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Satyabrata Kar

Satyabrata Kar

D-Index & Metrics

Neuroscience

D-Index
56
Citations
9192
World Ranking
4590
National Ranking
265

Overview

Satyabrata Kar is affiliated with the University of Alberta in Canada. Their research primarily focuses on medicine, with a notable emphasis on physiology and pharmacology. Their work integrates molecular biology, biomaterials, and computational theory and mathematics to explore various biochemical and neurobiological processes.

The scientist's main research topics include Alzheimer's disease research and treatments, cholinesterase and neurodegenerative diseases, and supramolecular self-assembly in materials. They have also contributed to computational drug discovery methods, neuroscience and neuropharmacology research, dementia and cognitive impairment research, and neuroinflammation and neurodegeneration mechanisms.

Significant recent publications by Satyabrata Kar are as follows:

  • "Significance of native PLGA nanoparticles in the treatment of Alzheimer's disease pathology" (2022) Bioactive Materials
  • "Unconjugated PLGA nanoparticles attenuate temperature-dependent β-amyloid aggregation and protect neurons against toxicity: implications for Alzheimer's disease pathology" (2022) Journal of Nanobiotechnology
  • "Mimosine functionalized gold nanoparticles (Mimo-AuNPs) suppress β-amyloid aggregation and neuronal toxicity" (2021) Bioactive Materials
  • "Significance of cytosolic cathepsin D in Alzheimer's disease pathology: Protective cellular effects of PLGA nanoparticles against β-amyloid-toxicity" (2020) Neuropathology and Applied Neurobiology
  • "Overview of the Neuroprotective Effects of the MAO-Inhibiting Antidepressant Phenelzine" (2021) Cellular and Molecular Neurobiology

Frequent co-authors of Kar include:

  • Holger Wille
  • Qi Wu
  • Govindarajan Karthivashan
  • Bibin G. Anand
  • Pallabi Sil Paul

The scientist has published multiple works in various journals, with the most frequent publication venues being:

  • Journal of Nanobiotechnology (3 publications)
  • Bioactive Materials (2 publications)
  • Neuropathology and Applied Neurobiology (1 publication)
  • Cellular and Molecular Neurobiology (1 publication)
  • Disease Models & Mechanisms (1 publication)

Best Publications

  • Interactions between β-amyloid and central cholinergic neurons: Implications for Alzheimer's disease.

    Satyabrata Kar;Stephen P.M. Slowikowski;David Westaway;Howard T.J. Mount

  • Amyloid β peptide induces tau phosphorylation and loss of cholinergic neurons in rat primary septal cultures

    W.-H Zheng;S Bastianetto;F Mennicken;W Ma

  • Insulin-like growth factor I protects and rescues hippocampal neurons against β-amyloid- and human amylin-induced toxicity

    Sylvain Doré;Satyabrata Kar;Rémi Quirion

  • Glutamate system, amyloid ß peptides and tau protein: functional interrelationships and relevance to Alzheimer disease pathology.

    Timothy J. Revett;Glen B. Baker;Jack Jhamandas;Satyabrata Kar

  • Quantitative autoradiographic localization of [125I]insulin-like growth factor I, [125I]insulin-like growth factor II, and [125I]insulin receptor binding sites in developing and adult rat brain.

    S. Kar;J.-G. Chabot;R. Quirion;R. Quirion

  • β-Amyloid peptides as direct cholinergic neuromodulators: a missing link?

    Daniel S. Auld;Satyabrata Kar;Rémi Quirion

  • Rediscovering an old friend, IGF-I: potential use in the treatment of neurodegenerative diseases.

    Sylvain Doré;Satyabrata Kar;Remi Quirion

  • Insulin-like growth factor-1-induced phosphorylation of transcription factor FKHRL1 is mediated by phosphatidylinositol 3-kinase/Akt kinase and role of this pathway in insulin-like growth factor-1-induced survival of cultured hippocampal neurons.

    Wen-Hua Zheng;Satyabrata Kar;Rémi Quirion

  • Amyloid β‐Peptide Inhibits High‐Affinity Choline Uptake and Acetylcholine Release in Rat Hippocampal Slices

    S. Kar;A. M. Issa;D. Seto;D. S. Auld

  • Insulin-like growth factor-1-induced phosphorylation of the forkhead family transcription factor FKHRL1 is mediated by Akt kinase in PC12 cells.

    Wen-Hua Zheng;Satyabrata Kar;Rémi Quirion

  • The insulin-like growth factor-II/mannose-6-phosphate receptor: structure, distribution and function in the central nervous system.

    Cheryl Hawkes;S. Kar;S. Kar

  • Predominant expression of Alzheimer's disease-associated BIN1 in mature oligodendrocytes and localization to white matter tracts.

    Pierre De Rossi;Virginie Buggia-Prévot;Benjamin L. L. Clayton;Jared B. Vasquez

  • Beta-amyloid-related peptides inhibit potassium-evoked acetylcholine release from rat hippocampal slices

    Satyabrata Kar;D. Seto;P. Gaudreau;R. Quirion

  • Insulin-like growth factor-1 (IGF-1): a neuroprotective trophic factor acting via the Akt kinase pathway

    W.-H. Zheng;S. Kar;S. Doré;R. Quirion

  • Cyclin-dependent protein kinase 5 primes microtubule-associated protein tau site-specifically for glycogen synthase kinase 3β

    Tong Li;Cheryl Hawkes;Hamid Y. Qureshi;Satyabrata Kar

  • Memantine protects rat cortical cultured neurons against beta-amyloid-induced toxicity by attenuating tau phosphorylation.

    M. S. Song;G. Rauw;G. B. Baker;S. Kar

  • Internalization of β-Amyloid Peptide by Primary Neurons in the Absence of Apolipoprotein E *

    Lucila Saavedra;Amany Mohamed;Victoria Ma;Satyabrata Kar

  • Distribution and levels of [125I]IGF-I, [125I]IGF-II and [125I]insulin receptor binding sites in the hippocampus of aged memory-unimpaired and -impaired rats

    S Doré;S Kar;W Rowe;R Quirion

  • Role of Cholesterol in APP Metabolism and Its Significance in Alzheimer’s Disease Pathogenesis

    M. Maulik;D. Westaway;J. H. Jhamandas;S. Kar

  • Fucoidan inhibits cellular and neurotoxic effects of β‐amyloid (Aβ) in rat cholinergic basal forebrain neurons

    Jack H. Jhamandas;Myung Bok Wie;Kim Harris;David MacTavish

  • Insulin-Like Growth Factors-I and -II Differentially Regulate Endogenous Acetylcholine Release from the Rat Hippocampal Formation

    S. Kar;D. Seto;S. Doré;U.-K. Hanisch

Frequent Co-Authors

Sylvain Doré
Sylvain Doré University of Florida
David Westaway
David Westaway University of Alberta
Jack H. Jhamandas
Jack H. Jhamandas University of Alberta
Adalberto Merighi
Adalberto Merighi University of Turin
James L. Henry
James L. Henry McMaster University
Brian Popko
Brian Popko Northwestern University
Rémi Quirion
Rémi Quirion McGill University
Badri N. Vardarajan
Badri N. Vardarajan Columbia University
Clinton T. Baldwin
Clinton T. Baldwin Boston University
Lindsay A. Farrer
Lindsay A. Farrer Boston University

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