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D-Index
44
Citations
6412
World Ranking
7229
National Ranking
325

Overview

Jean-Marie Zajac is affiliated with the Federal University of Toulouse Midi-Pyrénées in France. Their research primarily spans the field of neuroscience, with specific focus on cellular and molecular neuroscience, molecular biology, endocrine and autonomic systems, reproductive medicine, and social psychology.

Their scholarly work covers several research topics including:

  • Neuropeptides and animal physiology
  • Receptor mechanisms and signaling
  • Regulation of appetite and obesity
  • Hypothalamic control of reproductive hormones
  • Neuroendocrine regulation and behavior

Jean-Marie Zajac has published in venues such as:

  • Peptides
  • IUPHAR/BPS Guide to Pharmacology CITE

Recent papers authored or co-authored by Jean-Marie Zajac include:

  • Pharmacological insight into the activation of the human neuropeptide FF2 receptor (2020, Peptides)
  • Neuropeptide FF/neuropeptide AF receptors in GtoPdb v.2023.1 (2023, IUPHAR/BPS Guide to Pharmacology CITE)

Collaborators working frequently with Jean-Marie Zajac are:

  • Lionel Moulédous
  • Franck Talmont
  • Rémi Veneziano
  • Gilles Dietrich
  • Catherine Mollereau

Best Publications

  • Neuropeptide FF, pain and analgesia

    Michel Roumy;Jean-Marie Zajac

  • Autoradiographic distribution of mu and delta opiate receptors in rat brain using highly selective ligands

    R. Quirion;J.M. Zajac;J.L. Morgat;B.P. Roques

  • Deltakephalin, Tyr-D-Thr-Gly-Phe-Leu-Thr: A new highly potent and fully specific agonist for opiate δ-receptors

    Jean-Marie Zajac;Gilles Gacel;Françis Petit;Pierre Dodey

  • Further evidence that morphine-6 beta-glucuronide is a more potent opioid agonist than morphine.

    B Frances;R Gout;B Monsarrat;J Cros

  • Antinociceptive effects of intrathecally administered F8Famide and FMRFamide in the rat.

    Christine Gouardères;Maaja Sutak;Jean-Marie Zajac;Khem Jhamandas

  • Pharmacological characterization of human NPFF1 and NPFF2 receptors expressed in CHO cells by using NPY Y1 receptor antagonists

    Catherine Mollereau;Honoré Mazarguil;Delphine Marcus;Isabelle Quelven

  • Functional characterization of a human receptor for neuropeptide FF and related peptides

    Masato Kotani;Catherine Mollereau;Michel Detheux;Emmanuel Le Poul

  • Detailed distribution of neuropeptide FF receptors (NPFF1 and NPFF2) in the rat, mouse, octodon, rabbit, guinea pig, and marmoset monkey brains: a comparative autoradiographic study.

    Christine Gouardères;Alain Puget;Jean-Marie Zajac

  • The μ rather than the δ subtype of opioid receptors appears to be involved in enkephalin-induced analgesia

    Pierre Chaillet;Annie Coulaud;Jean-Marie Zajac;Marie-Claude Fournie-Zaluski

  • Role of opioid receptors in the spinal antinociceptive effects of neuropeptide FF analogues

    Christine Gouardères;Khem Jhamandas;Maaja Sutak;Jean-Marie Zajac

  • Opioid-modulating Peptides: Mechanisms of Action

    Catherine Mollereau;Michel Roumy;Jean-Marie Zajac

  • Analogues of F8Famide resistant to degradation, with high affinity and in vivo effects.

    Sophie Gicquel;Honoré Mazarguil;Michelle Allard;Guy Simonnet

  • Functional differences between NPFF1 and NPFF2 receptor coupling: High intrinsic activities of RFamide-related peptides on stimulation of [35S]GTPγS binding

    Christine Gouardères;H Mazarguil;Catherine Mollereau;Nicolas Chartrel

  • High resolution radioautographic localization of [125I]FK-33-824-labelled mu opioid receptors in the spinal cord of normal and deafferented rats

    C. Gouardères;A. Beaudet;J.-M. Zajac;J. Cros

  • Autoradiographic study of μ and δ opioid binding sites and neutral endopeptidase-24.11 in rat after dorsal root rhizotomy

    J.-M. Zajac;M.-C. Lombard;M. Peschanski;J.-M. Besson

  • Quantitative autoradiographic distribution of NPFF1 neuropeptide FF receptor in the rat brain and comparison with NPFF2 receptor by using [125I]YVP and [125I]EYF as selective radioligands

    C Gouardères;I Quelven;C Mollereau;H Mazarguil

  • Structure-activity relationships of neuropeptide FF: Role of C-terminal regions

    Honoré H. Mazarguil;Christine C. Gouardères;Jean-André J.-A.M. Tafani;Delphine Marcus

  • Involvement of neuropeptide FF receptors in neuroadaptive responses to acute and chronic opiate treatments.

    Elhabazi K;Trigo Jm;Mollereau C;Moulédous L

  • Biovector nanoparticles improve antinociceptive efficacy of nasal morphine.

    D Betbeder;S Spérandio;J P Latapie;J de Nadai

  • Differences in Binding Properties of μ and δ Opioid Receptor Subtypes from Rat Brain: Kinetic Analysis and Effects of Ions and Nucleotides

    Jean-Marie Zajac;Bernard P. Roques

  • Opioid‐modulating properties of the neuropeptide FF system

    Lionel Moulédous;Catherine Mollereau;Jean-Marie Zajac

  • Neuropeptide FF (NPFF) Analogs Functionally Antagonize Opioid Activities in NPFF2 Receptor-Transfected SH-SY5Y Neuroblastoma Cells

    Catherine Mollereau;Honoré Mazarguil;Jean-Marie Zajac;Michel Roumy

  • Agonist and antagonist activities on human NPFF(2) receptors of the NPY ligands GR231118 and BIBP3226.

    Catherine Mollereau;Christine Gouardères;Yvan Dumont;Masato Kotani

  • Structure-Activity Study of Neuropeptide FF: Contribution of N-Terminal Regions to Affinity and Activity

    Sophie Gicquel;Honore Mazarguil;Corinne Desprat;Michele Allard

  • Physical Association between Neuropeptide FF and μ-Opioid Receptors as a Possible Molecular Basis for Anti-opioid Activity

    Michel Roumy;Corinne Lorenzo;Serge Mazères;Stéphanie Bouchet

Frequent Co-Authors

Guy Simonnet
Guy Simonnet University of Bordeaux
François Cesselin
François Cesselin Grenoble Alpes University
Michèle Allard
Michèle Allard Centre national de la recherche scientifique, CNRS
Michel Hamon
Michel Hamon Sorbonne University
Jean-Marie Besson
Jean-Marie Besson Grenoble Alpes University

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