World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
105
Citations
38929
World Ranking
594
National Ranking
18

Medicine

D-Index
105
Citations
39143
World Ranking
6791
National Ranking
193

Overview

James McCluskey is affiliated with the University of Melbourne in Australia. Their research spans several areas within immunology and microbiology, with a focus on immune cell function and interaction. The scientist has published extensively in related fields, contributing to the understanding of T-cell and B-cell immunology, immunotherapy and immune responses, and other specialized topics.

The main fields of study in McCluskey's work include:

  • Immunology and Microbiology
  • Medicine

Their contributions also extend across various subfields such as:

  • Immunology
  • Epidemiology
  • Molecular Biology
  • Oncology
  • Genetics

Key topics addressed in their research are:

  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • Immunotherapy and Immune Responses
  • Cytomegalovirus and herpesvirus research
  • CAR-T cell therapy research
  • Phagocytosis and Immune Regulation
  • Drug-Induced Adverse Reactions

McCluskey frequently collaborates with several co-authors who have contributed to multiple publications together. These include:

  • David P. Fairlie
  • Jamie Rossjohn
  • Alexandra J. Corbett
  • Jeffrey Y. W. Mak
  • Zhenjun Chen

Their work has been published in a variety of scientific venues, with recurring appearances in these journals:

  • Journal of Biological Chemistry
  • Nature Communications
  • The Journal of Immunology
  • Immunology and Cell Biology
  • Frontiers in Immunology

Representative recent papers by McCluskey include:

  • "Bempedoic Acid and Cardiovascular Outcomes in Statin-Intolerant Patients" (2023, New England Journal of Medicine)
  • "Genome-wide CRISPR-Cas9 screening reveals ubiquitous T cell cancer targeting via the monomorphic MHC class I-related protein MR1" (2020, Nature Immunology)
  • "Mucosal-associated invariant T cells promote inflammation and intestinal dysbiosis leading to metabolic dysfunction during obesity" (2020, Nature Communications)
  • "Exposure to SARS-CoV-2 generates T-cell memory in the absence of a detectable viral infection" (2021, Nature Communications)
  • "IL-17 production by tissue-resident MAIT cells is locally induced in children with pneumonia" (2020, Mucosal Immunology)

Best Publications

  • MR1 presents microbial vitamin B metabolites to MAIT cells

    Lars Kjer-Nielsen;Onisha G Patel;Alexandra J Corbett;Jerome Le Nours;Jerome Le Nours

  • More than one reason to rethink the use of peptides in vaccine design

    Anthony W. Purcell;James McCluskey;Jamie Rossjohn

  • Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

    Andrea Cossarizza;Hyun Dong Chang;Andreas Radbruch;Andreas Acs

  • T-cell activation by transitory neo-antigens derived from distinct microbial pathways

    Alexandra Corbett;Sidonia B G Eckle;Richard William Birkinshaw;Ligong Liu

  • The burgeoning family of unconventional T cells.

    Dale I Godfrey;Dale I Godfrey;Adam P Uldrich;Adam P Uldrich;James McCluskey;Jamie Rossjohn;Jamie Rossjohn;Jamie Rossjohn

  • T cell antigen receptor recognition of antigen-presenting molecules.

    Jamie Rossjohn;Stephanie Gras;John James Miles;Stephen J. Turner

  • Immune self-reactivity triggered by drug-modified HLA-peptide repertoire

    Patricia T Illing;Julian P Vivian;Nadine Lee Dudek;Lyudmila Kostenko

  • CD1d–lipid-antigen recognition by the semi-invariant NKT T-cell receptor

    Natalie Borg;Kwok Soon Wun;Lars Kjer-Nielsen;Matthew Charles James Wilce

  • Antigen-loaded MR1 tetramers define T cell receptor heterogeneity in mucosal-associated invariant T cells

    Rangsima Reantragoon;Alexandra Corbett;Isaac G Sakala;Nicholas A Gherardin;Nicholas A Gherardin

  • The biology and functional importance of MAIT cells.

    Dale I. Godfrey;Hui-Fern Koay;Hui-Fern Koay;James McCluskey;Nicholas A. Gherardin;Nicholas A. Gherardin

  • Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition)

    Unknown

  • Predisposition to abacavir hypersensitivity conferred by HLA-B*5701 and a haplotypic Hsp70-Hom variant

    Annalise M. Martin;David Nolan;Silvana Gaudieri;Silvana Gaudieri;Coral Ann Almeida

  • Comprehensive, Quantitative Mapping of T Cell Epitopes in Gluten in Celiac Disease

    Jason A. Tye-Din;Jessica A. Stewart;James A. Dromey;Tim Beissbarth

  • A molecular basis for the association of the HLA-DRB1 locus, citrullination, and rheumatoid arthritis

    Stephen Scally;Jan Petersen;Soi Cheng Cheng Law;Nadine Lee Dudek

  • Structural determinants of T-cell receptor bias in immunity

    Stephen J Turner;Peter C Doherty;James McCluskey;Jamie Rossjohn

  • Optimization of the MHC Class I Peptide Cargo Is Dependent on Tapasin

    Anthony P Williams;Chen Au Peh;Anthony W Purcell;James McCluskey

  • Impairment of immunity to Candida and Mycobacterium in humans with bi-allelic RORC mutations

    Satoshi Okada;Satoshi Okada;Janet G Markle;Elissa K Deenick;Elissa K Deenick;Federico Mele

  • A Structural Basis for the Selection of Dominant αβ T Cell Receptors in Antiviral Immunity

    Lars Kjer-Nielsen;Craig S. Clements;Anthony W. Purcell;Andrew G. Brooks

  • Human Leukocyte Antigen Class I-Restricted Activation of CD8+ T Cells Provides the Immunogenetic Basis of a Systemic Drug Hypersensitivity

    Diana Chessman;Lyudmila Kostenko;Tessa Lethborg;Anthony Wayne Purcell

  • Identification of phenotypically and functionally heterogeneous mouse mucosal-associated invariant t cells using MR1 tetramers

    Azad Rahimpour;Hui Fern Koay;Anselm Enders;Rhiannon Clanchy

  • A three-stage intrathymic development pathway for the mucosal-associated invariant T cell lineage

    Hui-Fern Koay;Nicholas A Gherardin;Nicholas A Gherardin;Anselm Enders;Liyen Loh

Frequent Co-Authors

Jamie Rossjohn
Jamie Rossjohn Monash University
Lars Kjer-Nielsen
Lars Kjer-Nielsen University of Melbourne
Anthony W. Purcell
Anthony W. Purcell Monash University
Zhenjun Chen
Zhenjun Chen University of Melbourne
Dale I. Godfrey
Dale I. Godfrey University of Melbourne
Scott R. Burrows
Scott R. Burrows QIMR Berghofer Medical Research Institute
David P. Fairlie
David P. Fairlie University of Queensland
John J. Miles
John J. Miles James Cook University
Travis Clarke Beddoe
Travis Clarke Beddoe La Trobe University
Andrew G. Brooks
Andrew G. Brooks University of Melbourne

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