

Fi Tjen Mu;Judy M. Callaghan;Olivia Steele-Mortimer;Harald Stenmark.
Journal of Biological Chemistry (1995)

808 Citations

MR1 presents microbial vitamin B metabolites to MAIT cells

Lars Kjer-Nielsen;Onisha G Patel;Alexandra J Corbett;Jerome Le Nours;Jerome Le Nours.
Nature (2012)

807 Citations

More than one reason to rethink the use of peptides in vaccine design

Anthony W. Purcell;James McCluskey;Jamie Rossjohn.
Nature Reviews Drug Discovery (2007)

686 Citations

Immune self-reactivity triggered by drug-modified HLA-peptide repertoire

Patricia T Illing;Julian P Vivian;Nadine Lee Dudek;Lyudmila Kostenko.
Nature (2012)

605 Citations

CD1d–lipid-antigen recognition by the semi-invariant NKT T-cell receptor

Natalie Borg;Kwok Soon Wun;Lars Kjer-Nielsen;Matthew Charles James Wilce.
Nature (2007)

584 Citations

Predisposition to abacavir hypersensitivity conferred by HLA-B*5701 and a haplotypic Hsp70-Hom variant

Annalise M. Martin;David Nolan;Silvana Gaudieri;Silvana Gaudieri;Coral Ann Almeida.
Proceedings of the National Academy of Sciences of the United States of America (2004)

519 Citations

T-cell activation by transitory neo-antigens derived from distinct microbial pathways

Alexandra Corbett;Sidonia B G Eckle;Richard William Birkinshaw;Ligong Liu.
Nature (2014)

502 Citations

T Cell Antigen Receptor Recognition of Antigen-Presenting Molecules

Jamie Rossjohn;Stephanie Gras;John James Miles;Stephen J. Turner.
Annual Review of Immunology (2015)

426 Citations

Comprehensive, Quantitative Mapping of T Cell Epitopes in Gluten in Celiac Disease

Jason A Tye-Din;Jessica A Stewart;James A Dromey;Tim Beissbarth.
Science Translational Medicine (2010)

408 Citations

Optimization of the MHC Class I Peptide Cargo Is Dependent on Tapasin

Anthony P Williams;Anthony P Williams;Chen Au Peh;Anthony W Purcell;James McCluskey.
Immunity (2002)

394 Citations

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