2026 Miguel Díaz-Hernández: Biology and Biochemistry Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Biology and Biochemistry	48	18499	16974	423	414	93	6511

Overview

Miguel Díaz-Hernández is affiliated with the Complutense University of Madrid in Spain. Their research primarily focuses on biochemical and molecular biological processes, with significant contributions intersecting the fields of medicine and physiology. The scientist's work broadly addresses molecular mechanisms relevant to neurological disorders and brain diseases.

The main academic fields of study for Díaz-Hernández include:

Biochemistry, Genetics and Molecular Biology
Medicine

Within these fields, their subfields of specialization encompass:

Physiology
Genetics
Biological Psychiatry
Endocrinology, Diabetes and Metabolism
Molecular Biology

The research topics frequently explored by Díaz-Hernández are:

Adenosine and Purinergic Signaling
Tryptophan and brain disorders
Alkaline Phosphatase Research Studies
Alzheimer's disease research and treatments
Neurological Complications and Syndromes
Genetics and Neurodevelopmental Disorders
Connective tissue disorders research

Frequent co-authors collaborating with Díaz-Hernández include:

Álvaro Sebastián-Serrano
Carolina Bianchi
Lucía Soria-Tobar
Beatriz Alvarez-Castelao
Caterina Di Lauro

Key publication venues where Díaz-Hernández's research has appeared are:

Frontiers in Molecular Neuroscience
Alzheimer s Research & Therapy
Methods in Molecular Biology
Research Square
Progress in Neurobiology

Recent notable publications by Díaz-Hernández include:

"The Role of P2X7 Receptor in Alzheimer's Disease" (2020), published in Frontiers in Molecular Neuroscience
"P2X7 receptor blockade reduces tau induced toxicity, therapeutic implications in tauopathies" (2021), published in Progress in Neurobiology
"P2X7 receptor inhibition ameliorates ubiquitin-proteasome system dysfunction associated with Alzheimer's disease" (2023), published in Alzheimer s Research & Therapy
"TNAP and P2X7R: New Plasma Biomarkers for Alzheimer's Disease" (2023), published in International Journal of Molecular Sciences
"Editorial: P2X7 as Common Therapeutic Target in Brain Diseases" (2021), published in Frontiers in Molecular Neuroscience

Best Publications

Neuronal induction of the immunoproteasome in Huntington's disease

Miguel Díaz-Hernández;Félix Hernández;Ester Martín-Aparicio;Pilar Gómez-Ramos

324
Citations
Extracellular tau is toxic to neuronal cells.

Alberto Gómez-Ramos;Miguel Díaz-Hernández;Raquel Cuadros;Félix Hernández

282
Citations
Altered P2X7-receptor level and function in mouse models of Huntington’s disease and therapeutic efficacy of antagonist administration

Miguel Díaz-Hernández;Miguel Díaz-Hernández;María Díez-Zaera;Jesús Sánchez-Nogueiro;Jesús Sánchez-Nogueiro;Rosa Gómez-Villafuertes

282
Citations
Extracellular tau promotes intracellular calcium increase through M1 and M3 muscarinic receptors in neuronal cells

A. Gómez-Ramos;M. Díaz-Hernández;A. Rubio;M.T. Miras-Portugal

270
Citations
In vivo P2X7 inhibition reduces amyloid plaques in Alzheimer's disease through GSK3β and secretases

Juan Ignacio Diaz-Hernandez;Juan Ignacio Diaz-Hernandez;Juan Ignacio Diaz-Hernandez;Rosa Gomez-Villafuertes;Rosa Gomez-Villafuertes;Rosa Gomez-Villafuertes;Miriam León-Otegui;Miriam León-Otegui;Lourdes Hontecillas-Prieto

230
Citations
Loss of striatal type 1 cannabinoid receptors is a key pathogenic factor in Huntington’s disease

Cristina Blázquez;Anna Chiarlone;Onintza Sagredo;Tania Aguado

229
Citations
Seizure suppression and neuroprotection by targeting the purinergic P2X7 receptor during status epilepticus in mice

Tobias Engel;Rosa Gomez-Villafuertes;Rosa Gomez-Villafuertes;Katsuhiro Tanaka;Guillaume Mesuret

225
Citations
Increased neocortical expression of the P2X7 receptor after status epilepticus and anticonvulsant effect of P2X7 receptor antagonist A-438079

Alba Jimenez-Pacheco;Guillaume Mesuret;Amaya Sanz-Rodriguez;Katsuhiro Tanaka

187
Citations
Tissue-nonspecific Alkaline Phosphatase Promotes the Neurotoxicity Effect of Extracellular Tau

Miguel Díaz-Hernández;Alberto Gómez-Ramos;Alicia Rubio;Rosa Gómez-Villafuertes

179
Citations
Transient P2X7 Receptor Antagonism Produces Lasting Reductions in Spontaneous Seizures and Gliosis in Experimental Temporal Lobe Epilepsy

Alba Jimenez-Pacheco;Miguel Diaz-Hernandez;Marina Arribas-Blázquez;Amaya Sanz-Rodriguez

174
Citations
Inhibition of the ATP-gated P2X7 receptor promotes axonal growth and branching in cultured hippocampal neurons.

Miguel Díaz-Hernandez;Ana del Puerto;Juan Ignacio Díaz-Hernandez;María Diez-Zaera

165
Citations
Reduced expression of the TrkB receptor in Huntington's disease mouse models and in human brain

Silvia Ginés;Miquel Bosch;Sonia Marco;Núria Gavaldà

155
Citations
Neuronal P2X7 Receptor: Involvement in Neuronal Physiology and Pathology.

M. Teresa Miras-Portugal;Álvaro Sebastián-Serrano;Álvaro Sebastián-Serrano;Laura de Diego García;Laura de Diego García;Miguel Díaz-Hernández;Miguel Díaz-Hernández

151
Citations
Inhibition of 26S proteasome activity by huntingtin filaments but not inclusion bodies isolated from mouse and human brain.

Miguel Díaz‐Hernández;Adriana G. Valera;María A. Morán;Pilar Gómez‐Ramos

127
Citations
P2X7 Receptors in Rat Brain: Presence in Synaptic Terminals and Granule Cells

Maria Teresa Miras-Portugal;Miguel Díaz-Hernández;Lisandro Giráldez;Cristina Hervás

123
Citations
Accumulation of ubiquitin conjugates in a polyglutamine disease model occurs without global ubiquitin/proteasome system impairment

Christa J. Maynard;Claudia Böttcher;Zaira Ortega;Ruben Smith

120
Citations
Tissue-nonspecific alkaline phosphatase promotes axonal growth of hippocampal neurons

M. Díez-Zaera;J. I. Díaz-Hernández;E. Hernández-Álvarez;H. Zimmermann

119
Citations
Characteristics and consequences of muscarinic receptor activation by tau protein

Alberto Gómez-Ramos;Miguel Díaz-Hernández;Alicia Rubio;Juan Ignacio Díaz-Hernández

119
Citations
Diadenosine polyphosphate receptors. from rat and guinea-pig brain to human nervous system.

J Pintor;M Díaz-Hernández;J Gualix;R Gómez-Villafuertes

118
Citations
Acute polyglutamine expression in inducible mouse model unravels ubiquitin/proteasome system impairment and permanent recovery attributable to aggregate formation.

Zaira Ortega;Miguel Díaz-Hernández;Christa J. Maynard;Félix Hernández

117
Citations