Ignacio Torres-Aleman

Overview

Best Publications

• Circulating Insulin-Like Growth Factor I Mediates Exercise-Induced Increases in the Number of New Neurons in the Adult Hippocampus

  José Luis Trejo;Eva Carro;Ignacio Torres-Alemán

  1345
  Citations

• Circulating insulin-like growth factor I mediates effects of exercise on the brain.

  Eva Carro;Angel Nuñez;Svetlana Busiguina;Ignacio Torres-Aleman

  994
  Citations

• The many faces of insulin-like peptide signalling in the brain

  Ana M. Fernandez;Ignacio Torres-Alemán

  827
  Citations

• Circulating insulin-like growth factor I mediates the protective effects of physical exercise against brain insults of different etiology and anatomy.

  Eva Carro;Jose Luis Trejo;Svetlana Busiguina;Ignacio Torres-Aleman

  823
  Citations

• Serum insulin-like growth factor I regulates brain amyloid-beta levels.

  Carro E;Trejo Jl;Gomez-Isla T;LeRoith D

  705
  Citations

• Astrocytic Insulin Signaling Couples Brain Glucose Uptake with Nutrient Availability

  Cristina García-Cáceres;Carmelo Quarta;Luis Varela;Yuanqing Gao

  535
  Citations

• Insulin-like growth factor I is required for vessel remodeling in the adult brain

  C. Lopez-Lopez;D. LeRoith;I. Torres-Aleman

  487
  Citations

• Neuronal Activity Drives Localized Blood-Brain-Barrier Transport of Serum Insulin-like Growth Factor-I into the CNS

  Takeshi Nishijima;Joaquin Piriz;Sylvie Duflot;Ana M. Fernandez

  381
  Citations

• The effects of exercise on spatial learning and anxiety-like behavior are mediated by an IGF-I-dependent mechanism related to hippocampal neurogenesis.

  J.L. Trejo;M.V. LLorens-Martín;I. Torres-Alemán

  371
  Citations

• The role of insulin and insulin-like growth factor I in the molecular and cellular mechanisms underlying the pathology of Alzheimer's disease.

  Eva Carro;Ignacio Torres-Aleman

  329
  Citations

• Choroid Plexus Megalin Is Involved in Neuroprotection by Serum Insulin-Like Growth Factor I

  Eva Carro;Carlos Spuch;Jose Luis Trejo;Desiré Antequera

  258
  Citations

• Central actions of liver-derived insulin-like growth factor I underlying its pro-cognitive effects.

  J L Trejo;J Piriz;M V Llorens-Martin;A M Fernandez

  249
  Citations

• Circulating insulin-like growth factor I and cognitive function: Neuromodulation throughout the lifespan

  Andre Aleman;Ignacio Torres-Aleman

  216
  Citations

• Localization of insulin-like growth factor I (IGF-I)-like immunoreactivity in the developing and adult rat brain.

  L.M. García-Segura;J. Pérez;S. Pons;M.T. Rejas

  212
  Citations

• Toward a comprehensive neurobiology of IGF-I.

  Ignacio Torres-Aleman

  209
  Citations

• Therapeutic actions of insulin-like growth factor I on APP/PS2 mice with severe brain amyloidosis

  E. Carro;J.L. Trejo;A. Gerber;H. Loetscher

  201
  Citations

• Insulin-like growth factor I restores motor coordination in a rat model of cerebellar ataxia.

  A. M. Fernandez;A. Gonzalez de la Vega;I. Torres-Aleman

  184
  Citations

• Blockade of the insulin-like growth factor I receptor in the choroid plexus originates Alzheimer's-like neuropathology in rodents: new cues into the human disease?

  Eva Carro;Jose Luis Trejo;Carlos Spuch;Delphine Bohl

  178
  Citations

• Mechanisms mediating brain plasticity: IGF1 and adult hippocampal neurogenesis.

  María LLorens-Martín;Ignacio Torres-Alemán;José Luis Trejo

  171
  Citations

• Exercise modulates insulin-like growth factor 1-dependent and -independent effects on adult hippocampal neurogenesis and behaviour

  María LLorens-Martín;Ignacio Torres-Alemán;José Luis Trejo

  171
  Citations

• Localization of the insulin-like growth factor I receptor in the cerebellum and hypothalamus of adult rats: an electron microscopic study.

  L M Garcia-Segura;J R Rodriguez;I Torres-Aleman

  169
  Citations