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José Luis Trejo

José Luis Trejo

D-Index & Metrics

Neuroscience

D-Index
39
Citations
8390
World Ranking
8248
National Ranking
135

Overview

José Luis Trejo is affiliated with the Cajal Institute in Spain and specializes in Neuroscience. Their research work covers several subfields including Molecular Biology, Physiology, Developmental Neuroscience, Cognitive Neuroscience, and Neurology.

The scientist's main topics of research include:

  • Neurogenesis and neuroplasticity mechanisms
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Epigenetics and DNA Methylation
  • Tryptophan and brain disorders
  • Adipose Tissue and Metabolism
  • Birth, Development, and Health
  • Mitochondrial Function and Pathology

José Luis Trejo has coauthored frequently with:

  • Patricia Tezanos (14 publications)
  • Elisa Cintado (13 publications)
  • Pablo Muela (10 publications)
  • Kerry R. McGreevy (4 publications)
  • Raúl F. Pérez (3 publications)

Key recent publications by José Luis Trejo include:

  • "A toolbox for the longitudinal assessment of healthspan in aging mice," 2020, Nature Protocols
  • "Stratification of radiosensitive brain metastases based on an actionable S100A9/RAGE resistance mechanism," 2022, Nature Medicine
  • "<i>Dlk1</i> dosage regulates hippocampal neurogenesis and cognition," 2021, Proceedings of the National Academy of Sciences
  • "The Role of Smad2 in Adult Neuroplasticity as Seen through Hippocampal-Dependent Spatial Learning/Memory and Neurogenesis," 2021, Journal of Neuroscience
  • "Gαi2+ vomeronasal neurons govern the initial outcome of an acute social competition," 2020, Scientific Reports

The scientist regularly publishes in venues such as bioRxiv (Cold Spring Harbor Laboratory), The Anatomical Record, IBRO Neuroscience Reports, Journal of Neuroscience, and Scientific Reports.

Best Publications

  • Circulating Insulin-Like Growth Factor I Mediates Exercise-Induced Increases in the Number of New Neurons in the Adult Hippocampus

    José Luis Trejo;Eva Carro;Ignacio Torres-Alemán

  • Circulating insulin-like growth factor I mediates the protective effects of physical exercise against brain insults of different etiology and anatomy.

    Eva Carro;Jose Luis Trejo;Svetlana Busiguina;Ignacio Torres-Aleman

  • Serum insulin-like growth factor I regulates brain amyloid-beta levels.

    Carro E;Trejo Jl;Gomez-Isla T;LeRoith D

  • The effects of exercise on spatial learning and anxiety-like behavior are mediated by an IGF-I-dependent mechanism related to hippocampal neurogenesis.

    J.L. Trejo;M.V. LLorens-Martín;I. Torres-Alemán

  • Choroid Plexus Megalin Is Involved in Neuroprotection by Serum Insulin-Like Growth Factor I

    Eva Carro;Carlos Spuch;Jose Luis Trejo;Desiré Antequera

  • Central actions of liver-derived insulin-like growth factor I underlying its pro-cognitive effects.

    J L Trejo;J Piriz;M V Llorens-Martin;A M Fernandez

  • In vivo P2X7 inhibition reduces amyloid plaques in Alzheimer's disease through GSK3β and secretases

    Juan Ignacio Diaz-Hernandez;Juan Ignacio Diaz-Hernandez;Juan Ignacio Diaz-Hernandez;Rosa Gomez-Villafuertes;Rosa Gomez-Villafuertes;Rosa Gomez-Villafuertes;Miriam León-Otegui;Miriam León-Otegui;Lourdes Hontecillas-Prieto

  • Vitronectin regulates Sonic hedgehog activity during cerebellum development through CREB phosphorylation.

    Sebastián Pons;José L. Trejo;Juan Ramón Martínez-Morales;Elisa Martí

  • Therapeutic actions of insulin-like growth factor I on APP/PS2 mice with severe brain amyloidosis

    E. Carro;J.L. Trejo;A. Gerber;H. Loetscher

  • Inhibition of adult hippocampal neurogenesis disrupts contextual learning but spares spatial working memory, long-term conditional rule retention and spatial reversal.

    V. Hernández-Rabaza;M. Llorens-Martín;Clara Velázquez-Sánchez;A. Ferragud

  • Reducing GABAA α5 receptor-mediated inhibition rescues functional and neuromorphological deficits in a mouse model of down syndrome.

    Carmen Martínez-Cué;Paula Martínez;Noemí Rueda;Rebeca Vidal;Rebeca Vidal

  • Blockade of the insulin-like growth factor I receptor in the choroid plexus originates Alzheimer's-like neuropathology in rodents: new cues into the human disease?

    Eva Carro;Jose Luis Trejo;Carlos Spuch;Delphine Bohl

  • Mechanisms mediating brain plasticity: IGF1 and adult hippocampal neurogenesis.

    María LLorens-Martín;Ignacio Torres-Alemán;José Luis Trejo

  • Exercise modulates insulin-like growth factor 1-dependent and -independent effects on adult hippocampal neurogenesis and behaviour

    María LLorens-Martín;Ignacio Torres-Alemán;José Luis Trejo

  • An antagonist of estrogen receptors blocks the induction of adult neurogenesis by insulin-like growth factor-I in the dentate gyrus of adult female rat.

    Margarita Perez‐Martin;Iñigo Azcoitia;Jose Luis Trejo;Amanda Sierra

  • Brain repair and neuroprotection by serum insulin-like growth factor I.

    Eva Carro;Jose Luis Trejo;Angel Núñez;Ignacio Torres-Aleman

  • Role of insulin-like growth factor I signaling in neurodegenerative diseases.

    José Luis Trejo;Eva Carro;Eva Garcia-Galloway;Ignacio Torres-Aleman

  • A toolbox for the longitudinal assessment of healthspan in aging mice.

    Ilaria Bellantuono;R. de Cabo;D. Ehninger;C. Di Germanio

  • The hippocampal dentate gyrus is essential for generating contextual memories of fear and drug-induced reward.

    V. Hernández-Rabaza;L. Hontecillas-Prieto;C. Velázquez-Sánchez;A. Ferragud

  • Pronounced individual variation in the response to the stimulatory action of exercise on immature hippocampal neurons.

    M Llorens-Martín;I Torres-Alemán;J L Trejo

  • Memantine normalizes several phenotypic features in the Ts65Dn mouse model of Down syndrome.

    Noemí Rueda;María Llorens-Martín;Jesús Flórez;Elsa Valdizán;Elsa Valdizán;Elsa Valdizán

Frequent Co-Authors

Ignacio Torres-Aleman
Ignacio Torres-Aleman Achucarro Basque Center for Neuroscience
María Llorens-Martín
María Llorens-Martín Spanish National Research Council
Luis M. Garcia-Segura
Luis M. Garcia-Segura Spanish National Research Council
Laura López-Mascaraque
Laura López-Mascaraque Spanish National Research Council
Angel Nuñez
Angel Nuñez Autonomous University of Madrid
Juan J. Canales
Juan J. Canales University of Tasmania
Eduardo D. Martín
Eduardo D. Martín Yale School of Medicine
Alino Martinez-Marcos
Alino Martinez-Marcos University of Castilla-La Mancha
Angel Pazos
Angel Pazos University of Cantabria
Anne C. Ferguson-Smith
Anne C. Ferguson-Smith University of Cambridge

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